8OJ0
 
 | | 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | | 登録日 | 2023-03-23 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
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3OC3
 | | Crystal structure of the Mot1 N-terminal domain in complex with TBP | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HELICASE MOT1, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1) | | 著者 | Wollmann, P, Cui, S, Viswanathan, R, Berninghausen, O, Wells, M.N, Moldt, M, Witte, G, Butryn, A, Wendler, P, Beckmann, R, Auble, D.T, Hopfner, K.-P. | | 登録日 | 2010-08-09 | | 公開日 | 2011-07-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
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8BQX
 | | Yeast 80S ribosome in complex with Map1 (conformation 2) | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | 著者 | Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. | | 登録日 | 2022-11-21 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains.
Plos Biol., 21, 2023
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8BQD
 | | Yeast 80S ribosome in complex with Map1 (conformation 1) | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | 著者 | Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. | | 登録日 | 2022-11-21 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains.
Plos Biol., 21, 2023
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7QVP
 | | Human collided disome (di-ribosome) stalled on XBP1 mRNA | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Denk, T.G, Tesina, P, Beckmann, R. | | 登録日 | 2022-01-22 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
Nat Commun, 13, 2022
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6I7O
 | | The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition. | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Tesina, P, Cheng, J, Becker, T, Beckmann, R. | | 登録日 | 2018-11-16 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | | 主引用文献 | Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
EMBO J., 38, 2019
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8QPP
 | | Bacillus subtilis MutS2-collided disome complex (stalled 70S) | | 分子名称: | 16S rRNA (1533-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Park, E, Mackens-Kiani, T, Berhane, R, Esser, H, Erdenebat, C, Burroughs, A.M, Berninghausen, O, Aravind, L, Beckmann, R, Green, R, Buskirk, A.R. | | 登録日 | 2023-10-02 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage.
Embo J., 43, 2024
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8R55
 | | Bacillus subtilis MutS2-collided disome complex (collided 70S) | | 分子名称: | 16S rRNA (1533-MER), 23S RNA (2887-MER), 30S ribosomal protein S10, ... | | 著者 | Park, E, Mackens-Kiani, T, Berhane, R, Esser, H, Erdenebat, C, Burroughs, A.M, Berninghausen, O, Aravind, L, Beckmann, R, Green, R, Buskirk, A.R. | | 登録日 | 2023-11-16 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | | 主引用文献 | B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage.
Embo J., 43, 2024
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6HD5
 | | Cryo-EM structure of the ribosome-NatA complex | | 分子名称: | N-alpha-acetyltransferase NAT5, N-terminal acetyltransferase A complex catalytic subunit ARD1, N-terminal acetyltransferase A complex subunit NAT1 | | 著者 | Knorr, A.G, Becker, T, Beckmann, R. | | 登録日 | 2018-08-17 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Ribosome-NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation.
Nat. Struct. Mol. Biol., 26, 2019
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2WWB
 | | CRYO-EM STRUCTURE OF THE MAMMALIAN SEC61 COMPLEX BOUND TO THE ACTIVELY TRANSLATING WHEAT GERM 80S RIBOSOME | | 分子名称: | 25S RRNA, 5.8S RRNA, 60S RIBOSOMAL PROTEIN L17-A, ... | | 著者 | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | | 登録日 | 2009-10-22 | | 公開日 | 2009-12-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (6.48 Å) | | 主引用文献 | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Science, 326, 2009
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2WW9
 | | Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome | | 分子名称: | 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... | | 著者 | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | | 登録日 | 2009-10-22 | | 公開日 | 2009-12-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | | 主引用文献 | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Science, 326, 2009
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2WWA
 | | Cryo-EM structure of idle yeast Ssh1 complex bound to the yeast 80S ribosome | | 分子名称: | 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... | | 著者 | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | | 登録日 | 2009-10-22 | | 公開日 | 2009-12-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | | 主引用文献 | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Science, 326, 2009
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5LW7
 | | S. solfataricus ABCE1 post-splitting state | | 分子名称: | ABC transporter ATP-binding protein, IRON/SULFUR CLUSTER | | 著者 | Heuer, A, Gerovac, M, Beckmann, R, Tampe, R. | | 登録日 | 2016-09-15 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (17 Å) | | 主引用文献 | Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry.
Nat Commun, 7, 2016
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5M5H
 | | RIBOSOME-BOUND YIDC INSERTASE | | 分子名称: | Membrane protein insertase YidC | | 著者 | Kedrov, A, Wickles, S, Crevenna, A.H, van der Sluis, E, Buschauer, R, Berninghausen, O, Lamb, D.C, Beckmann, R. | | 登録日 | 2016-10-21 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural Dynamics of the YidC:Ribosome Complex during Membrane Protein Biogenesis.
Cell Rep, 17, 2016
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5LL6
 | | Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation initiation | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Heuer, A, Gerovac, M, Schmidt, C, Trowitzsch, S, Preis, A, Koetter, P, Berninghausen, O, Becker, T, Beckmann, R, Tampe, R. | | 登録日 | 2016-07-26 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation.
