1CC0
 
 | | CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, rho GDP dissociation inhibitor alpha, ... | | 著者 | Longenecker, K.L, Read, P, Derewenda, U, Dauter, Z, Garrard, S, Walker, L, Somlyo, A.V, Somlyo, A.P, Nakamoto, R.K, Derewenda, Z.S. | | 登録日 | 1999-03-03 | | 公開日 | 2000-01-07 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (5 Å) | | 主引用文献 | How RhoGDI binds Rho.
Acta Crystallogr.,Sect.D, 55, 1999
|
|
3UBD
 | | Structure of N-terminal domain of RSK2 kinase in complex with flavonoid glycoside SL0101 | | 分子名称: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 3,4-di-O-acetyl-6-deoxy-alpha-L-mannopyranoside, Ribosomal protein S6 kinase alpha-3 | | 著者 | Utepbergenov, D, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2011-10-24 | | 公開日 | 2012-09-05 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Insights into the Inhibition of the p90 Ribosomal S6 Kinase (RSK) by the Flavonol Glycoside SL0101 from the 1.5 A Crystal Structure of the N-Terminal Domain of RSK2 with Bound Inhibitor.
Biochemistry, 51, 2012
|
|
1ESC
 | | THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES | | 分子名称: | ESTERASE | | 著者 | Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S. | | 登録日 | 1994-10-07 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
|
|
1F7C
 | | CRYSTAL STRUCTURE OF THE BH DOMAIN FROM GRAF, THE GTPASE REGULATOR ASSOCIATED WITH FOCAL ADHESION KINASE | | 分子名称: | RHOGAP PROTEIN | | 著者 | Longenecker, K.L, Derewenda, U, Sheffield, P.J, Zheng, Y, Derewenda, Z.S. | | 登録日 | 2000-06-26 | | 公開日 | 2000-12-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the BH domain from graf and its implications for Rho GTPase recognition.
J.Biol.Chem., 275, 2000
|
|
1R6J
 | | Ultrahigh resolution Crystal Structure of syntenin PDZ2 | | 分子名称: | CHLORIDE ION, Syntenin 1 | | 著者 | Kang, B.S, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2003-10-15 | | 公開日 | 2004-05-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (0.73 Å) | | 主引用文献 | The PDZ2 domain of syntenin at ultra-high resolution: bridging the gap between small molecule and macromolecular crystal chemistry
J.Mol.Biol., 338, 2004
|
|
1S99
 | | The structure and function of B. subtilis YkoF gene product: ligand free protein | | 分子名称: | ACETATE ION, CALCIUM ION, ykoF | | 著者 | Devedjiev, Y, Surendranath, Y, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2004-02-04 | | 公開日 | 2004-10-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The Structure and Ligand Binding Properties of the B.subtilis YkoF Gene Product, a Member of a Novel Family of Thiamin/HMP-binding Proteins
J.Mol.Biol., 343, 2004
|
|
1THT
 | | STRUCTURE OF A MYRISTOYL-ACP-SPECIFIC THIOESTERASE FROM VIBRIO HARVEYI | | 分子名称: | THIOESTERASE | | 著者 | Lawson, D.M, Derewenda, U, Serre, L, Ferri, S, Szitter, R, Wei, Y, Meighen, E.A, Derewenda, Z.S. | | 登録日 | 1994-04-19 | | 公開日 | 1995-06-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of a myristoyl-ACP-specific thioesterase from Vibrio harveyi.
Biochemistry, 33, 1994
|
|
1QVY
 | | Crystal structure of RhoGDI K(199,200)R double mutant | | 分子名称: | Rho GDP-dissociation inhibitor 1, SULFATE ION | | 著者 | Czepas, J, Devedjiev, Y, Krowarsh, D, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2003-08-29 | | 公開日 | 2004-02-10 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The impact of Lys-->Arg surface mutations on the crystallization of the globular domain of RhoGDI.
