2ZP7
 
 | | Crystal structure of LysN, alpha-aminoadipate aminotransferase (Leucine complex), from Thermus thermophilus HB27 | | 分子名称: | Alpha-aminodipate aminotransferase, LEUCINE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Tomita, T, Miyazaki, T, Miyagawa, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2008-06-30 | | 公開日 | 2009-01-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus
Proteins, 2008
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3CBF
 | | Crystal structure of LysN, alpha-aminoadipate aminotransferase, from Thermus thermophilus HB27 | | 分子名称: | (2S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]hexanedioic acid, Alpha-aminodipate aminotransferase | | 著者 | Tomita, T, Miyazaki, T, Miyagawa, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2008-02-21 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Mechanism for multiple-substrates recognition of alpha-aminoadipate aminotransferase from Thermus thermophilus
Proteins, 2008
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6IPV
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6IPW
 | | Crystal structure of CqsB2 from Streptomyces exfoliatus in complex with the product, 1-(2-hydroxypropyl)-2-methyl-carbazole-3,4-dione | | 分子名称: | 2-methyl-1-[(2R)-2-oxidanylpropyl]-9H-carbazole-3,4-dione, CqsB2 | | 著者 | Tomita, T, Kobayashi, M, Nishiyama, M, Kuzuyama, T. | | 登録日 | 2018-11-05 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | An Unprecedented Cyclization Mechanism in the Biosynthesis of Carbazole Alkaloids in Streptomyces.
Angew.Chem.Int.Ed.Engl., 58, 2019
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1X0L
 | | Crystal structure of tetrameric homoisocitrate dehydrogenase from an extreme thermophile, Thermus thermophilus | | 分子名称: | Homoisocitrate dehydrogenase | | 著者 | Miyazaki, J, Asada, K, Fushinobu, S, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2005-03-24 | | 公開日 | 2005-10-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal Structure of Tetrameric Homoisocitrate Dehydrogenase from an Extreme Thermophile, Thermus thermophilus: Involvement of Hydrophobic Dimer-Dimer Interaction in Extremely High Thermotolerance
J.Bacteriol., 187, 2005
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6ITD
 | | Crystal structure of BioU (K124A) from Synechocystis sp.PCC6803 in complex with the analog of reaction intermediate, 3-(1-aminoethyl)-nonanedioic acid | | 分子名称: | 3-(1-AMINOETHYL)NONANEDIOIC ACID, Slr0355 protein | | 著者 | Sakaki, K, Tomita, T, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2018-11-21 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria.
Nat.Chem.Biol., 16, 2020
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6IR4
 | | Crystal structure of BioU from Synechocystis sp.PCC6803 (apo form) | | 分子名称: | Slr0355 protein | | 著者 | Sakaki, K, Oishi, K, Shimizu, T, Tomita, T, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2018-11-10 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria.
Nat.Chem.Biol., 16, 2020
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6K36
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6K37
 | | Crystal structure of BioU (K124A) from Synechocystis sp.PCC6803 in complex with NAD+ and the analog of reaction intermediate, 3-(1-aminoethyl)-nonanedioic acid | | 分子名称: | (3R)-3-[(1R)-1-azanylethyl]nonanedioic acid, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Slr0355 protein | | 著者 | Sakaki, K, Tomita, T, Nishiyama, M. | | 登録日 | 2019-05-16 | | 公開日 | 2020-02-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A suicide enzyme catalyzes multiple reactions for biotin biosynthesis in cyanobacteria.
Nat.Chem.Biol., 16, 2020
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2ZYF
 | | Crystal structure of homocitrate synthase from Thermus thermophilus complexed with magnesuim ion and alpha-ketoglutarate | | 分子名称: | 2-OXOGLUTARIC ACID, Homocitrate synthase, MAGNESIUM ION | | 著者 | Okada, T, Tomita, T, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2009-01-20 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Mechanism of substrate recognition and insight into feedback inhibition of homocitrate synthase from thermus thermophilus
J.Biol.Chem., 2009
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2ZYJ
 | | Crystal structure of LysN, alpha-aminoadipate aminotransferase (complexed with N-(5'-phosphopyridoxyl)-L-glutamate), from Thermus thermophilus HB27 | | 分子名称: | Alpha-aminodipate aminotransferase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid | | 著者 | Ouchi, T, Tomita, T, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2009-01-26 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates in alpha-aminoadipate aminotransferase from Thermus thermophilus.
