1P02
 
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6D14
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2H5D
 | | 0.9A resolution crystal structure of alpha-lytic protease complexed with a transition state analogue, MeOSuc-Ala-Ala-Pro-Val boronic acid | | 分子名称: | ALPHA-LYTIC PROTEASE, GLYCEROL, MEOSUC-ALA-ALA-PRO-ALA BORONIC ACID INHIBITOR, ... | | 著者 | Fuhrmann, C.N, Agard, D.A. | | 登録日 | 2006-05-25 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | | 主引用文献 | Subangstrom crystallography reveals that short ionic hydrogen bonds, and not a His-Asp low-barrier hydrogen bond, stabilize the transition state in serine protease catalysis
J.Am.Chem.Soc., 128, 2006
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1P10
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1P09
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1P01
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1LE4
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1LE2
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7LPR
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5FLZ
 | | Cryo-EM structure of gamma-TuSC oligomers in a closed conformation | | 分子名称: | SPINDLE POLE BODY COMPONENT 110, SPINDLE POLE BODY COMPONENT SPC97, SPINDLE POLE BODY COMPONENT SPC98, ... | | 著者 | Greenberg, C.H, Kollman, J, Zelter, A, Johnson, R, MacCoss, M.J, Davis, T.N, Agard, D.A, Sali, A. | | 登録日 | 2015-10-29 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | Structure of Gamma-Tubulin Small Complex Based on a Cryo-Em Map, Chemical Cross-Links, and a Remotely Related Structure.
J.Struct.Biol., 194, 2016
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5FM1
 | | Structure of gamma-tubulin small complex based on a cryo-EM map, chemical cross-links, and a remotely related structure | | 分子名称: | SPINDLE POLE BODY COMPONENT 110, SPINDLE POLE BODY COMPONENT SPC97, SPINDLE POLE BODY COMPONENT SPC98, ... | | 著者 | Greenberg, C.H, Kollman, J, Zelter, A, Johnson, R, MacCoss, M.J, Davis, T.N, Agard, D.A, Sali, A. | | 登録日 | 2015-10-30 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Structure of Gamma-Tubulin Small Complex Based on a Cryo-Em Map, Chemical Cross-Links, and a Remotely Related Structure.
J.Struct.Biol., 194, 2016
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4M1X
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1Z5V
 | | Crystal structure of human gamma-tubulin bound to GTPgammaS | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Tubulin gamma-1 chain | | 著者 | Aldaz, H.A, Rice, L.M, Stearns, T, Agard, D.A. | | 登録日 | 2005-03-20 | | 公開日 | 2005-05-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.
Nature, 435, 2005
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1Z5W
 | | Crystal Structure of gamma-tubulin bound to GTP | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Tubulin gamma-1 chain | | 著者 | Aldaz, H.A, Rice, L.M, Stearns, T, Agard, D.A. | | 登録日 | 2005-03-20 | | 公開日 | 2005-05-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.
Nature, 435, 2005
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3PRO
 | | ALPHA-LYTIC PROTEASE COMPLEXED WITH C-TERMINAL TRUNCATED PRO REGION | | 分子名称: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, ALPHA-LYTIC PROTEASE | | 著者 | Sauter, N.K, Mau, T, Rader, S.D, Agard, D.A. | | 登録日 | 1998-08-26 | | 公開日 | 1999-04-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of alpha-lytic protease complexed with its pro region.
Nat.Struct.Biol., 5, 1998
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1L2I
 | | Human Estrogen Receptor alpha Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol and a Glucocorticoid Receptor Interacting Protein 1 NR box II Peptide | | 分子名称: | (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL, CHLORIDE ION, ESTROGEN RECEPTOR, ... | | 著者 | Shiau, A.K, Barstad, D, Radek, J.T, Meyers, M.J, Nettles, K.W, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Agard, D.A, Greene, G.L. | | 登録日 | 2002-02-21 | | 公開日 | 2002-05-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
Nat.Struct.Biol., 9, 2002
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1LPE
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3ERD
 | | HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DIETHYLSTILBESTROL AND A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE | | 分子名称: | ACETIC ACID, CHLORIDE ION, DIETHYLSTILBESTROL, ... | | 著者 | Shiau, A.K, Barstad, D, Loria, P.M, Cheng, L, Kushner, P.J, Agard, D.A, Greene, G.L. | | 登録日 | 1999-03-31 | | 公開日 | 1999-04-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen.
Cell(Cambridge,Mass.), 95, 1998
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3ERT
 | | HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH 4-HYDROXYTAMOXIFEN | | 分子名称: | 4-HYDROXYTAMOXIFEN, PROTEIN (ESTROGEN RECEPTOR ALPHA) | | 著者 | Shiau, A.K, Barstad, D, Loria, P.M, Cheng, L, Kushner, P.J, Agard, D.A, Greene, G.L. | | 登録日 | 1999-03-30 | | 公開日 | 1999-04-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen.
Cell(Cambridge,Mass.), 95, 1998
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1SF8
 | | Crystal structure of the carboxy-terminal domain of htpG, the E. coli Hsp90 | | 分子名称: | CHLORIDE ION, Chaperone protein htpG, NICKEL (II) ION | | 著者 | Harris, S.F, Shiau, A.K, Agard, D.A. | | 登録日 | 2004-02-19 | | 公開日 | 2004-06-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of the carboxy-terminal dimerization domain of htpG, the Escherichia coli Hsp90, reveals a potential substrate binding site.
Structure, 12, 2004
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1SSX
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4IPE
 | | Crystal structure of mitochondrial Hsp90 (TRAP1) with AMPPNP | | 分子名称: | COBALT (II) ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Partridge, J.R, Lavery, L.A, Agard, D.A. | | 登録日 | 2013-01-09 | | 公開日 | 2014-01-22 | | 最終更新日 | 2014-08-27 | | 実験手法 | X-RAY DIFFRACTION (2.289 Å) | | 主引用文献 | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism.
Mol.Cell, 53, 2014
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4IVG
 | | Crystal structure of mitochondrial Hsp90 (TRAP1) NTD-Middle domain dimer with AMPPNP | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Partridge, J.R, Lavery, L.A, Agard, D.A. | | 登録日 | 2013-01-22 | | 公開日 | 2014-01-22 | | 最終更新日 | 2014-08-27 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism.
Mol.Cell, 53, 2014
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4IYN
 | | Structure of mitochondrial Hsp90 (TRAP1) with ADP-ALF4- | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, MAGNESIUM ION, ... | | 著者 | Partridge, J.R, Lavery, L.A, Agard, D.A. | | 登録日 | 2013-01-28 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.312 Å) | | 主引用文献 | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism.
Mol.Cell, 53, 2014
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4J0B
 | | Structure of mitochondrial Hsp90 (TRAP1) with ADP-BeF3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, COBALT (II) ION, ... | | 著者 | Partridge, J.R, Lavery, L.A, Agard, D.A. | | 登録日 | 2013-01-30 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.352 Å) | | 主引用文献 | Structural asymmetry in the closed state of mitochondrial Hsp90 (TRAP1) supports a two-step ATP hydrolysis mechanism.
Mol.Cell, 53, 2014
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