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1D1U
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USE OF AN N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE TO FACILITATE CRYSTALLIZATION AND ANALYSIS OF A PSEUDO-16-MER DNA MOLECULE CONTAINING G-A MISPAIRS
分子名称: DNA (5'-D(*AP*CP*GP*GP*CP*AP*CP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*GP*TP*G)-3'), PROTEIN (REVERSE TRANSCRIPTASE)
著者Cote, M.L, Yohannan, S, Georgiadis, M.M.
登録日1999-09-21
公開日2000-04-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Use of an N-terminal fragment from moloney murine leukemia virus reverse transcriptase to facilitate crystallization and analysis of a pseudo-16-mer DNA molecule containing G-A mispairs.
Acta Crystallogr.,Sect.D, 56, 2000
1D0E
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CRYSTAL STRUCTURES OF THE N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE COMPLEXED WITH NUCLEIC ACID: FUNCTIONAL IMPLICATIONS FOR TEMPLATE-PRIMER BINDING TO THE FINGERS DOMAIN
分子名称: 5'-D(*TP*TP*TP*CP*AP*TP*GP*CP*AP*TP*G)-3', REVERSE TRANSCRIPTASE
著者Najmudin, S, Cote, M.L, Sun, D, Yohannan, S, Montano, S.P, Gu, J, Georgiadis, M.M.
登録日1999-09-09
公開日2000-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain
J.Mol.Biol., 296, 2000
1I6J
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BU of 1i6j by Molmil
CRYSTAL STRUCTURE OF A PSEUDO-16-MER DNA WITH STACKED GUANINES AND TWO G-A MISPAIRS COMPLEXED WITH THE N-TERMINAL FRAGMENT OF MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE
分子名称: 5'-D(*AP*CP*GP*GP*GP*AP*CP*GP*AP*C)-3', 5'-D(*GP*TP*CP*GP*TP*C)-3', REVERSE TRANSCRIPTASE
著者Cote, M.L, Georgiadis, M.M.
登録日2001-03-02
公開日2001-09-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a pseudo-16-mer DNA with stacked guanines and two G-A mispairs complexed with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase.
Acta Crystallogr.,Sect.D, 57, 2001
1M6U
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BU of 1m6u by Molmil
Crystal Structure of a Novel DNA-binding domain from Ndt80, a Transcriptional Activator Required for Meiosis in Yeast
分子名称: Ndt80 protein, SULFATE ION
著者Montano, S.P, Cote, M.L, Fingerman, I, Pierce, M, Vershon, A.K, Georgiadis, M.M.
登録日2002-07-17
公開日2002-11-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast
Proc.Natl.Acad.Sci.USA, 99, 2002
1M7U
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BU of 1m7u by Molmil
Crystal structure of a novel DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast
分子名称: Ndt80 protein
著者Montano, S.P, Cote, M.L, Fingerman, I, Pierce, M, Vershon, A.K, Georgiadis, M.M.
登録日2002-07-22
公開日2002-11-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the DNA-binding domain from Ndt80, a transcriptional activator required for meiosis in yeast
Proc.Natl.Acad.Sci.USA, 99, 2002
1NND
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BU of 1nnd by Molmil
Arginine 116 is Essential for Nucleic Acid Recognition by the Fingers Domain of Moloney Murine Leukemia Virus Reverse Transcriptase
分子名称: Reverse Transcriptase
著者Crowther, R.L, Remeta, D.P, Minetti, C.A, Das, D, Montano, S.P, Georgiadis, M.M.
登録日2003-01-13
公開日2004-01-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase
Proteins, 57, 2004
2FJX
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RT29 bound to D(CTTGAATGCATTCAAG) in complex with MMLV RT catalytic fragment
分子名称: 2-(4-(4-CARBAMIMIDOYLPHENOXY)PHENYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXIMIDAMIDE, 5'-D(*CP*TP*TP*GP*AP*AP*TP*G)-3', 5'-D(P*CP*AP*TP*TP*CP*AP*AP*G)-3', ...
著者Goodwin, K.D, Georgiadis, M.M.
登録日2006-01-03
公開日2006-06-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128, 2006
2FJW
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d(CTTGAATGCATTCAAG) in complex with MMLV RT catalytic fragment
分子名称: 5'-D(*CP*TP*TP*GP*AP*AP*TP*G)-3', 5'-D(P*CP*AP*TP*TP*CP*AP*AP*G)-3', Reverse transcriptase
著者Goodwin, K.D, Georgiadis, M.M.
登録日2006-01-03
公開日2006-06-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.
J.Am.Chem.Soc., 128, 2006
2FVR
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BU of 2fvr by Molmil
A Structural Study of the CA Dinucleotide Step in the Integrase Processing Site of Moloney Murine Leukemia Virus
分子名称: 5'-D(*TP*CP*TP*TP*TP*CP*AP*TP*AP*TP*GP*AP*AP*AP*GP*A)-3', reverse transcriptase
著者Montano, S.P, Cote, M.L, Roth, M.J, Georgiadis, M.M.
登録日2006-01-31
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
2FVQ
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A Structural Study of the CA Dinucleotide Step in the Integrase Processing Site of Moloney Murine Leukemia Virus
分子名称: 5'-D(*CP*TP*TP*TP*CP*AP*TP*TP*AP*AP*TP*GP*AP*AP*AP*G)-3', reverse transcriptase
著者Montano, S.P, Cote, M.L, Roth, M.J, Georgiadis, M.M.
