1OBW
 
 | | STRUCTURE OF INORGANIC PYROPHOSPHATASE | | 分子名称: | INORGANIC PYROPHOSPHATASE, MAGNESIUM ION | | 著者 | Oganessyan, V.Yu, Harutyunyan, E.H, Avaeva, S.M, Oganessyan, N.N, Mather, T, Huber, R. | | 登録日 | 1996-10-09 | | 公開日 | 1997-09-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of holo inorganic pyrophosphatase from Escherichia coli at 1.9 A resolution. Mechanism of hydrolysis.
Biochemistry, 36, 1997
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8OET
 | | SFX structure of the class II photolyase complexed with a thymine dimer | | 分子名称: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, DNA (14-mer), Deoxyribodipyrimidine photo-lyase, ... | | 著者 | Lane, T.J, Christou, N.-E, Melo, D.V.M, Apostolopoulou, V, Pateras, A, Mashhour, A.R, Galchenkova, M, Gunther, S, Reinke, P, Kremling, V, Oberthuer, D, Henkel, A, Sprenger, J, Scheer, T.E.S, Lange, E, Yefanov, O.N, Middendorf, P, Sellberg, J.A, Schubert, R, Fadini, A, Cirelli, C, Beale, E.V, Johnson, P, Dworkowski, F, Ozerov, D, Bertrand, Q, Wranik, M, Zitter, E.D, Turk, D, Bajt, S, Chapman, H, Bacellar, C. | | 登録日 | 2023-03-12 | | 公開日 | 2023-11-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Time-resolved crystallography captures light-driven DNA repair.
Science, 382, 2023
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1Q8W
 | | The Catalytic Subunit of cAMP-dependent Protein Kinase in Complex with Rho-kinase Inhibitor Fasudil (HA-1077) | | 分子名称: | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, cAMP-dependent protein kinase inhibitor, alpha form, ... | | 著者 | Breitenlechner, C, Gassel, M, Hidaka, H, Kinzel, V, Huber, R, Engh, R.A, Bossemeyer, D. | | 登録日 | 2003-08-22 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity.
Structure, 11, 2003
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8PSV
 | | 2.7 A cryo-EM structure of in vitro assembled type 1 pilus rod | | 分子名称: | Type-1 fimbrial protein, A chain | | 著者 | Hospenthal, M, Zyla, D, Glockshuber, R, Waksman, G. | | 登録日 | 2023-07-13 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili.
Nat Commun, 15, 2024
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1HOE
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1Q8U
 | | The Catalytic Subunit of cAMP-dependent Protein Kinase in Complex with Rho-kinase Inhibitor H-1152P | | 分子名称: | (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE, N-OCTANOYL-N-METHYLGLUCAMINE, cAMP-dependent protein kinase inhibitor, ... | | 著者 | Breitenlechner, C, Gassel, M, Hidaka, H, Kinzel, V, Huber, R, Engh, R.A, Bossemeyer, D. | | 登録日 | 2003-08-22 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity.
Structure, 11, 2003
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1QGN
 | | CYSTATHIONINE GAMMA-SYNTHASE FROM NICOTIANA TABACUM | | 分子名称: | PROTEIN (CYSTATHIONINE GAMMA-SYNTHASE), PYRIDOXAL-5'-PHOSPHATE | | 著者 | Steegborn, C, Messerschmidt, A, Laber, B, Streber, W, Huber, R, Clausen, T. | | 登録日 | 1999-05-02 | | 公開日 | 1999-08-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The crystal structure of cystathionine gamma-synthase from Nicotiana tabacum reveals its substrate and reaction specificity.
J.Mol.Biol., 290, 1999
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1HLE
 | | CRYSTAL STRUCTURE OF CLEAVED EQUINE LEUCOCYTE ELASTASE INHIBITOR DETERMINED AT 1.95 ANGSTROMS RESOLUTION | | 分子名称: | CALCIUM ION, HORSE LEUKOCYTE ELASTASE INHIBITOR | | 著者 | Baumann, U, Bode, W, Huber, R, Travis, J, Potempa, J. | | 登録日 | 1992-04-13 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution.
