6ZQU
 
 | | Cryo-EM structure of mature Dengue virus 2 at 3.1 angstrom resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein | | 著者 | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | | 登録日 | 2020-07-10 | | 公開日 | 2021-01-20 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.
Nat Commun, 12, 2021
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6ZQJ
 | | Cryo-EM structure of trimeric prME spike of Spondweni virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, prM | | 著者 | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | | 登録日 | 2020-07-09 | | 公開日 | 2021-01-20 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.
Nat Commun, 12, 2021
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6ZQV
 | | Cryo-EM structure of mature Spondweni virus | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein | | 著者 | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | | 登録日 | 2020-07-10 | | 公開日 | 2021-01-20 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.
Nat Commun, 12, 2021
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6ZQI
 | | Cryo-EM structure of Spondweni virus prME | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein | | 著者 | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | | 登録日 | 2020-07-09 | | 公開日 | 2021-01-20 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.
Nat Commun, 12, 2021
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8R1J
 | | Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B. | | 分子名称: | Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | | 登録日 | 2023-11-02 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation.
Nat Commun, 15, 2024
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8R1L
 | | Structure of avian H5N1 influenza A polymerase in complex with human ANP32B. | | 分子名称: | Acidic leucine-rich nuclear phosphoprotein 32 family member B, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Carrique, L, Staller, E, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | | 登録日 | 2023-11-02 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation.
Nat Commun, 15, 2024
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8BS7
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6XZR
 | | Influenza C virus polymerase in complex with chicken ANP32A - Subclass 1 | | 分子名称: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-05 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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6XZQ
 | | Influenza C virus polymerase in complex with human ANP32A - Subclass 1 | | 分子名称: | Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-05 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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6XZP
 | | Influenza C virus polymerase in complex with chicken ANP32A - Subclass 4 | | 分子名称: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-05 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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6Y0C
 | | Influenza C virus polymerase in complex with human ANP32A - Subclass 2 | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*UP*UP*UP*U)-3'), ... | | 著者 | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-07 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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6XZG
 | | Influenza C virus polymerase in complex with chicken ANP32A - Subclass 3 | | 分子名称: | Influenza viral RNA (vRNA) promoter 47mer, LRRcap domain-containing protein, Polymerase acidic protein, ... | | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-04 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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6ZQW
 | | Cryo-EM structure of immature Spondweni virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, prM | | 著者 | Renner, M, Dejnirattisai, W, Carrique, L, Serna Martin, I, Karia, D, Ilca, S.L, Ho, S.F, Kotecha, A, Keown, J.R, Mongkolsapaya, J, Screaton, G.R, Grimes, J.M. | | 登録日 | 2020-07-10 | | 公開日 | 2021-01-20 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins.
Nat Commun, 12, 2021
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6O5K
 | | Murine TRIM28 Bbox1 domain | | 分子名称: | Transcription intermediary factor 1-beta, ZINC ION | | 著者 | Sun, Y, Keown, J.R, Goldstone, D.C. | | 登録日 | 2019-03-03 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family.
J.Mol.Biol., 431, 2019
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6VVG
 | | Structure of the Cydia pomonella Granulovirus kinase, PK-1 | | 分子名称: | ADENOSINE MONOPHOSPHATE, Arginine kinase | | 著者 | Oliver, M.R, Horne, C.R, Keown, J.R, Murphy, J.M, Metcalf, P. | | 登録日 | 2020-02-17 | | 公開日 | 2021-02-03 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory alpha C helix.
Nat Commun, 12, 2021
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6ARH
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5UD6
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5UI3
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5K3Q
 | | Rhesus macaques Trim5alpha Bbox2 domain | | 分子名称: | NITRATE ION, Tripartite motif-containing protein 5,Tripartite motif-containing protein 5, ZINC ION | | 著者 | Keown, J.K, Goldstone, D.C. | | 登録日 | 2016-05-19 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the Trim5 alpha Bbox2 domain from rhesus macaques describes a plastic oligomerisation interface.
J.Struct.Biol., 195, 2016
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6HUN
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6I28
 | | Crystal Structure of Cydia Pomonella PTP-2 phosphatase | | 分子名称: | CALCIUM ION, GLYCEROL, ORF98 PTP-2 | | 著者 | Huang, G, Keown, J.P, Oliver, M.R, Metcalf, P. | | 登録日 | 2018-10-31 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of protein tyrosine phosphatase-2 from Cydia pomonella granulovirus.
Acta Crystallogr.,Sect.F, 75, 2019
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8OKH
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8SMQ
 | | Crystal Structure of the N-terminal Domain of the Cryptic Surface Protein (CD630_25440) from Clostridium difficile. | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Minasov, G, Shuvalova, L, Brunzelle, J.S, Kiryukhina, O, Wawrzak, Z, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2023-04-26 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Protein target highlights in CASP15: Analysis of models by structure providers.
Proteins, 91, 2023
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5UA0
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5UGJ
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