1A8H
 
 | | METHIONYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS | | 分子名称: | METHIONYL-TRNA SYNTHETASE, ZINC ION | | 著者 | Sugiura, I, Nureki, O, Ugaji, Y, Kuwabara, S, Lober, B, Giege, R, Moras, D, Yokoyama, S, Konno, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 1998-03-26 | | 公開日 | 1999-05-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The 2.0 A crystal structure of Thermus thermophilus methionyl-tRNA synthetase reveals two RNA-binding modules.
Structure, 8, 2000
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3L6N
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2MEF
 | | CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 1998-05-04 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of amino acid substitutions at two different interior positions to the conformational stability of human lysozyme
Protein Eng., 12, 1999
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3VUC
 | | Human renin in complex with compound 5 | | 分子名称: | (2R,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-2-ethyl-4-hydroxy-N-[(1R,2S,3S,5S,7S)-5-hydroxytricyclo[3.3.1.1~3,7~]dec-2-yl]hexanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin | | 著者 | Takahashi, M, Matsui, Y, Hanzawa, H. | | 登録日 | 2012-06-26 | | 公開日 | 2013-05-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor.
Acs Med.Chem.Lett., 3, 2012
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2MEG
 | | CHANGES IN CONFORMATIONAL STABILITY OF A SERIES OF MUTANT HUMAN LYSOZYMES AT CONSTANT POSITIONS. | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 1998-05-02 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of amino acid substitutions at two different interior positions to the conformational stability of human lysozyme
Protein Eng., 12, 1999
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2MEE
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6IO0
 | | Human IDH1 R132C mutant complexed with compound A. | | 分子名称: | (2E)-3-{3-[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazole-4-carbonyl]-1-methyl-1H-indol-7-yl}prop-2-enoic acid, CITRIC ACID, GLYCEROL, ... | | 著者 | Suzuki, M, Baba, D, Hanzawa, H. | | 登録日 | 2018-10-29 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model.
Mol.Cancer Ther., 19, 2020
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2MEB
 | | CHANGES IN CONFORMATIONAL STABILITY OF A SERIES OF MUTANT HUMAN LYSOZYMES AT CONSTANT POSITIONS | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 1998-05-02 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of amino acid substitutions at two different interior positions to the conformational stability of human lysozyme
Protein Eng., 12, 1999
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2MEC
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2MEI
 | | CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 1998-05-02 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of amino acid substitutions at two different interior positions to the conformational stability of human lysozyme
Protein Eng., 12, 1999
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2MEH
 | | CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 1998-05-02 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of amino acid substitutions at two different interior positions to the conformational stability of human lysozyme
Protein Eng., 12, 1999
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2MED
 | | CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 1998-05-02 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Contribution of amino acid substitutions at two different interior positions to the conformational stability of human lysozyme
Protein Eng., 12, 1999
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2MEA
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6IJY
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7V4F
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3TZ1
 | | Crystal structure of the Ca2+-saturated C-terminal domain of Akazara scallop troponin C in complex with a troponin I fragment | | 分子名称: | CALCIUM ION, Troponin C, Troponin I | | 著者 | Yumoto, F, Kato, Y.S, Ohtsuki, I, Tanokura, M. | | 登録日 | 2011-09-26 | | 公開日 | 2013-01-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of the Ca2+-saturated C-terminal domain of scallop troponin C in complex with a troponin I fragment
Biol.Chem., 394, 2012
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3RCD
 | | HER2 Kinase Domain Complexed with TAK-285 | | 分子名称: | N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide, Receptor tyrosine-protein kinase erbB-2 | | 著者 | Aertgeerts, K, Skene, R, Sogabe, S. | | 登録日 | 2011-03-30 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-d]pyrimidine Scaffold.