Acta Crystallogr.,Sect.D, 60, 2004
|
|
1SBR
 | | The structure and function of B. subtilis YkoF gene product: the complex with thiamin | | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, CALCIUM ION, ykoF | | 著者 | Devedjiev, Y, Surendranath, Y, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2004-02-11 | | 公開日 | 2004-10-05 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Structure and Ligand Binding Properties of the B.subtilis YkoF Gene Product, a Member of a Novel Family of Thiamin/HMP-binding Proteins
J.Mol.Biol., 343, 2004
|
|
1TBU
 | |
1KLL
 | | Molecular basis of mitomycin C resictance in streptomyces: Crystal structures of the MRD protein with and without a drug derivative | | 分子名称: | 1,2-CIS-1-HYDROXY-2,7-DIAMINO-MITOSENE, mitomycin-binding protein | | 著者 | Martin, T.W, Dauter, Z, Devedjiev, Y, Sheffield, P, Jelen, F, He, M, Sherman, D, Otlewski, J, Derewenda, Z.S, Derewenda, U. | | 登録日 | 2001-12-12 | | 公開日 | 2002-07-19 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002
|
|
1KMZ
 | | MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE | | 分子名称: | mitomycin-binding protein | | 著者 | Martin, T.W, Dauter, Z, Devedjiev, Y, Sheffield, P, Jelen, F, He, M, Sherman, D, Otlewski, J, Derewenda, Z.S, Derewenda, U. | | 登録日 | 2001-12-17 | | 公開日 | 2002-07-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002
|
|
1V1T
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEYKV peptide | | 分子名称: | BENZOIC ACID, SYNTENIN 1, TNEYKV PEPTIDE | | 著者 | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2004-04-23 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
|
|
1UUJ
 | | N-terminal domain of Lissencephaly-1 protein (Lis-1) | | 分子名称: | ACETATE ION, BENZOIC ACID, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB ALPHA SUBUNIT, ... | | 著者 | Cooper, D.R, Kim, M.H, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2003-12-22 | | 公開日 | 2004-07-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The Structure of the N-Terminal Domain of the Product of the Lissencephaly Gene Lis1 and its Functional Implications
Structure, 12, 2004
|
|
1UXO
 | | The crystal structure of the ydeN gene product from B. subtilis | | 分子名称: | Putative hydrolase YdeN | | 著者 | Janda, I.K, Devedjiev, Y, Cooper, D.R, Chruszcz, M, Derewenda, U, Gabrys, A, Minor, W, Joachimiak, A, Derewenda, Z.S, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-02-27 | | 公開日 | 2004-05-27 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution.
Acta Crystallogr. D Biol. Crystallogr., 60, 2004
|
|
1W9O
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEYYV peptide | | 分子名称: | BENZOIC ACID, SYNTENIN 1, TNEYYV PEPTIDE | | 著者 | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2004-10-15 | | 公開日 | 2006-03-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
|
|
1W9E
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEFYF peptide | | 分子名称: | BENZOIC ACID, SYNTENIN 1, TNEFYF PEPTIDE | | 著者 | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2004-10-09 | | 公開日 | 2006-03-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
|
|
1WAB
 | | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | 分子名称: | ACETATE ION, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | 著者 | Ho, Y.S, Swenson, L, Derewenda, U, Serre, L, Wei, Y, Dauter, Z, Hattori, M, Aoki, J, Arai, H, Adachi, T, Inoue, K, Derewenda, Z.S. | | 登録日 | 1996-10-30 | | 公開日 | 1997-11-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer.
Nature, 385, 1997
|
|
1Y7M
 | | Crystal Structure of the B. subtilis YkuD protein at 2 A resolution | | 分子名称: | CADMIUM ION, SULFATE ION, hypothetical protein BSU14040 | | 著者 | Bielnicki, J.A, Devedjiev, Y, Derewenda, U, Dauter, Z, Joachimiak, A, Derewenda, Z.S, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-12-09 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | B. subtilis ykuD protein at 2.0 A resolution: insights into the structure and function of a novel, ubiquitous family of bacterial enzymes.
Proteins, 62, 2006
|
|
1ESD
 | | THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES | | 分子名称: | ESTERASE, METHYLPHOSPHONIC ACID ESTER GROUP | | 著者 | Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S. | | 登録日 | 1994-10-07 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
|
|
1ESE
 | | THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES | | 分子名称: | DIETHYL PHOSPHONATE, ESTERASE | | 著者 | Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S. | | 登録日 | 1994-10-07 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A novel variant of the catalytic triad in the Streptomyces scabies esterase.
Nat.Struct.Biol., 2, 1995
|
|
1FTN
 | | CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA (H12) | | 著者 | Wei, Y, Zhang, Y, Derewenda, U, Liu, X, Minor, W, Nakamoto, R.K, Somlyo, A.V, Somlyo, A.P, Derewenda, Z.S. | | 登録日 | 1997-03-13 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of RhoA-GDP and its functional implications.
Nat.Struct.Biol., 4, 1997
|
|
2V66
 | |
3TGL
 | | STRUCTURE AND MOLECULAR MODEL REFINEMENT OF RHIZOMUCOR MIEHEI TRIACYLGLYCERIDE LIPASE: A CASE STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT | | 分子名称: | TRIACYL-GLYCEROL ACYLHYDROLASE | | 著者 | Brady, L, Brzozowski, A.M, Derewenda, Z.S, Dodson, E.J, Dodson, G.G, Tolley, S.P, Turkenburg, J.P, Christiansen, L, Huge-Jensen, B, Norskov, L, Thim, L. | | 登録日 | 1991-07-29 | | 公開日 | 1993-07-15 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | STRUCTURE AND MOLECULAR-MODEL REFINEMENT OF RHIZOMUCOR-MIEHEI TRIACYLGLYCERIDE LIPASE - A CASE-STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT.
Acta Crystallogr.,Sect.B, 48, 1992
|
|
3JSD
 | | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G. | | 登録日 | 2009-09-10 | | 公開日 | 2010-09-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published
|
|