Nat. Struct. Mol. Biol., 24, 2017
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9GY4
 | | 60S ribosomal subunit in complex with E3-UFM1 ligase and RQC machinery components NEMF and LTN1 (Composite map) | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Penchev, I, Gumbin, S, Becker, T, Kopito, R, Beckmann, R. | | 登録日 | 2024-10-01 | | 公開日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | UFMylation orchestrates spatiotemporal coordination of RQC at the ER.
Sci Adv, 11, 2025
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3IZD
 | | Model of the large subunit RNA expansion segment ES27L-out based on a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome. 3IZD is a small part (an expansion segment) which is in an alternative conformation to what is in already 3IZF. | | 分子名称: | rRNA expansion segment ES27L in an "out" conformation | | 著者 | Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. | | 登録日 | 2010-10-13 | | 公開日 | 2010-12-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | | 主引用文献 | Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
Proc.Natl.Acad.Sci.USA, 107, 2010
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1G61
 | | CRYSTAL STRUCTURE OF M.JANNASCHII EIF6 | | 分子名称: | TRANSLATION INITIATION FACTOR 6 | | 著者 | Groft, C.M, Beckmann, R, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2000-11-02 | | 公開日 | 2000-11-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structures of ribosome anti-association factor IF6.
Nat.Struct.Biol., 7, 2000
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4CRN
 | | Cryo-EM of a pretermination complex with eRF1 and eRF3 | | 分子名称: | ERF1 IN RIBOSOME-BOUND ERF1-ERF3-GDPNP COMPLEX, ERF3 IN RIBOSOME BOUND ERF1-ERF3-GDPNP COMPLEX, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | 著者 | Preis, A, Heuer, A, Barrio-Garcia, C, Hauser, A, Eyler, D, Berninghausen, O, Green, R, Becker, T, Beckmann, R. | | 登録日 | 2014-02-28 | | 公開日 | 2014-07-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | | 主引用文献 | Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing Erf1-Erf3 or Erf1-Abce1.
Cell Rep., 8, 2014
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1G62
 | | CRYSTAL STRUCTURE OF S.CEREVISIAE EIF6 | | 分子名称: | RIBOSOME ANTI-ASSOCIATION FACTOR EIF6 | | 著者 | Groft, C.M, Beckmann, R, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2000-11-02 | | 公開日 | 2000-11-22 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of ribosome anti-association factor IF6.
Nat.Struct.Biol., 7, 2000
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4CRM
 | | Cryo-EM of a pre-recycling complex with eRF1 and ABCE1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1, ... | | 著者 | Preis, A, Heuer, A, Barrio-Garcia, C, Hauser, A, Eyler, D, Berninghausen, O, Green, R, Becker, T, Beckmann, R. | | 登録日 | 2014-02-28 | | 公開日 | 2014-07-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (8.75 Å) | | 主引用文献 | Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing Erf1-Erf3 or Erf1-Abce1.
Cell Rep., 8, 2014
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4UE4
 | | Structural basis for targeting and elongation arrest of Bacillus signal recognition particle | | 分子名称: | 6S RNA, FTSQ SIGNAL SEQUENCE, SIGNAL RECOGNITION PARTICLE PROTEIN | | 著者 | Beckert, B, Kedrov, A, Sohmen, D, Kempf, G, Wild, K, Sinning, I, Stahlberg, H, Wilson, D.N, Beckmann, R. | | 登録日 | 2014-12-15 | | 公開日 | 2015-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Translational Arrest by a Prokaryotic Signal Recognition Particle is Mediated by RNA Interactions.
Nat.Struct.Mol.Biol., 22, 2015
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4UE5
 | | Structural basis for targeting and elongation arrest of Bacillus signal recognition particle | | 分子名称: | 7S RNA, SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN, SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN, ... | | 著者 | Beckert, B, Kedrov, A, Sohmen, D, Kempf, G, Wild, K, Sinning, I, Stahlberg, H, Wilson, D.N, Beckmann, R. | | 登録日 | 2014-12-15 | | 公開日 | 2015-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Translational Arrest by a Prokaryotic Signal Recognition Particle is Mediated by RNA Interactions.
Nat.Struct.Mol.Biol., 22, 2015
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4V7F
 | | Arx1 pre-60S particle. | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Leidig, C, Thoms, M, Holdermann, I, Bradatsch, B, Berninghausen, O, Bange, G, Sinning, I, Hurt, E, Beckmann, R. | | 登録日 | 2013-12-10 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | | 主引用文献 | 60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle.
Nat Commun, 5, 2014
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4UTQ
 | | A structural model of the active ribosome-bound membrane protein insertase YidC | | 分子名称: | ATP SYNTHASE SUBUNIT C, MEMBRANE PROTEIN INSERTASE YIDC | | 著者 | Wickles, S, Singharoy, A, Andreani, J, Seemayer, S, Bischoff, L, Berninghausen, O, Soeding, J, Schulten, K, vanderSluis, E.O, Beckmann, R. | | 登録日 | 2014-07-22 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | A Structural Model of the Active Ribosome-Bound Membrane Protein Insertase Yidc.
Elife, 3, 2014
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