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1OVD
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THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A IN COMPLEX WITH OROTATE
分子名称: DIHYDROOROTATE DEHYDROGENASE A, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
登録日2003-03-26
公開日2003-08-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function.
J.Biol.Chem., 278, 2003
1ALQ
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CIRCULARLY PERMUTED BETA-LACTAMASE FROM STAPHYLOCOCCUS AUREUS PC1
分子名称: CARBONATE ION, CP254 BETA-LACTAMASE, SULFATE ION
著者Pieper, U, Herzberg, O.
登録日1997-06-02
公開日1997-09-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Circularly permuted beta-lactamase from Staphylococcus aureus PC1.
Biochemistry, 36, 1997
1QME
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BU of 1qme by Molmil
PENICILLIN-BINDING PROTEIN 2X (PBP-2X)
分子名称: PENICILLIN-BINDING PROTEIN 2X, SULFATE ION
著者Gordon, E.J, Mouz, N, Duee, E, Dideberg, O.
登録日1999-09-28
公開日2000-05-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of the Penicillin-Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance.
J.Mol.Biol., 299, 2000
1DXK
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BU of 1dxk by Molmil
Metallo-beta-lactamase from Bacillus cereus 569/H/9 C168S mutant
分子名称: BICARBONATE ION, CLASS B BETA-LACTAMASE, ZINC ION
著者Chantalat, L, Duee, E, Dideberg, O.
登録日2000-01-10
公開日2000-08-25
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural effects of the active site mutation cysteine to serine in Bacillus cereus zinc-beta-lactamase.
Protein Sci., 9, 2000
2QDS
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BU of 2qds by Molmil
Crystal Structure of the Zinc Carbapenemase CPHA in Complex with the Inhibitor D-Captopril
分子名称: 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID, Beta-lactamase, GLYCEROL, ...
著者Garau, G, Dideberg, O.
登録日2007-06-21
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.
Org.Biomol.Chem., 6, 2008
1EGR
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SEQUENCE-SPECIFIC 1H N.M.R. ASSIGNMENTS AND DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF REDUCED ESCHERICHIA COLI GLUTAREDOXIN
分子名称: GLUTAREDOXIN
著者Sodano, P, Xia, T.-H, Bushweller, J.H, Bjornberg, O, Holmgren, A, Billeter, M, Wuthrich, K.
登録日1991-10-08
公開日1993-10-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Sequence-specific 1H n.m.r. assignments and determination of the three-dimensional structure of reduced Escherichia coli glutaredoxin.
J.Mol.Biol., 221, 1991
1JUB
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BU of 1jub by Molmil
The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A
分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ...
著者Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
登録日2001-08-24
公開日2003-09-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
1JQX
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The R57A mutant of Lactococcus lactis dihydroorotate dehydrogenase A
分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ...
著者Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
登録日2001-08-09
公開日2003-09-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
1JRC
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The N67A mutant of Lactococcus lactis dihydroorotate dehydrogenase A
分子名称: FLAVIN MONONUCLEOTIDE, OROTIC ACID, dihydroorotate dehydrogenase A
著者Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
登録日2001-08-13
公開日2003-09-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
1JUE
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1.8 A resolution structure of native lactococcus lactis dihydroorotate dehydrogenase A
分子名称: ACETIC ACID, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
登録日2001-08-24
公開日2003-09-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
1GHI
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STRUCTURE OF BETA-LACTAMASE GLU166ASP:ASN170GLN MUTANT
分子名称: BETA-LACTAMASE, CARBONATE ION
著者Chen, C.C.H, Herzberg, O.
登録日2000-12-18
公開日2001-04-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine.
Biochemistry, 40, 2001
1DJA
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BU of 1dja by Molmil
STRUCTURE OF BETA-LACTAMASE PRECURSOR, K73H MUTANT, AT 298K
分子名称: BETA-LACTAMASE
著者Chen, C.C.H, Herzberg, O.
登録日1996-08-13
公開日1997-03-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and kinetics of the beta-lactamase mutants S70A and K73H from Staphylococcus aureus PC1.
Biochemistry, 35, 1996
1SPH
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BU of 1sph by Molmil
REFINED STRUCTURES OF THE ACTIVE S83C AND IMPAIRED S46D HPRS: EVIDENCE THAT PHOSPHORYLATION DOES NOT REQUIRE A BACKBONE CONFORMATIONAL TRANSITION
分子名称: HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR
著者Liao, D.-I, Herzberg, O.
登録日1994-11-03
公開日1995-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Refined structures of the active Ser83-->Cys and impaired Ser46-->Asp histidine-containing phosphocarrier proteins.
Structure, 2, 1994
1GHP
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BU of 1ghp by Molmil
STRUCTURES OF THE ACYL-ENZYME COMPLEX OF THE STAPHYLOCOCCUS AUREUS BETA-LACTAMASE MUTANT GLU166ASP:ASN170GLN WITH DEGRADED BENZYLPENICILLIN
分子名称: BETA-LACTAMASE, OPEN FORM - PENICILLIN G, SULFATE ION
著者Chen, C.C.H, Herzberg, O.
登録日2000-12-21
公開日2001-04-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine.
Biochemistry, 40, 2001
1JQV
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BU of 1jqv by Molmil
The K213E mutant of Lactococcus lactis Dihydroorotate dehydrogenase A
分子名称: ACETIC ACID, Dihydroorotate dehydrogenase A, FLAVIN MONONUCLEOTIDE, ...