J.Med.Chem., 54, 2011
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1N7K
 | | Unique tetrameric structure of deoxyribose phosphate aldolase from Aeropyrum pernix | | 分子名称: | deoxyribose-phosphate aldolase | | 著者 | Tsuge, H, Sakuraba, H, Shimoya, I, Katunuma, N, Ago, H, Miyano, M, Ohshima, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2002-11-15 | | 公開日 | 2003-03-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The First Crystal Structure of Archaeal Aldolase. UNIQUE TETRAMERIC STRUCTURE of 2-DEOXY-D-RIBOSE-5-PHOSPHATE ALDOLASE FROM THE HYPERTHERMOPHILIC ARCHAEA Aeropyrum pernix.
J.Biol.Chem., 278, 2003
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7EBT
 | | Crystal structure of Aedes aegypti Noppera-bo, glutathione S-transferase epsilon 8, in glutathione-bound form | | 分子名称: | CALCIUM ION, GLUTATHIONE, Glutathione transferase | | 著者 | Inaba, K, Koiwai, K, Senda, M, Senda, T, Niwa, R. | | 登録日 | 2021-03-11 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
Bmc Biol., 20, 2022
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7EBW
 | | Crystal structure of Aedes aegypti Noppera-bo, glutathione S-transferase epsilon 8, in desmethylglycitein and glutathione-bound form | | 分子名称: | 6,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, CALCIUM ION, GLUTATHIONE, ... | | 著者 | Inaba, K, Koiwai, K, Senda, M, Senda, T, Niwa, R. | | 登録日 | 2021-03-11 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
Bmc Biol., 20, 2022
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7EBV
 | | Crystal structure of Aedes aegypti Noppera-bo, glutathione S-transferase epsilon 8, in luteolin- and glutathione-bound form | | 分子名称: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, CALCIUM ION, GLUTATHIONE, ... | | 著者 | Inaba, K, Koiwai, K, Senda, M, Senda, T, Niwa, R. | | 登録日 | 2021-03-11 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
Bmc Biol., 20, 2022
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7EBU
 | | Crystal structure of Aedes aegypti Noppera-bo, glutathione S-transferase epsilon 8, in Daidzein- and glutathione-bound form | | 分子名称: | 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, CALCIUM ION, GLUTATHIONE, ... | | 著者 | Inaba, K, Koiwai, K, Senda, M, Senda, T, Niwa, R. | | 登録日 | 2021-03-11 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
Bmc Biol., 20, 2022
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1ECS
 | | THE 1.7 A CRYSTAL STRUCTURE OF A BLEOMYCIN RESISTANCE DETERMINANT ENCODED ON THE TRANSPOSON TN5 | | 分子名称: | BLEOMYCIN RESISTANCE PROTEIN, CALCIUM ION, TETRAETHYLENE GLYCOL | | 著者 | Maruyama, M, Matoba, Y, Kumagai, T, Sugiyama, M. | | 登録日 | 2000-01-25 | | 公開日 | 2001-05-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of the transposon Tn5-carried bleomycin resistance determinant uncomplexed and complexed with bleomycin.
J.Biol.Chem., 276, 2001
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3VKX
 | | Structure of PCNA | | 分子名称: | 3,5,3'TRIIODOTHYRONINE, CHLORIDE ION, Proliferating cell nuclear antigen, ... | | 著者 | Hashimoto, H, Hishiki, A, Shimizu, T, Sato, M, Punchihewa, C, Connelly, M, Actis, M, Waddell, B, Pagala, V, Fujii, N. | | 登録日 | 2011-11-26 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication
J.Biol.Chem., 287, 2012
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8D0Z
 | | S728-1157 IgG in complex with SARS-CoV-2-6P-Mut7 Spike protein (focused refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S728-1157 Fab heavy chain variable region, S728-1157 Fab light chain variable region, ... | | 著者 | Ozorowski, G, Torres, J.L, Ward, A.B. | | 登録日 | 2022-05-26 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants.
J.Clin.Invest., 133, 2023
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