J.Mol.Biol., 226, 1992
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1FFV
 | | CARBON MONOXIDE DEHYDROGENASE FROM HYDROGENOPHAGA PSEUDOFLAVA | | 分子名称: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), CUTL, MOLYBDOPROTEIN OF CARBON MONOXIDE DEHYDROGENASE, ... | | 著者 | Haenzelmann, P, Dobbek, H, Gremer, L, Huber, R, Meyer, O. | | 登録日 | 2000-07-26 | | 公開日 | 2000-09-15 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The effect of intracellular molybdenum in Hydrogenophaga pseudoflava on the crystallographic structure of the seleno-molybdo-iron-sulfur flavoenzyme carbon monoxide dehydrogenase.
J.Mol.Biol., 301, 2000
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1NAS
 | | SEPIAPTERIN REDUCTASE COMPLEXED WITH N-ACETYL SEROTONIN | | 分子名称: | N-ACETYL SEROTONIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OXALOACETATE ION, ... | | 著者 | Auerbach, G, Herrmann, A, Bacher, A, Huber, R. | | 登録日 | 1998-03-26 | | 公開日 | 1999-03-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters.
EMBO J., 16, 1997
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1PO9
 | | Crytsal structure of isoaspartyl dipeptidase | | 分子名称: | Isoaspartyl dipeptidase, ZINC ION | | 著者 | Jozic, D, Kaiser, J.T, Huber, R, Bode, W, Maskos, K. | | 登録日 | 2003-06-15 | | 公開日 | 2004-06-22 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray structure of isoaspartyl dipeptidase from E.coli: a dinuclear zinc peptidase evolved from amidohydrolases.
J.Mol.Biol., 332, 2003
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1POJ
 | | Isoaspartyl Dipeptidase with bound inhibitor | | 分子名称: | 2-{[[(1S)-1-AMINO-2-CARBOXYETHYL](DIHYDROXY)PHOSPHORANYL]METHYL}-4-METHYLPENTANOIC ACID, Isoaspartyl dipeptidase, ZINC ION | | 著者 | Jozic, D, Kaiser, J.T, Huber, R, Bode, W, Maskos, K. | | 登録日 | 2003-06-15 | | 公開日 | 2004-06-22 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | X-ray structure of isoaspartyl dipeptidase from E.coli: a dinuclear zinc peptidase evolved from amidohydrolases.
J.Mol.Biol., 332, 2003
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1POK
 | | Crystal structure of Isoaspartyl Dipeptidase | | 分子名称: | ASPARAGINE, Isoaspartyl dipeptidase, SULFATE ION, ... | | 著者 | Jozic, D, Kaiser, J.T, Huber, R, Bode, W, Maskos, K. | | 登録日 | 2003-06-15 | | 公開日 | 2004-06-22 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | X-ray structure of isoaspartyl dipeptidase from E.coli: a dinuclear zinc peptidase evolved from amidohydrolases.
J.Mol.Biol., 332, 2003
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1Q8T
 | | The Catalytic Subunit of cAMP-dependent Protein Kinase (PKA) in Complex with Rho-kinase Inhibitor Y-27632 | | 分子名称: | (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | | 著者 | Breitenlechner, C, Gassel, M, Hidaka, H, Kinzel, V, Huber, R, Engh, R.A, Bossemeyer, D. | | 登録日 | 2003-08-22 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity.
Structure, 11, 2003
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1PFX
 | | PORCINE FACTOR IXA | | 分子名称: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, FACTOR IXA | | 著者 | Brandstetter, H, Bauer, M, Huber, R, Lollar, P, Bode, W. | | 登録日 | 1995-07-19 | | 公開日 | 1996-08-17 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B.
Proc.Natl.Acad.Sci.USA, 92, 1995
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1FXY
 | | COAGULATION FACTOR XA-TRYPSIN CHIMERA INHIBITED WITH D-PHE-PRO-ARG-CHLOROMETHYLKETONE | | 分子名称: | COAGULATION FACTOR XA-TRYPSIN CHIMERA, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | | 著者 | Hopfner, K.P, Kopetzki, E, Kresse, G.-B, Huber, R, Bode, W, Engh, R.A. | | 登録日 | 1998-04-22 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | New enzyme lineages by subdomain shuffling.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1RFN
 | | HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE | | 分子名称: | CALCIUM ION, P-AMINO BENZAMIDINE, PROTEIN (COAGULATION FACTOR IX), ... | | 著者 | Hopfner, K.-P, Lang, A, Karcher, A, Sichler, K, Kopetzki, E, Brandstetter, H, Huber, R, Bode, W, Engh, R.A. | | 登録日 | 1999-04-19 | | 公開日 | 1999-09-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding.