著者Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
登録日2001-08-09
公開日2003-09-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
1JRB
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The P56A mutant of Lactococcus lactis dihydroorotate dehydrogenase A
分子名称: FLAVIN MONONUCLEOTIDE, OROTIC ACID, dihydroorotate dehydrogenase A
著者Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
登録日2001-08-13
公開日2003-09-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function
J.Biol.Chem., 278, 2003
1EGO
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BU of 1ego by Molmil
NMR STRUCTURE OF OXIDIZED ESCHERICHIA COLI GLUTAREDOXIN: COMPARISON WITH REDUCED E. COLI GLUTAREDOXIN AND FUNCTIONALLY RELATED PROTEINS
分子名称: GLUTAREDOXIN
著者Xia, T.-H, Bushweller, J.H, Sodano, P, Billeter, M, Bjornberg, O, Holmgren, A, Wuthrich, K.
登録日1991-10-08
公開日1993-10-31
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献NMR structure of oxidized Escherichia coli glutaredoxin: comparison with reduced E. coli glutaredoxin and functionally related proteins.
Protein Sci., 1, 1992
1GHM
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Structures of the acyl-enzyme complex of the staphylococcus aureus beta-lactamase mutant GLU166ASP:ASN170GLN with degraded cephaloridine
分子名称: 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, BETA-LACTAMASE, CARBONATE ION, ...
著者Chen, C.C.H, Herzberg, O.
登録日2000-12-19
公開日2001-04-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine.
Biochemistry, 40, 2001
1F76
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ESCHERICHIA COLI DIHYDROOROTATE DEHYDROGENASE
分子名称: Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, FORMIC ACID, ...
著者Norager, S, Jensen, K.F, Bjornberg, O, Larsen, S.
登録日2000-06-26
公開日2002-10-16
最終更新日2014-03-12
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献E. coli Dihydroorotate Dehydrogenase Reveals Structural and Functional Distinction between different classes of dihydroorotate dehydrogenases
Structure, 10, 2002
2C5W
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BU of 2c5w by Molmil
PENICILLIN-BINDING PROTEIN 1A (PBP-1A) ACYL-ENZYME COMPLEX (CEFOTAXIME) FROM STREPTOCOCCUS PNEUMONIAE
分子名称: 1,2-ETHANEDIOL, CEFOTAXIME, C3' cleaved, ...
著者Contreras-Martel, C, Job, V, Di Guilmi, A.-M, Vernet, T, Dideberg, O, Dessen, A.
登録日2005-11-02
公開日2005-12-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structure of Penicillin-Binding Protein 1A (Pbp1A) Reveals a Mutational Hotspot Implicated in Beta-Lactam Resistance in Streptococcus Pneumoniae.
J.Mol.Biol., 355, 2006
2C6W
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PENICILLIN-BINDING PROTEIN 1A (PBP-1A) FROM STREPTOCOCCUS PNEUMONIAE
分子名称: CHLORIDE ION, PENICILLIN-BINDING PROTEIN 1A, ZINC ION
著者Contreras-Martel, C, Job, V, Di Guilmi, A.-M, Vernet, T, Dideberg, O, Dessen, A.
登録日2005-11-14
公開日2005-12-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal Structure of Penicillin-Binding Protein 1A (Pbp1A) Reveals a Mutational Hotspot Implicated in Beta-Lactam Resistance in Streptococcus Pneumoniae.
J.Mol.Biol., 355, 2006
2GFK
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Crystal structure of the zinc-beta-lactamase l1 from stenotrophomonas maltophilia (inhibitor 2)
分子名称: 2,5-DIPHENYLFURAN-3,4-DICARBOXYLIC ACID, DI(HYDROXYETHYL)ETHER, Metallo-beta-lactamase L1, ...
著者Nauton, L, Garau, G, Kahn, R, Dideberg, O.
登録日2006-03-22
公開日2007-03-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.
J.Mol.Biol., 375, 2008
2GFJ
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Crystal structure of the zinc-beta-lactamase L1 from stenotrophomonas maltophilia (inhibitor 1)
分子名称: 1,3-DIPHENYL-1H-PYRAZOLE-4,5-DICARBOXYLIC ACID, Metallo-beta-lactamase L1, SULFATE ION, ...
著者Nauton, L, Garau, G, Kahn, R, Dideberg, O.
登録日2006-03-22
公開日2007-03-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.
J.Mol.Biol., 375, 2008
2HB9
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Crystal Structure of the Zinc-Beta-Lactamase L1 from Stenotrophomonas Maltophilia (Inhibitor 3)
分子名称: 4-AMINO-5-(2-METHYLPHENYL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOLE-3-THIONE, Metallo-beta-lactamase L1, SULFATE ION, ...
著者Nauton, L, Garau, G, Kahn, R, Dideberg, O.
登録日2006-06-14
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.
J.Mol.Biol., 375, 2008
2H6A
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Crystal structure of the zinc-beta-lactamase L1 from Stenotrophomonas maltophilia (mono zinc form)
分子名称: Metallo-beta-lactamase L1, SULFATE ION, ZINC ION
著者Nauton, L, Garau, G, Kahn, R, Dideberg, O.
登録日2006-05-31
公開日2007-04-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.
J.Mol.Biol., 375, 2008

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