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6J1N
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BU of 6j1n by Molmil
Anisodus acutangulus type III polyketide sythase AaPKS2 in complex with 4-carboxy-3-oxobutanoyl-CoA
分子名称: (3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,19,21-tetraoxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide (non-preferred name), A. acutangulus PKS2
著者Fang, C.L, Zhang, Y.
登録日2018-12-28
公開日2019-09-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.532 Å)
主引用文献Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation.
Nat Commun, 10, 2019
6JGF
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BU of 6jgf by Molmil
Crystal structure of Se-Met CadR from P. putida with a 21 residue C-terminal truncation
分子名称: CadR, PHOSPHATE ION
著者Liu, X.C, Gan, J.H, Chen, H.
登録日2019-02-13
公開日2019-09-25
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Selective cadmium regulation mediated by a cooperative binding mechanism in CadR.
Proc.Natl.Acad.Sci.USA, 116, 2019
6JGV
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BU of 6jgv by Molmil
Crystal structure of the transcriptional regulator CadR from P. putida
分子名称: CadR
著者Liu, X.C, Gan, J.H, Chen, H.
登録日2019-02-15
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Selective cadmium regulation mediated by a cooperative binding mechanism in CadR.
Proc.Natl.Acad.Sci.USA, 116, 2019
6JGX
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BU of 6jgx by Molmil
Crystal structure of the transcriptional regulator CadR from P. putida in complex with Cadmium(II) and DNA
分子名称: CADMIUM ION, CadR, DNA (5'-D(*CP*AP*CP*CP*CP*TP*AP*TP*AP*GP*TP*GP*GP*CP*TP*AP*CP*AP*GP*GP*GP*T)-3'), ...
著者Liu, X.C, Gan, J.H, Chen, H.
登録日2019-02-15
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Selective cadmium regulation mediated by a cooperative binding mechanism in CadR.
Proc.Natl.Acad.Sci.USA, 116, 2019
6JGW
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BU of 6jgw by Molmil
Crystal structure of the transcriptional regulator CadR from P. putida in complex with DNA
分子名称: CadR, DNA (27-MER)
著者Liu, X.C, Gan, J.H, Chen, H.
登録日2019-02-15
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Selective cadmium regulation mediated by a cooperative binding mechanism in CadR.
Proc.Natl.Acad.Sci.USA, 116, 2019
3BYT
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BU of 3byt by Molmil
A complex between a variant of staphylococcal enterotoxin C3 and the variable domain of the murine T cell receptor beta chain 8.2
分子名称: Enterotoxin type C-3, T cell receptor beta chain 8.2
著者Cho, S, Eric, J.S.
登録日2008-01-16
公開日2009-05-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
To be Published
3BVZ
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BU of 3bvz by Molmil
Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
分子名称: Enterotoxin type C-3, ZINC ION
著者Cho, S.
登録日2008-01-07
公開日2009-05-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex
To be Published
2ZI0
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BU of 2zi0 by Molmil
Crystal structure of Tav2b/siRNA complex
分子名称: Protein 2b, RNA (5'-D(P*AP*GP*AP*CP*AP*GP*CP*AP*UP*UP*AP*UP*GP*CP*UP*GP*UP*CP*UP*UP*U)-3')
著者Yuan, Y.A, Chen, H.-Y.
登録日2008-02-12
公開日2008-07-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural basis for RNA-silencing suppression by Tomato aspermy virus protein 2b
Embo Rep., 9, 2008
7F2B
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BU of 7f2b by Molmil
Crystal structure of SARS-CoV-2 nucleocapsid protein C-terminal RNA binding domain at 2.0A resolution
分子名称: CHLORIDE ION, Nucleoprotein, PHOSPHATE ION
著者Liu, C, Chen, Y.W.
登録日2021-06-10
公開日2021-09-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the SARS-CoV-2 nucleocapsid protein C-terminal domain and development of nucleocapsid-targeting nanobodies.
Febs J., 289, 2022
7F2E
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BU of 7f2e by Molmil
SARS-CoV-2 nucleocapsid protein C-terminal domain (dodecamer)
分子名称: Nucleoprotein, PHOSPHATE ION
著者Liu, C, Jiang, H.
登録日2021-06-10
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of the SARS-CoV-2 nucleocapsid protein C-terminal domain and development of nucleocapsid-targeting nanobodies.
Febs J., 289, 2022
8E4C
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BU of 8e4c by Molmil
IgM BCR fab truncated form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell antigen receptor complex-associated protein alpha chain,Yellow fluorescent protein, B-cell antigen receptor complex-associated protein beta chain, ...
著者Dong, Y, Pi, X, Wu, H, Reth, M.
登録日2022-08-18
公開日2022-11-16
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural principles of B cell antigen receptor assembly.
Nature, 612, 2022
8E3D
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BU of 8e3d by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#11)
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*TP*TP*TP*GP*GP*GP*GP*AP*GP*GP*GP*GP*TP*CP*TP*TP*TP*AP*AP*CP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*AP*AP*AP*GP*AP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*AP*AP*T)-3'), ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2022-08-17
公開日2023-02-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
8E3E
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BU of 8e3e by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing CAST sequence (#10)
分子名称: DNA (5'-D(*CP*TP*TP*TP*GP*GP*GP*GP*AP*GP*GP*GP*GP*TP*CP*TP*TP*TP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*AP*AP*AP*GP*AP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*AP*A)-3'), ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2022-08-17
公開日2023-02-08
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
8EMA
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BU of 8ema by Molmil
mouse full length B cell receptor
分子名称: Anti-human Langerin 2G3 lambda chain, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein beta chain, ...
