6BYF
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![BU of 6byf by Molmil](/molmil-images/mine/6byf) | |
8TU3
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![BU of 8tu3 by Molmil](/molmil-images/mine/8tu3) | Bruton's tyrosine kinase in complex with covalent inhibitor compound 10 | 分子名称: | 1-[(4R)-4-{[(6P,8S)-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}azepan-1-yl]propan-1-one, Tyrosine-protein kinase BTK | 著者 | Metrick, C.M. | 登録日 | 2023-08-15 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis. J.Med.Chem., 67, 2024
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8TU4
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![BU of 8tu4 by Molmil](/molmil-images/mine/8tu4) | Bruton's tyrosine kinase in complex with covalent inhibitor compound 25 | 分子名称: | N-methyl-N-[(1S,3r)-3-methyl-3-{[(6M,8S)-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}cyclobutyl]propanamide, Tyrosine-protein kinase BTK | 著者 | Metrick, C.M. | 登録日 | 2023-08-15 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis. J.Med.Chem., 67, 2024
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8TU5
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![BU of 8tu5 by Molmil](/molmil-images/mine/8tu5) | Bruton's tyrosine kinase in complex with covalent inhibitor compound 27 | 分子名称: | 1-[(1S,5S,6S)-6-methyl-6-{[(6M,8R)-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}-2-azabicyclo[3.2.0]heptan-2-yl]propan-1-one, Tyrosine-protein kinase BTK | 著者 | Metrick, C.M. | 登録日 | 2023-08-15 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis. J.Med.Chem., 67, 2024
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7XO4
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![BU of 7xo4 by Molmil](/molmil-images/mine/7xo4) | SARS-CoV-2 Omicron BA.1 Variant Spike Trimer with two mouse ACE2 Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-04-30 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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7XOA
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![BU of 7xoa by Molmil](/molmil-images/mine/7xoa) | SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with one mouse ACE2 Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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7XO5
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![BU of 7xo5 by Molmil](/molmil-images/mine/7xo5) | SARS-CoV-2 Omicron BA.1 Variant Spike Trimer with one mouse ACE2 Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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7XO9
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![BU of 7xo9 by Molmil](/molmil-images/mine/7xo9) | SARS-CoV-2 Omicron BA.2 Variant RBD complexed with human ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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7XO7
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![BU of 7xo7 by Molmil](/molmil-images/mine/7xo7) | SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with two human ACE2 Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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7XO8
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![BU of 7xo8 by Molmil](/molmil-images/mine/7xo8) | SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with three human ACE2 Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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7XO6
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![BU of 7xo6 by Molmil](/molmil-images/mine/7xo6) | SARS-CoV-2 Omicron BA.1 Variant RBD with mouse ACE2 Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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7XOD
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![BU of 7xod by Molmil](/molmil-images/mine/7xod) | SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with three JMB2002 Fab Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of JMB2002 Fab, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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7XOC
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![BU of 7xoc by Molmil](/molmil-images/mine/7xoc) | SARS-CoV-2 Omicron BA.2 Variant RBD complexed with mouse ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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7XOB
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![BU of 7xob by Molmil](/molmil-images/mine/7xob) | SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with two mouse ACE2 Bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | 著者 | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | 登録日 | 2022-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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6LRX
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![BU of 6lrx by Molmil](/molmil-images/mine/6lrx) | Marsupenaeus japonicus ferritin mutant(T158H) | 分子名称: | FE (III) ION, Ferritin, NICKEL (II) ION | 著者 | Zhao, G, Tan, X. | 登録日 | 2020-01-16 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | Converting histidine-induced 3D protein arrays in crystals into their 3D analogues in solution by metal coordination cross-linking. Commun Chem, 2020
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6LS2
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6LRU
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![BU of 6lru by Molmil](/molmil-images/mine/6lru) | Marsupenaeus japonicus ferritin mutant (T158H) | 分子名称: | FE (III) ION, Ferritin, IMIDAZOLE, ... | 著者 | Zhao, G, Tan, X, Zhang, T. | 登録日 | 2020-01-16 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Converting histidine-induced 3D protein arrays in crystals into their 3D analogues in solution by metal coordination cross-linking. Commun Chem, 2020
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6LRV
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6LRW
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![BU of 6lrw by Molmil](/molmil-images/mine/6lrw) | |
7WD0
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![BU of 7wd0 by Molmil](/molmil-images/mine/7wd0) | |
7WDF
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![BU of 7wdf by Molmil](/molmil-images/mine/7wdf) | |
7WD9
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![BU of 7wd9 by Molmil](/molmil-images/mine/7wd9) | |
7WD7
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![BU of 7wd7 by Molmil](/molmil-images/mine/7wd7) | |
7WCR
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![BU of 7wcr by Molmil](/molmil-images/mine/7wcr) | |
7WCZ
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![BU of 7wcz by Molmil](/molmil-images/mine/7wcz) | |