6DMP
| De Novo Design of a Protein Heterodimer with Specificity Mediated by Hydrogen Bond Networks | 分子名称: | Designed orthogonal protein DHD13_XAAA_A, Designed orthogonal protein DHD13_XAAA_B | 著者 | Chen, Z, Flores-Solis, D, Sgourakis, N.G, Baker, D. | 登録日 | 2018-06-05 | 公開日 | 2018-12-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Programmable design of orthogonal protein heterodimers. Nature, 565, 2019
|
|
7KXS
| Computational design of constitutively active cGAS | 分子名称: | Cyclic GMP-AMP synthase, ZINC ION | 著者 | Dowling, Q, Volkman, H.E, Gray, E.E, Ovchinnikov, S, Cambier, S, Bera, A.K, Bick, M, Kang, A, Stetson, D.B, King, N.P. | 登録日 | 2020-12-04 | 公開日 | 2021-12-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Computational design of constitutively active cGAS. Nat.Struct.Mol.Biol., 30, 2023
|
|
6XSS
| CryoEM structure of designed helical fusion protein C4_nat_HFuse-7900 | 分子名称: | C4_nat_HFuse-7900 | 著者 | Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. | 登録日 | 2020-07-16 | 公開日 | 2020-12-23 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Design of multi-scale protein complexes by hierarchical building block fusion. Nat Commun, 12, 2021
|
|
6XI6
| Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks | 分子名称: | helical fusion design | 著者 | Bera, A.K, Hsia, Y, Kang, A.S, Shankaran, B, Baker, D. | 登録日 | 2020-06-19 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Design of multi-scale protein complexes by hierarchical building block fusion. Nat Commun, 12, 2021
|
|
6XH5
| |
6TMS
| Crystal structure of a de novo designed hexameric helical-bundle protein | 分子名称: | SULFATE ION, a novel designed pore protein, affinity purification tag | 著者 | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | 登録日 | 2019-12-05 | 公開日 | 2020-04-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Computational design of transmembrane pores. Nature, 585, 2020
|
|
6TJ1
| Crystal structure of a de novo designed hexameric helical-bundle protein | 分子名称: | De novo designed WSHC6, purification tag | 著者 | Xu, C, Pei, X.Y, Luisi, B.F, Baker, D. | 登録日 | 2019-11-23 | 公開日 | 2020-04-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Computational design of transmembrane pores. Nature, 585, 2020
|
|
6CZI
| Structure of a redesigned beta barrel, mFAP1, bound to DFHBI | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, mFAP1 | 著者 | Doyle, L.A, Stoddard, B.L. | 登録日 | 2018-04-09 | 公開日 | 2018-09-19 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | De novo design of a fluorescence-activating beta-barrel. Nature, 561, 2018
|
|
6CZG
| |
6CZJ
| |
6CZH
| Structure of a redesigned beta barrel, mFAP0, bound to DFHBI | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, mFAP0 | 著者 | Doyle, L.A, Stoddard, B.L. | 登録日 | 2018-04-09 | 公開日 | 2018-09-19 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | De novo design of a fluorescence-activating beta-barrel. Nature, 561, 2018
|
|
8FAR
| |
8GAA
| |
8G8I
| |
8GA9
| |
8GAQ
| |
7UZL
| |
7UBC
| |
7UBF
| |
7UBD
| |
7UCP
| computationally designed macrocycle | 分子名称: | computationally designed cyclic peptide D8.3.p2 | 著者 | Bhardwaj, G, Baker, D, Rettie, S, Glynn, C, Sawaya, M. | 登録日 | 2022-03-17 | 公開日 | 2022-09-14 | 最終更新日 | 2022-09-28 | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | 主引用文献 | Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022
|
|
7UBE
| |
7UBI
| |
7UBH
| |
7UBG
| |