著者Ying, D, Xiong, P, Michael, R.
登録日2022-09-27
公開日2022-11-16
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献Structural principles of B cell antigen receptor assembly.
Nature, 612, 2022
8C0P
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BU of 8c0p by Molmil
Crystal structure of S. aureus BlaR1 sensor domain in complex with a boronate inhibitor
分子名称: Regulatory protein BlaR1, [1-[[2,4-bis(trifluoromethyl)phenyl]methyl]benzimidazol-2-yl]sulfanylmethyl-$l^{3}-oxidanyl-bis(oxidanyl)boron
著者Miguel-Ruano, V, Jimenez-Faraco, E, Hermoso, J.A.
登録日2022-12-19
公開日2024-07-10
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Restoring susceptibility to beta-lactam antibiotics in methicillin-resistant Staphylococcus aureus.
Nat.Chem.Biol., 2024
8C0S
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BU of 8c0s by Molmil
Crystal structure of S. aureus BlaR1 sensor domain in complex with an imidazole inhibitor
分子名称: 3-[[2,4-bis(trifluoromethyl)phenyl]methyl]-5-(hydroxymethyl)-1~{H}-imidazole-2-thione, Regulatory protein BlaR1
著者Miguel-Ruano, V, Hermoso, J.A.
登録日2022-12-19
公開日2024-07-10
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Restoring susceptibility to beta-lactam antibiotics in methicillin-resistant Staphylococcus aureus.
Nat.Chem.Biol., 2024
8CF3
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BU of 8cf3 by Molmil
Crystal structure of S. aureus BlaR1 sensor domain in complex with cefepime
分子名称: Cefepime (open), Regulatory protein BlaR1
著者Miguel-Ruano, V, Hermoso, J.A.
登録日2023-02-02
公開日2024-09-04
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Restoring susceptibility to beta-lactam antibiotics in methicillin-resistant Staphylococcus aureus.
Nat.Chem.Biol., 2024
7JM5
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BU of 7jm5 by Molmil
Crystal structure of KDM4B in complex with QC6352
分子名称: 3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid, Lysine-specific demethylase 4B, NICKEL (II) ION, ...
著者White, S.W, Yun, M.
登録日2020-07-31
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma.
Sci Transl Med, 14, 2022
6KC0
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BU of 6kc0 by Molmil
fused To-MtbCsm1 with 2ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A),CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), MAGNESIUM ION
著者Li, T, Huo, Y, Jiang, T.
登録日2019-06-26
公開日2020-07-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.295 Å)
主引用文献Mycobacterium tuberculosis CRISPR/Cas system Csm1 holds clues to the evolutionary relationship between DNA polymerase and cyclase activity.
Int.J.Biol.Macromol., 170, 2020
6KTO
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BU of 6kto by Molmil
Crystal structure of human SHLD3-C-REV7-O-REV7-SHLD2 complex
分子名称: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2, Shieldin complex subunit 3
著者Liang, L, Yin, Y.
登録日2019-08-28
公開日2020-04-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.4497633 Å)
主引用文献Molecular basis for assembly of the shieldin complex and its implications for NHEJ.
Nat Commun, 11, 2020
7CO3
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BU of 7co3 by Molmil
HtrA-type protease AlgWS227A with tripeptide
分子名称: AlgW protein, TRP-VAL-PHE
著者Li, T, Song, Y.J, Bao, R.
登録日2020-08-03
公開日2021-03-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa.
Mbio, 12, 2021
7CO2
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BU of 7co2 by Molmil
HtrA-type protease AlgW with tripeptide
分子名称: AlgW protein, IMIDAZOLE, TRP-VAL-PHE
著者Li, T, Song, Y.J, Bao, R.
登録日2020-08-03
公開日2021-03-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa.
Mbio, 12, 2021
7CO7
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BU of 7co7 by Molmil
HtrA-type protease AlgWS227A with decapeptide
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, AlgW protein, decapeptide SVRDELRWVF
著者Li, T, Song, Y.J, Bao, R.
登録日2020-08-04
公開日2021-03-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa.
Mbio, 12, 2021
7CO5
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BU of 7co5 by Molmil
HtrA-type protease AlgW with decapeptide
分子名称: AlgW protein, IMIDAZOLE, decapeptide SVRDELRWVF
著者Li, T, Song, Y.J, Bao, R.
登録日2020-08-03
公開日2021-03-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.345 Å)
主引用文献Molecular Basis of the Versatile Regulatory Mechanism of HtrA-Type Protease AlgW from Pseudomonas aeruginosa.
Mbio, 12, 2021
6LDF
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BU of 6ldf by Molmil
Crystal structure of the Zn-directed tetramer of the engineered cyt cb 562 variant, C96K AB5
分子名称: CHLORIDE ION, HEME C, ZINC ION, ...
著者Song, W.J, Yu, J.
登録日2019-11-21
公開日2021-03-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Symmetry-related residues as promising hotspots for the evolution of de novo oligomeric enzymes.
Chem Sci, 12, 2021

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