8A92
 
 | | p53-Y220C Core Domain in Complex with a Bromo-trifluoro-pyrazole-amine | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-bromanyl-5-(trifluoromethyl)-1H-pyrazol-3-amine, Cellular tumor antigen p53, ... | | 著者 | Stahlecker, J, Braun, M.B, Stehle, T, Boeckler, F.M. | | 登録日 | 2022-06-27 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C.
Rsc Med Chem, 13, 2022
|
|
7ZH8
 | | DYRK1a in Complex with a Bromo-Triazolo-Pyridine | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-bromanyl-3H-[1,2,3]triazolo[4,5-b]pyridine, CHLORIDE ION, ... | | 著者 | Dammann, M, Stahlecker, J, Stehle, T, Boeckler, F.M. | | 登録日 | 2022-04-05 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes.
J.Med.Chem., 65, 2022
|
|
4V30
 | |
4V32
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Y101F mutant | | 分子名称: | CEREBLON ISOFORM 4, S-Thalidomide, ZINC ION | | 著者 | Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B. | | 登録日 | 2014-10-15 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon.
J.Struct.Biol., 188, 2014
|
|
4V2Z
 | |
4V31
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Deoxyuridine | | 分子名称: | 2'-DEOXYURIDINE, CEREBLON ISOFORM 4, CITRATE ANION, ... | | 著者 | Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B. | | 登録日 | 2014-10-15 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon.
J.Struct.Biol., 188, 2014
|
|
6H9M
 | | Coiled-coil domain-containing protein 90B residues 43-125 from Homo sapiens fused to a GCN4 adaptor | | 分子名称: | Coiled-coil domain-containing protein 90B, mitochondrial,General control protein GCN4 | | 著者 | Adlakha, J, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | | 登録日 | 2018-08-04 | | 公開日 | 2019-02-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Characterization of MCU-Binding Proteins MCUR1 and CCDC90B - Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles.
Structure, 27, 2019
|
|
6H9L
 | |
5A1Q
 | |
2VBS
 | | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with PO4 | | 分子名称: | CHLORIDE ION, PHOSPHATE ION, RIBOFLAVIN KINASE, ... | | 著者 | Hartmann, M.D, Djuranovic, S, Ammelburg, M, Martin, J, Lupas, A.N, Zeth, K. | | 登録日 | 2007-09-16 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels.
Structure, 15, 2007
|
|
2VBT
 | | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP and PO4 | | 分子名称: | CYTIDINE-5'-DIPHOSPHATE, PHOSPHATE ION, RIBOFLAVIN KINASE, ... | | 著者 | Hartmann, M.D, Ammelburg, M, Djuranovic, S, Martin, J, Lupas, A.N, Zeth, K. | | 登録日 | 2007-09-16 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels.
Structure, 15, 2007
|
|
2VBU
 | | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Hartmann, M.D, Ammelburg, M, Djuranovic, S, Martin, J, Lupas, A.N, Zeth, K. | | 登録日 | 2007-09-16 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels.
Structure, 15, 2007
|
|
2VBV
 | | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP and FMN | | 分子名称: | CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Hartmann, M.D, Ammelburg, M, Djuranovic, S, Martin, J, Lupas, A.N, Zeth, K. | | 登録日 | 2007-09-16 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels.
Structure, 15, 2007
|
|
3ZRV
 | | The high resolution structure of a dimeric Hamp-Dhp fusion displays asymmetry - A291F mutant | | 分子名称: | HAMP, OSMOLARITY SENSOR PROTEIN ENVZ | | 著者 | Zeth, K, Hulko, M, Ferris, H.U, Martin, J. | | 登録日 | 2011-06-20 | | 公開日 | 2011-07-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Mechanism of Regulation of Receptor Histidine Kinases.
Structure, 20, 2012
|
|
3ZRX
 | |
3ZRW
 | | The structure of the dimeric Hamp-Dhp fusion A291V mutant | | 分子名称: | AF1503 PROTEIN, OSMOLARITY SENSOR PROTEIN ENVZ | | 著者 | Zeth, K, Hulko, M, Ferris, H.U, Martin, J, Lupas, A.N. | | 登録日 | 2011-06-20 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Mechanism of Regulation of Receptor Histidine Kinases.
Structure, 20, 2012
|
|
5AMI
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Wash I structure | | 分子名称: | CEREBLON ISOFORM 4, S-Thalidomide, ZINC ION | | 著者 | Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B. | | 登録日 | 2015-03-10 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Dynamics of the Cereblon Ligand Binding Domain.
Plos One, 10, 2015
|
|
2Y21
 | |
2Y20
 | | The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291I mutant | | 分子名称: | UNCHARACTERIZED PROTEIN, ZINC ION | | 著者 | Zeth, K, Ferris, H.U, Hulko, M, Lupas, A.N. | | 登録日 | 2010-12-12 | | 公開日 | 2011-07-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The Mechanisms of Hamp-Mediated Signaling in Transmembrane Receptors.
Structure, 19, 2011
|
|
2Y0T
 | |
2Y0Q
 | |
2RMN
 | |
2VC8
 | |
5AMJ
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Wash II structure | | 分子名称: | CEREBLON ISOFORM 4, PHOSPHATE ION, S-Thalidomide, ... | | 著者 | Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B. | | 登録日 | 2015-03-10 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Dynamics of the Cereblon Ligand Binding Domain.
Plos One, 10, 2015
|
|
5AMK
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in multiple conformations, hexagonal crystal form | | 分子名称: | CEREBLON ISOFORM 4, DIMETHYL SULFOXIDE, S-Thalidomide, ... | | 著者 | Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B. | | 登録日 | 2015-03-10 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Dynamics of the Cereblon Ligand Binding Domain.
Plos One, 10, 2015
|
|