Biochem.Biophys.Res.Commun., 388, 2009
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3A9I
 | | Crystal structure of homocitrate synthase from Thermus thermophilus complexed with Lys | | 分子名称: | COBALT (II) ION, Homocitrate synthase, LYSINE | | 著者 | Okada, T, Tomita, T, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2009-10-28 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanism of substrate recognition and insight into feedback inhibition of homocitrate synthase from Thermus thermophilus
J.Biol.Chem., 285, 2010
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3AOE
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3AOG
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3AH3
 | | Crystal structure of LR5-1, 3-isopropylmalate dehydrogenase created by directed evolution | | 分子名称: | 1,2-ETHANEDIOL, Homoisocitrate dehydrogenase, SULFATE ION | | 著者 | Tomita, T, Suzuki, Y, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2010-04-13 | | 公開日 | 2011-02-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Enhancement of the latent 3-isopropylmalate dehydrogenase activity of promiscuous homoisocitrate dehydrogenase by directed evolution
Biochem.J., 431, 2010
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2ZTK
 | | Crystal structure of homocitrate synthase from Thermus thermophilus complexed with homocitrate | | 分子名称: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, COPPER (II) ION, Homocitrate synthase | | 著者 | Okada, T, Tomita, T, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2008-10-06 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Mechanism of substrate recognition and insight into feedback inhibition of homocitrate synthase from Thermus thermophilus
J.Biol.Chem., 285, 2010
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2ZTJ
 | | Crystal structure of homocitrate synthase from Thermus thermophilus complexed with alpha-ketoglutarate | | 分子名称: | 2-OXOGLUTARIC ACID, COPPER (II) ION, Homocitrate synthase | | 著者 | Okada, T, Tomita, T, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2008-10-06 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanism of substrate recognition and insight into feedback inhibition of homocitrate synthase from Thermus thermophilus
J.Biol.Chem., 285, 2010
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3VV5
 | | Crystal structure of TTC0807 complexed with (S)-2-aminoethyl-L-cysteine (AEC) | | 分子名称: | Amino acid ABC transporter, binding protein, L-THIALYSINE, ... | | 著者 | Tomita, T, Kanemaru, Y, Hasebe, F, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2012-07-16 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Two ATP-Binding Cassette Transporters Involved in (S)-2-Aminoethyl-Cysteine Uptake in Thermus thermophilus
J.Bacteriol., 195, 2013
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3VVD
 | | Crystal structure of TTC0807 complexed with Ornithine | | 分子名称: | Amino acid ABC transporter, binding protein, L-ornithine | | 著者 | Tomita, T, Kanemaru, Y, Hasebe, F, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2012-07-21 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Two ATP-Binding Cassette Transporters Involved in (S)-2-Aminoethyl-Cysteine Uptake in Thermus thermophilus
J.Bacteriol., 195, 2013
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3VVE
 | | Crystal structure of TTC0807 complexed with Lysine | | 分子名称: | Amino acid ABC transporter, binding protein, LYSINE, ... | | 著者 | Tomita, T, Kanemaru, Y, Hasebe, F, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2012-07-21 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Two ATP-Binding Cassette Transporters Involved in (S)-2-Aminoethyl-Cysteine Uptake in Thermus thermophilus
J.Bacteriol., 195, 2013
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3VVF
 | | Crystal structure of TTC0807 complexed with Arginine | | 分子名称: | ARGININE, Amino acid ABC transporter, binding protein, ... | | 著者 | Tomita, T, Kanemaru, Y, Hasebe, F, Kuzuyama, T, Nishiyama, M. | | 登録日 | 2012-07-21 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Two ATP-Binding Cassette Transporters Involved in (S)-2-Aminoethyl-Cysteine Uptake in Thermus thermophilus
J.Bacteriol., 195, 2013
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8PAZ
 | | OXIDIZED NATIVE PSEUDOAZURIN FROM A. FAECALIS | | 分子名称: | COPPER (II) ION, PSEUDOAZURIN | | 著者 | Adman, E.T, Libeu, C.A.P. | | 登録日 | 1997-02-24 | | 公開日 | 1997-08-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Site-directed mutants of pseudoazurin: explanation of increased redox potentials from X-ray structures and from calculation of redox potential differences.
Biochemistry, 36, 1997
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6PAZ
 | | OXIDIZED MUTANT P80I PSEUDOAZURIN FROM A. FAECALIS | | 分子名称: | COPPER (II) ION, PSEUDOAZURIN | | 著者 | Adman, E.T, Libeu, C.A.P. | | 登録日 | 1997-02-21 | | 公開日 | 1997-08-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Site-directed mutants of pseudoazurin: explanation of increased redox potentials from X-ray structures and from calculation of redox potential differences.
Biochemistry, 36, 1997
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7PAZ
 | | REDUCED MUTANT P80I PSEUDOAZURIN FROM A. FAECALIS | | 分子名称: | COPPER (II) ION, PSEUDOAZURIN | | 著者 | Adman, E.T, Libeu, C.A.P. | | 登録日 | 1997-02-21 | | 公開日 | 1997-08-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Site-directed mutants of pseudoazurin: explanation of increased redox potentials from X-ray structures and from calculation of redox potential differences.
Biochemistry, 36, 1997
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1NTD
 | | STRUCTURE OF ALCALIGENES FAECALIS NITRITE REDUCTASE MUTANT M150E THAT CONTAINS ZINC | | 分子名称: | COPPER (II) ION, NITRITE REDUCTASE | | 著者 | Murphy, M.E.P, Adman, E.T, Turley, S. | | 登録日 | 1995-07-03 | | 公開日 | 1996-11-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of Alcaligenes faecalis nitrite reductase and a copper site mutant, M150E, that contains zinc.
Biochemistry, 34, 1995
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