登録日2006-01-31
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
2FVP
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A Structural Study of the CA Dinucleotide Step in the Integrase Processing Site of Moloney Murine Leukemia Virus
分子名称: 5'-D(*TP*TP*TP*CP*AP*TP*TP*GP*CP*AP*AP*TP*GP*AP*AP*A)-3', Reverse transcriptase
著者Montano, S.P, Cote, M.L, Roth, M.J, Georgiadis, M.M.
登録日2006-01-31
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
2FVS
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BU of 2fvs by Molmil
A Structural Study of the CA Dinucleotide Step in the Integrase Processing Site of Moloney Murine Leukemia Virus
分子名称: 5'-D(*CP*AP*CP*AP*AP*TP*GP*AP*TP*CP*AP*TP*TP*GP*TP*G)-3', reverse transcriptase
著者Montano, S.P, Cote, M.L, Roth, M.J, Georgiadis, M.M.
登録日2006-01-31
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.
Nucleic Acids Res., 34, 2006
4OTN
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BU of 4otn by Molmil
Crystal structure of the C-terminal regulatory domain of murine GCN2
分子名称: 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 2-alpha kinase 4, SULFATE ION
著者He, H, Georgiadis, M.M.
登録日2014-02-13
公開日2014-04-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and Mammals.
J.Biol.Chem., 289, 2014
4QHD
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BU of 4qhd by Molmil
Crystal structure of apo human APE1
分子名称: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase
著者He, H, Chen, Q, Georgiadis, M.M.
登録日2014-05-28
公開日2014-11-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.
Biochemistry, 53, 2014
4QH9
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Crystal structure of Mn2+ bound human APE1
分子名称: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MANGANESE (II) ION
著者Chen, Q, He, H, Georgiadis, M.M.
登録日2014-05-27
公開日2014-11-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.175 Å)
主引用文献High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.
Biochemistry, 53, 2014
4OTM
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BU of 4otm by Molmil
Crystal structure of the C-terminal domain from yeast GCN2
分子名称: Serine/threonine-protein kinase GCN2
著者He, H, Georgiadis, M.M.
登録日2014-02-13
公開日2014-04-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and Mammals.
J.Biol.Chem., 289, 2014
4QHE
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BU of 4qhe by Molmil
Crystal structure of Mg2+ bound human APE1
分子名称: 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION
著者He, H, Chen, Q, Georgiadis, M.M.
登録日2014-05-28
公開日2014-11-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.
Biochemistry, 53, 2014
6X1Y
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Mre11 dimer in complex with small molecule modulator PFMI
分子名称: (5Z)-5-[(3-methoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nuclease SbcCD subunit D
著者Arvai, A.S, Moiani, D, Tainer, J.A.
登録日2020-05-19
公開日2020-06-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response.
Prog.Biophys.Mol.Biol., 163, 2021
1G5P
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BU of 1g5p by Molmil
NITROGENASE IRON PROTEIN FROM AZOTOBACTER VINELANDII
分子名称: IRON/SULFUR CLUSTER, NITROGENASE IRON PROTEIN
著者Strop, P, Takahara, P.M, Chiu, H.J, Angove, H.C, Burgess, B.K, Rees, D.C.
登録日2000-11-01
公開日2001-01-31
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the all-ferrous [4Fe-4S]0 form of the nitrogenase iron protein from Azotobacter vinelandii.
Biochemistry, 40, 2001
4M94
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d(ATCCGTTATAACGGAT) complexed with Moloney Murine Leukemia virus reverse transcriptase catalytic fragment
分子名称: 1,2-ETHANEDIOL, 5' d(ATCCGttA) 3', 5' d(TAACGGAT) 3', ...
著者Singh, I.
登録日2013-08-14
公開日2014-03-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition.
Acta Crystallogr.,Sect.D, 70, 2014
4M95
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d(ATCCGTTATAACGGAT)complexed with Moloney Murine Leukemia virus reverse transcriptase catalytic fragment
分子名称: 1,2-ETHANEDIOL, 5' d(ATCCGTTA) 3', 5' d(TAACGGAT) 3', ...
著者Singh, I.
登録日2013-08-14
公開日2014-03-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition.
Acta Crystallogr.,Sect.D, 70, 2014
6X1Z
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Mre11 dimer in complex with small molecule modulator PFMJ
分子名称: (5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ...
著者Arvai, A.S, Moiani, D, Tainer, J.A.
登録日2020-05-19
公開日2020-06-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response.
Prog.Biophys.Mol.Biol., 163, 2021
2NIP
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NITROGENASE IRON PROTEIN FROM AZOTOBACTER VINELANDII
分子名称: IRON/SULFUR CLUSTER, NITROGENASE IRON PROTEIN
著者Komiya, H, Georgiadis, M.M, Chakrabarti, P, Woo, D, Kornuc, J.J, Rees, D.C.
登録日1998-05-11
公開日1998-11-11
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational variability in structures of the nitrogenase iron proteins from Azotobacter vinelandii and Clostridium pasteurianum.
J.Mol.Biol., 280, 1998
1DE0
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MODULATING THE MIDPOINT POTENTIAL OF THE [4FE-4S] CLUSTER OF THE NITROGENASE FE PROTEIN
分子名称: IRON/SULFUR CLUSTER, NITROGENASE IRON PROTEIN
著者Jang, S.B, Seefeldt, L.C, Peters, J.W.
登録日1999-11-12
公開日2000-02-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Modulating the midpoint potential of the [4Fe-4S] cluster of the nitrogenase Fe protein.
Biochemistry, 39, 2000
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