4MS0
| Crystal structure of PDE10A2 with fragment ZT0443 (6-chloropyrimidine-2,4-diamine) | 分子名称: | 6-chloropyrimidine-2,4-diamine, NICKEL (II) ION, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 著者 | Sridhar, V, Badger, J, Logan, C, Chie-Leon, B, Nienaber, V. | 登録日 | 2013-09-18 | 公開日 | 2014-05-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography. J Biomol Screen, 19, 2014
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4POK
| Crystal structures of thioredoxin with mesna at 2.5A resolution | 分子名称: | 1-THIOETHANESULFONIC ACID, Thioredoxin | 著者 | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | 登録日 | 2014-02-25 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity J Pharmacol Clin Toxicol, 2, 2014
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4POM
| Crystal structures of thioredoxin with mesna at 1.85A resolution | 分子名称: | 1-THIOETHANESULFONIC ACID, Thioredoxin | 著者 | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | 登録日 | 2014-02-26 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity J Pharmacol Clin Toxicol, 2, 2014
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1XBB
| Crystal structure of the syk tyrosine kinase domain with Gleevec | 分子名称: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Tyrosine-protein kinase SYK | 著者 | Nienaber, V.L, Atwell, S, Adams, J.M, Badger, J, Buchanan, M.D, Feil, I.K, Froning, K.J, Gao, X, Hendle, J, Keegan, K, Leon, B.C, Muller-Deickmann, H.J, Noland, B.W, Post, K, Rajashankar, K.R, Ramos, A, Russell, M, Burley, S.K, Buchanan, S.G. | 登録日 | 2004-08-30 | 公開日 | 2004-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | A Novel Mode of Gleevec Binding Is Revealed by the Structure of Spleen Tyrosine Kinase J.Biol.Chem., 279, 2004
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1XBA
| Crystal structure of apo syk tyrosine kinase domain | 分子名称: | Tyrosine-protein kinase SYK | 著者 | Atwell, S, Adams, J.M, Badger, J, Buchanan, M.D, Feil, I.K, Froning, K.J, Gao, X, Hendle, J, Keegan, K, Leon, B.C, Muller-Deickmann, H.J, Nienaber, V.L, Noland, B.W, Post, K, Rajashankar, K.R, Ramos, A, Russell, M, Burley, S.K, Buchanan, S.G. | 登録日 | 2004-08-30 | 公開日 | 2004-11-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A novel mode of Gleevec binding is revealed by the structure of spleen tyrosine kinase. J.Biol.Chem., 279, 2004
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1O6B
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1O63
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1O6C
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1O67
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1O60
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1O62
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1O65
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1O66
| |
1O61
| |
1O68
| |
1O6D
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1O69
| Crystal structure of a PLP-dependent enzyme | 分子名称: | (2-AMINO-4-FORMYL-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, BETA-MERCAPTOETHANOL, aminotransferase | 著者 | Structural GenomiX | 登録日 | 2003-10-23 | 公開日 | 2003-11-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
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1O64
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1VGY
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1VHJ
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1VGU
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1VH0
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1VHL
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1VI1
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1VGV
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