1HB0
 
 | | Snapshots of serine protease catalysis: (D) acyl-enzyme intermediate between porcine pancreatic elastase and human beta-casomorphin-7 jumped to pH 10 for 2 minutes | | 分子名称: | CALCIUM ION, ELASTASE 1, SULFATE ION | | 著者 | Wilmouth, R.C, Edman, K, Neutze, R, Wright, P.A, Clifton, I.J, Schneider, T.R, Schofield, C.J, Hajdu, J. | | 登録日 | 2001-04-10 | | 公開日 | 2001-08-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
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1HAY
 | | Snapshots of serine protease catalysis: (B) acyl-enzyme intermediate between porcine pancreatic elastase and human beta-casomorphin-7 jumped to pH 10 for 10 seconds | | 分子名称: | CALCIUM ION, ELASTASE 1, SULFATE ION | | 著者 | Wilmouth, R.C, Edman, K, Neutze, R, Wright, P.A, Clifton, I.J, Schneider, T.R, Schofield, C.J, Hajdu, J. | | 登録日 | 2001-04-10 | | 公開日 | 2001-08-02 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
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1HAX
 | | Snapshots of serine protease catalysis: (A) acyl-enzyme intermediate between porcine pancreatic elastase and human beta-casomorphin-7 at pH 5 | | 分子名称: | BETA-CASOMORPHIN-7, CALCIUM ION, ELASTASE 1, ... | | 著者 | Wilmouth, R.C, Edman, K, Neutze, R, Wright, P.A, Clifton, I.J, Schneider, T.R, Schofield, C.J, Hajdu, J. | | 登録日 | 2001-04-10 | | 公開日 | 2001-08-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
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1H68
 | | sensory rhodopsin II | | 分子名称: | CHLORIDE ION, RETINAL, SENSORY RHODOPSIN II | | 著者 | Royant, A, Nollert, P, Edman, K, Neutze, R, Landau, E.M, Pebay-Peyroula, E, Navarro, J. | | 登録日 | 2001-06-08 | | 公開日 | 2001-08-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | X-Ray Structure of Sensory Rhodopsin II at 2.1 A Resolution
Proc.Natl.Acad.Sci.USA, 98, 2001
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1HAZ
 | | Snapshots of serine protease catalysis: (C) acyl-enzyme intermediate between porcine pancreatic elastase and human beta-casomorphin-7 jumped to pH 9 for 1 minute | | 分子名称: | BETA-CASOMORPHIN-7, CALCIUM ION, ELASTASE 1, ... | | 著者 | Wilmouth, R.C, Edman, K, Neutze, R, Wright, P.A, Clifton, I.J, Schneider, T.R, Schofield, C.J, Hajdu, J. | | 登録日 | 2001-04-10 | | 公開日 | 2001-08-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Nat.Struct.Biol., 8, 2001
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5G55
 | | 3-Quinoline Carboxamides inhibitors of Pi3K | | 分子名称: | 6-cyano-4-[[(1R)-1-(4-methylphenyl)ethyl]amino]quinoline-3-carboxamide, PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM, SULFATE ION | | 著者 | Edman, K, Phillips, C. | | 登録日 | 2016-05-20 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Discovery of Novel 3-Quinoline Carboxamides as Potent, Selective and Orally Bioavailable Inhibitors of Ataxia Telangiectasia Mutated (Atm) Kinase.
J.Med.Chem., 59, 2016
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7PWZ
 | | Crystal structure of 14-3-3 sigma in complex with a C-terminal Estrogen Receptoralpha phosphopeptide, stabilised by Pyrrolidone1 derivative 228 | | 分子名称: | 14-3-3 protein sigma, 2-oxidanyl-5-[(2~{R})-4-oxidanyl-5-oxidanylidene-2-(1-oxidanylidene-3~{H}-2-benzofuran-5-yl)-3-(phenylcarbonyl)-2~{H}-pyrrol-1-yl]benzoic acid, C-terminus of Estrogen receptor alpha, ... | | 著者 | Andrei, S.A, Bosica, F, O'Mahony, G, Ottmann, C. | | 登録日 | 2021-10-07 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction.
J.Med.Chem., 65, 2022
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7PWT
 | | Crystal structure of 14-3-3 sigma in complex with a C-terminal Estrogen Receptor alpha phosphopeptide, stabilised by pyrrolidone derivative 228 | | 分子名称: | (2~{R})-1-(2-hydroxyphenyl)-2-(4-nitrophenyl)-4-oxidanyl-3-(phenylcarbonyl)-2~{H}-pyrrol-5-one, 14-3-3 protein sigma, C-terminus of Estrogen receptor alpha, ... | | 著者 | Andrei, S.A, Bosica, F, O'Mahony, G, Ottmann, C. | | 登録日 | 2021-10-07 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.312 Å) | | 主引用文献 | Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction.
J.Med.Chem., 65, 2022
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2BB4
 | | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Asp-Phe at pH 5.0 | | 分子名称: | CALCIUM ION, Chymotrypsin-like elastase family member 1, SULFATE ION, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-17 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2BDA
 | | Porcine pancreatic elastase complexed with N-acetyl-NPI and Ala-Ala at pH 5.0 | | 分子名称: | CALCIUM ION, Chymotrypsin-like elastase family member 1, NPI, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-20 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2BDC
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2BDB
 | | Porcine pancreatic elastase complexed with Asn-Pro-Ile and Ala-Ala at pH 5.0 | | 分子名称: | ALANINE, CALCIUM ION, Elastase-1, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-20 | | 公開日 | 2006-05-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2BD2
 | | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Arg-Phe at pH 5.0 | | 分子名称: | CALCIUM ION, Chymotrypsin-like elastase family member 1, SULFATE ION, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-20 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2BD7
 | | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Arg-Phe at pH 5.0 (50 min soak) | | 分子名称: | CALCIUM ION, Chymotrypsin-like elastase family member 1, SULFATE ION, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-20 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2BD3
 | | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Lys-Ala-NH2 at pH 5.0 | | 分子名称: | CALCIUM ION, Chymotrypsin-like elastase family member 1, SULFATE ION, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-20 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2BD4
 | | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Lys-Ser at pH 5.0 | | 分子名称: | CALCIUM ION, Chymotrypsin-like elastase family member 1, SULFATE ION, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-20 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2BD9
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2BD5
 | | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Lys-Ser at pH 5 and immersed in pH 9 buffer for 30 seconds | | 分子名称: | CALCIUM ION, Chymotrypsin-like elastase family member 1, SULFATE ION, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-20 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2BD8
 | | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Arg-Phe at pH 5.0 (50 min soak) and immersed in pH 9 buffer for 30 seconds | | 分子名称: | CALCIUM ION, Chymotrypsin-like elastase family member 1, SULFATE ION, ... | | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | | 登録日 | 2005-10-20 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural analyses on intermediates in serine protease catalysis
J.Biol.Chem., 281, 2006
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2C0N
 | | Crystal Structure of A197 from STIV | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, A197, NICKEL (II) ION, ... | | 著者 | Larson, E.T, Reiter, D, Young, M, Lawrence, C.M. | | 登録日 | 2005-09-06 | | 公開日 | 2005-09-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structure of A197 from Sulfolobus Turreted Icosahedral Virus: A Crenarchaeal Viral Glycosyltransferase Exhibiting the Gt-A Fold.
J.Virol., 80, 2006
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2CO5
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