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3V98
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S663D Stable-5-LOX
分子名称: Arachidonate 5-lipoxygenase, FE (II) ION
著者Gilbert, N.C, Rui, Z, Neau, D.B, Waight, M, Bartlett, S.G, Boeglin, W.E, Brash, A.R, Newcomer, M.E.
登録日2011-12-23
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.
Faseb J., 26, 2012
3THS
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Crystal structure of rat native liver Glycine N-methyltransferase complexed with 5-methyltetrahydrofolate pentaglutamate
分子名称: 5-methyltetrahydrofolate pentaglutamate, BETA-MERCAPTOETHANOL, Glycine N-methyltransferase, ...
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C.
登録日2011-08-19
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate.
Biochim.Biophys.Acta, 1824, 2011
3THR
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Crystal structure of rat native liver Glycine N-methyltransferase complexed with 5-methyltetrahydrofolate monoglutamate
分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Glycine N-methyltransferase, TRIS(HYDROXYETHYL)AMINOMETHANE
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C.
登録日2011-08-19
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate.
Biochim.Biophys.Acta, 1824, 2011
3V99
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S663D Stable-5-LOX in complex with Arachidonic Acid
分子名称: ARACHIDONIC ACID, Arachidonate 5-lipoxygenase, FE (II) ION
著者Gilbert, N.C, Rui, Z, Neau, D.B, Waight, M, Bartlett, S.G, Boeglin, W.E, Brash, A.R, Newcomer, M.E.
登録日2011-12-23
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.252 Å)
主引用文献Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663.
Faseb J., 26, 2012
3VF1
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Structure of a calcium-dependent 11R-lipoxygenase suggests a mechanism for Ca-regulation
分子名称: 11R-lipoxygenase, FE (II) ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
著者Eek, P, Jarving, R, Jarving, I, Gilbert, N.C, Newcomer, M.E, Samel, N.
登録日2012-01-09
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.473 Å)
主引用文献Structure of a Calcium-dependent 11R-Lipoxygenase Suggests a Mechanism for Ca2+ Regulation.
J.Biol.Chem., 287, 2012
3D40
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Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with diphosphate
分子名称: DIPHOSPHATE, FomA protein
著者Pakhomova, S, Bartlett, S.G, Augustus, A, Kuzuyama, T, Newcomer, M.E.
登録日2008-05-13
公開日2008-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Crystal Structure of Fosfomycin Resistance Kinase FomA from Streptomyces wedmorensis.
J.Biol.Chem., 283, 2008
3D41
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Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with MgAMPPNP and fosfomycin
分子名称: FOSFOMYCIN, FomA protein, MAGNESIUM ION, ...
著者Pakhomova, S, Bartlett, S.G, Augustus, A, Kuzuyama, T, Newcomer, M.E.
登録日2008-05-13
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Fosfomycin Resistance Kinase FomA from Streptomyces wedmorensis.
J.Biol.Chem., 283, 2008
3E4Y
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Crystal structure of a 33kDa catalase-related protein from Mycobacterium avium subsp. paratuberculosis. I2(1)2(1)2(1) crystal form
分子名称: GLYCEROL, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Pakhomova, S, Newcomer, M.E.
登録日2008-08-12
公開日2009-08-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structure and peroxidase activity of a 33-kDa catalase-related protein from Mycobacterium avium ssp. paratuberculosis.
Protein Sci., 18, 2009
3E4W
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Crystal structure of a 33kDa catalase-related protein from Mycobacterium avium subsp. paratuberculosis. P2(1)2(1)2(1) crystal form.
分子名称: GLYCEROL, HEXANE-1,6-DIOL, PHOSPHATE ION, ...
著者Pakhomova, S, Newcomer, M.E.
登録日2008-08-12
公開日2009-08-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure and peroxidase activity of a 33-kDa catalase-related protein from Mycobacterium avium ssp. paratuberculosis.
Protein Sci., 18, 2009
3DY5
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Allene oxide synthase 8R-lipoxygenase from Plexaura homomalla
分子名称: Allene oxide synthase-lipoxygenase protein, FE (II) ION, PROTOPORPHYRIN IX CONTAINING FE
著者Gilbert, N.C, Niebuhr, M, Tsuruta, H, Newcomer, M.E.
登録日2008-07-25
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献A covalent linker allows for membrane targeting of an oxylipin biosynthetic complex.
Biochemistry, 47, 2008
2FBK
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BU of 2fbk by Molmil
The Crystal Structure of HucR from Deinococcus radiodurans
分子名称: CHLORIDE ION, transcriptional regulator, MarR family
著者Bordelon, T, Wilkinson, S.P, Grove, A, Newcomer, M.E.
登録日2005-12-09
公開日2006-07-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of the Transcriptional Regulator HucR from Deinococcus radiodurans Reveals a Repressor Preconfigured for DNA Binding.
J.Mol.Biol., 360, 2006
2FNQ
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Insights from the X-ray crystal structure of coral 8R-lipoxygenase: calcium activation via A C2-like domain and a structural basis of product chirality
分子名称: Allene oxide synthase-lipoxygenase protein, CALCIUM ION, FE (II) ION
著者Oldham, M.L, Brash, A.R, Newcomer, M.E.
登録日2006-01-11
公開日2006-02-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Insights from the X-ray crystal structure of coral 8R-lipoxygenase: calcium activation via a C2-like domain and a structural basis of product chirality.
