2ZTJ
Crystal structure of homocitrate synthase from Thermus thermophilus complexed with alpha-ketoglutarate
Summary for 2ZTJ
Entry DOI | 10.2210/pdb2ztj/pdb |
Related | 2ZJK |
Descriptor | Homocitrate synthase, 2-OXOGLUTARIC ACID, COPPER (II) ION, ... (4 entities in total) |
Functional Keywords | (beta/alpha)8 tim barrel, substrate complex, amino-acid biosynthesis, lysine biosynthesis, transferase |
Biological source | Thermus thermophilus |
Cellular location | Cytoplasm (Potential): O87198 |
Total number of polymer chains | 1 |
Total formula weight | 43283.70 |
Authors | Okada, T.,Tomita, T.,Kuzuyama, T.,Nishiyama, M. (deposition date: 2008-10-06, release date: 2009-10-13, Last modification date: 2024-03-13) |
Primary citation | Okada, T.,Tomita, T.,Wulandari, A.P.,Kuzuyama, T.,Nishiyama, M. Mechanism of substrate recognition and insight into feedback inhibition of homocitrate synthase from Thermus thermophilus J.Biol.Chem., 285:4195-4205, 2010 Cited by PubMed: 19996101DOI: 10.1074/jbc.M109.086330 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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