Structure Fold.Des., 7, 1999
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1WQJ
 | | Structural Basis for the Regulation of Insulin-Like Growth Factors (IGFs) by IGF Binding Proteins (IGFBPs) | | 分子名称: | Insulin-like growth factor IB, Insulin-like growth factor binding protein 4 | | 著者 | Siwanowicz, I, Popowicz, G.M, Wisniewska, M, Huber, R, Kuenkele, K.P, Lang, K, Engh, R.A, Holak, T.A. | | 登録日 | 2004-09-29 | | 公開日 | 2005-03-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for the regulation of insulin-like growth factors by IGF binding proteins
Structure, 13, 2005
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1WYX
 | | The Crystal Structure of the p130Cas SH3 Domain at 1.1 A Resolution | | 分子名称: | 1,2-ETHANEDIOL, CRK-associated substrate, MAGNESIUM ION | | 著者 | Wisniewska, M, Bossenmaier, B, Georges, G, Hesse, F, Dangl, M, Kuenkele, K.P, Ioannidis, I, Huber, R, Engh, R.A. | | 登録日 | 2005-02-17 | | 公開日 | 2005-04-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | The 1.1 A resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity
J.Mol.Biol., 347, 2005
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1JFD
 | | STRUCTURE OF INORGANIC PYROPHOSPHATASE | | 分子名称: | INORGANIC PYROPHOSPHATASE, SULFATE ION | | 著者 | Oganesyan, V, Avaeva, S.M, Huber, R, Harutyunyan, E.H. | | 登録日 | 1997-05-31 | | 公開日 | 1997-12-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of Escherichia coli inorganic pyrophosphatase complexed with SO4(2-). Ligand-induced molecular asymmetry.
FEBS Lett., 410, 1997
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8RGX
 | | Cryo-EM structure of the Bacterial Proteasome Activator Bpa of Mycobacterium tuberculosis | | 分子名称: | Bacterial proteasome activator | | 著者 | Zdanowicz, R, von Rosen, T, Afanasyev, P, Boehringer, D, Glockshuber, R, Weber-Ban, E. | | 登録日 | 2023-12-14 | | 公開日 | 2025-04-02 | | 最終更新日 | 2025-04-09 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Substrates bind to residues lining the ring of asymmetrically engaged bacterial proteasome activator Bpa.
Nat Commun, 16, 2025
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1LTO
 | | Human alpha1-tryptase | | 分子名称: | alpha tryptase I | | 著者 | Marquardt, U, Zettl, F, Huber, R, Bode, W, Sommerhoff, C.P. | | 登録日 | 2002-05-20 | | 公開日 | 2003-05-20 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Crystal Structure of Human alpha1-Tryptase Reveals a Blocked Substrate-binding Region
J.MOL.BIOL., 321, 2002
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1YOM
 | | Crystal structure of Src kinase domain in complex with Purvalanol A | | 分子名称: | 2-({6-[(3-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)-3-METHYLBUTAN-1-OL, Proto-oncogene tyrosine-protein kinase Src | | 著者 | Breitenlechner, C.B, Kairies, N.A, Honold, K, Scheiblich, S, Koll, H, Greiter, E, Koch, S, Schaefer, W, Huber, R, Engh, R.A. | | 登録日 | 2005-01-27 | | 公開日 | 2006-01-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of active SRC kinase domain complexes
J.Mol.Biol., 353, 2005
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1ZLI
 | | Crystal structure of the tick carboxypeptidase inhibitor in complex with human carboxypeptidase B | | 分子名称: | Carboxypeptidase B, ZINC ION, carboxypeptidase inhibitor | | 著者 | Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A. | | 登録日 | 2005-05-06 | | 公開日 | 2005-07-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
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1LFW
 | | Crystal structure of pepV | | 分子名称: | 3-[(1-AMINO-2-CARBOXY-ETHYL)-HYDROXY-PHOSPHINOYL]-2-METHYL-PROPIONIC ACID, ZINC ION, pepV | | 著者 | Jozic, D, Bourenkow, G, Bartunik, H, Scholze, H, Dive, V, Henrich, B, Huber, R, Bode, W, Maskos, K. | | 登録日 | 2002-04-12 | | 公開日 | 2002-10-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of the Dinuclear Zinc Aminopeptidase PepV from Lactobacillus delbrueckii Unravels Its Preference for Dipeptides
Structure, 10, 2002
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