J.Biol.Chem., 280, 2005
2IDK
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BU of 2idk by Molmil
Crystal Structure of Rat Glycine N-Methyltransferase Complexed With Folate
分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Glycine N-methyltransferase
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Egli, M, Newcomer, M.E, Wagner, C.
登録日2006-09-15
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase.
J.Biol.Chem., 282, 2007
2IDJ
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Crystal Structure of Rat Glycine N-Methyltransferase Apoprotein, Monoclinic Form
分子名称: CALCIUM ION, Glycine N-methyltransferase
著者Luka, Z, Pakhomova, S, Loukachevitch, L.V, Egli, M, Newcomer, M.E, Wagner, C.
登録日2006-09-15
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase.
J.Biol.Chem., 282, 2007
1LQO
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BU of 1lqo by Molmil
Crystal Strutcure of the Fosfomycin Resistance Protein A (FosA) Containing Bound Thallium Cations
分子名称: MANGANESE (II) ION, PHOSPHATE ION, PROBABLE Fosfomycin Resistance Protein, ...
著者Rife, C.L, Pharris, R.E, Newcomer, M.E, Armstrong, R.N.
登録日2002-05-11
公開日2002-09-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a genomically encoded fosfomycin resistance protein (FosA) at 1.19 A resolution by MAD phasing off the L-III edge of Tl(+)
J.Am.Chem.Soc., 124, 2002
1LQP
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CRYSTAL STRUCTURE OF THE FOSFOMYCIN RESISTANCE PROTEIN (FOSA) CONTAINING BOUND SUBSTRATE
分子名称: FOSFOMYCIN, MANGANESE (II) ION, POTASSIUM ION, ...
著者Rife, C.L, Pharris, R.E, Newcomer, M.E, Armstrong, R.N.
登録日2002-05-11
公開日2002-09-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Crystal structure of a genomically encoded fosfomycin resistance protein (FosA) at 1.19 A resolution by MAD phasing off the L-III edge of Tl(+)
J.Am.Chem.Soc., 124, 2002
1NKI
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CRYSTAL STRUCTURE OF THE FOSFOMYCIN RESISTANCE PROTEIN A (FOSA) CONTAINING BOUND PHOSPHONOFORMATE
分子名称: MANGANESE (II) ION, PHOSPHONOFORMIC ACID, POTASSIUM ION, ...
著者Rife, C.L, Pharris, R.E, Newcomer, M.E, Armstrong, R.N.
登録日2003-01-03
公開日2004-01-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein, FosA.
Biochemistry, 43, 2004
1NPB
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Crystal structure of the fosfomycin resistance protein from transposon Tn2921
分子名称: GLYCEROL, SULFATE ION, fosfomycin-resistance protein
著者Pakhomova, S, Rife, C.L, Armstrong, R.N, Newcomer, M.E.
登録日2003-01-17
公開日2004-03-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of fosfomycin resistance protein FosA from transposon Tn2921.
Protein Sci., 13, 2004
1NNR
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Crystal structure of a probable fosfomycin resistance protein (PA1129) from Pseudomonas aeruginosa with sulfate present in the active site
分子名称: MANGANESE (II) ION, SULFATE ION, probable fosfomycin resistance protein
著者Rife, C.L, Pharris, R.E, Newcomer, M.E, Armstrong, R.N.
登録日2003-01-14
公開日2004-01-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein, FosA.
Biochemistry, 43, 2004
1LQK
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High Resolution Structure of Fosfomycin Resistance Protein A (FosA)
分子名称: MANGANESE (II) ION, PHOSPHATE ION, POTASSIUM ION, ...
著者Rife, C.L, Pharris, R.E, Newcomer, M.E, Armstrong, R.N.
登録日2002-05-10
公開日2002-09-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Crystal structure of a genomically encoded fosfomycin resistance protein (FosA) at 1.19 A resolution by MAD phasing off the L-III edge of Tl(+)
J.Am.Chem.Soc., 124, 2002
1QAB
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BU of 1qab by Molmil
The structure of human retinol binding protein with its carrier protein transthyretin reveals interaction with the carboxy terminus of RBP
分子名称: PROTEIN (retinol binding protein), PROTEIN (transthyretin), RETINOL
著者Naylor, H.M, Newcomer, M.E.
登録日1999-02-03
公開日1999-02-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The structure of human retinol-binding protein (RBP) with its carrier protein transthyretin reveals an interaction with the carboxy terminus of RBP.
Biochemistry, 38, 1999
1R8Y
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Crystal Structure of Mouse Glycine N-Methyltransferase (Monoclinic Form)
分子名称: BETA-MERCAPTOETHANOL, glycine N-methyltransferase
著者Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E.
登録日2003-10-28
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004
1R94
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Crystal Structure of IscA (MERCURY DERIVATIVE)
分子名称: MERCURY (II) ION, Protein yfhF
著者Bilder, P.W, Ding, H, Newcomer, M.E.
登録日2003-10-28
公開日2003-12-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the ancient, Fe-S scaffold IscA reveals a novel protein fold.
Biochemistry, 43, 2004
1R8X
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Crystal Structure of Mouse Glycine N-Methyltransferase (Tetragonal Form)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, glycine N-methyltransferase
著者Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E.
登録日2003-10-28
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004
1R74
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Crystal Structure of Human Glycine N-Methyltransferase
分子名称: BETA-MERCAPTOETHANOL, CITRIC ACID, Glycine N-methyltransferase
著者Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E.
登録日2003-10-17
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004

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