8WTJ
 
 | | XBB.1.5.70 spike protein in complex with ACE2 | | 分子名称: | Processed angiotensin-converting enzyme 2, Spike glycoprotein | | 著者 | Feng, L.L, Feng, L.L. | | 登録日 | 2023-10-18 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.64 Å) | | 主引用文献 | Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding.
Plos Pathog., 19, 2023
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5GGZ
 | | Crystal structure of novel inhibitor bound with Hsp90 | | 分子名称: | Heat shock protein HSP 90-alpha, [2,4-bis(oxidanyl)-5-propan-2-yl-phenyl]-(2-ethoxy-7,8-dihydro-5~{H}-pyrido[4,3-d]pyrimidin-6-yl)methanone | | 著者 | Chen, T.T, Li, J, Xu, Y.C. | | 登録日 | 2016-06-16 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.015 Å) | | 主引用文献 | Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90
J. Med. Chem., 59, 2016
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7YTO
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3MON
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8XUR
 | | BA.2.86 Spike Trimer in complex with heparan sulfate | | 分子名称: | 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yue, C, Liu, P. | | 登録日 | 2024-01-14 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity
Natl Sci Rev, 2024
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8XUU
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8XUT
 | | XBB.1.5 Spike Trimer in complex with heparan sulfate | | 分子名称: | 2-O-sulfo-beta-L-altropyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Yue, C, Liu, P, Mao, X. | | 登録日 | 2024-01-14 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity
Natl Sci Rev, 2024
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7Y0W
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7Y0V
 | | The co-crystal structure of BA.1-RBD with Fab-5549 | | 分子名称: | 5549-Fab, Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Xiao, J.Y, Zhang, Y. | | 登録日 | 2022-06-06 | | 公開日 | 2022-09-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents.
Cell Rep, 41, 2022
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7Y0C
 | | Crystal structure of BD55-1403 and SARS-CoV-2 Omicron RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD55-1403 Fab heavy chain, BD55-1403 Fab light chain, ... | | 著者 | Zhang, Z, Xiao, J. | | 登録日 | 2022-06-04 | | 公開日 | 2022-09-28 | | 最終更新日 | 2023-04-12 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents.
Cell Rep, 41, 2022
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6WCZ
 | | CryoEM structure of full-length ZIKV NS5-hSTAT2 complex | | 分子名称: | Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION | | 著者 | Boxiao, W, Stephanie, T, Kang, Z, Maria, T.S, Jian, F, Jiuwei, L, Linfeng, G, Wendan, R, Yanxiang, C, Ethan, C.V, HeaJin, H, Matthew, J.E, Sean, E.O, Adolfo, G.S, Hong, Z, Rong, H, Jikui, S. | | 登録日 | 2020-03-31 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis for STAT2 suppression by flavivirus NS5.
Nat.Struct.Mol.Biol., 27, 2020
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7YR2
 | | SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7YQU
 | | SARS-CoV-2 BA.2.75 S Trimer (3 RBD Down) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7YQZ
 | | SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state3) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, S309 light chain, ... | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7YR0
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7YQW
 | | SARS-CoV-2 BA.2.75 S Trimer (3 RBD Down) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7YQX
 | | SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, ... | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7YQY
 | | SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, ... | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7YQT
 | | SARS-CoV-2 BA.2.75 S Trimer (1 RBD Up) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7YR3
 | | SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7YQV
 | | pH 5.5 SARS-CoV-2 BA.2.75 S Trimer (1 RBD Up) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7YR1
 | | SARS-CoV-2 BA.2.75 S Trimer in complex with XG2v024 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Wang, L. | | 登録日 | 2022-08-08 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
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7WRJ
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7WRY
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8X4Z
 | | BA.2.86 Spike Trimer with ins483V mutation (3 RBD down) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yue, C, Liu, P. | | 登録日 | 2023-11-16 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity
Natl Sci Rev, 2024
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