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4N88
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BU of 4n88 by Molmil
Crystal structure of Tse3-Tsi3 complex with calcium ion
分子名称: CALCIUM ION, Uncharacterized protein
著者Shang, G.J.
登録日2013-10-17
公開日2014-04-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
Mol.Microbiol., 92, 2014
6IGZ
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BU of 6igz by Molmil
Structure of PSI-LHCI
分子名称: (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (6'R,11cis,11'cis,13cis,15cis)-4',5'-didehydro-5',6'-dihydro-beta,beta-carotene, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
著者Xiong, P, Xiaochun, Q.
登録日2018-09-27
公開日2019-02-13
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structure of a green algal photosystem I in complex with a large number of light-harvesting complex I subunits.
Nat Plants, 5, 2019
4N80
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BU of 4n80 by Molmil
Crystal structure of Tse3-Tsi3 complex
分子名称: CALCIUM ION, Uncharacterized protein, ZINC ION
著者Shang, G.J.
登録日2013-10-16
公開日2014-04-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
Mol.Microbiol., 92, 2014
6JLU
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BU of 6jlu by Molmil
Structure of PSII-FCP supercomplex from a centric diatom Chaetoceros gracilis at 3.02 angstrom resolution
分子名称: (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ...
著者Pi, X, Zhao, S, Wang, W, Kuang, T, Sui, S, Shen, J.
登録日2019-03-06
公開日2019-07-31
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献The pigment-protein network of a diatom photosystem II-light-harvesting antenna supercomplex.
Science, 365, 2019
4N7S
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BU of 4n7s by Molmil
Crystal structure of Tse3-Tsi3 complex with Zinc ion
分子名称: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
著者Shang, G.J.
登録日2013-10-16
公開日2014-04-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
Mol.Microbiol., 92, 2014
3I81
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BU of 3i81 by Molmil
Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with BMS-754807 [1-(4-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-2-yl)-N-(6-fluoro-3-pyridinyl)-2-methyl-L-prolinamide]
分子名称: 1-{4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoropyridin-3-yl)-2-methyl-L-proli namide, Insulin-like growth factor 1 receptor
著者Sack, J.S.
登録日2009-07-09
公開日2009-12-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Discovery of a 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitor (BMS-754807) of insulin-like growth factor receptor (IGF-1R) kinase in clinical development.
J.Med.Chem., 52, 2009
5ZZD
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BU of 5zzd by Molmil
Crystal structure of a protein from Aspergillus flavus
分子名称: O-methyltransferase lepI, S-ADENOSYLMETHIONINE
著者Chang, Z.Y, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2018-05-31
公開日2019-06-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of LepI, a multifunctional SAM-dependent enzyme which catalyzes pericyclic reactions in leporin biosynthesis.
Org.Biomol.Chem., 17, 2019
7BY7
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BU of 7by7 by Molmil
Bacteriophage SPO1 protein Gp46
分子名称: Putative gene 46 protein
著者Liu, B, Zhang, P.
登録日2020-04-22
公開日2021-04-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Bacteriophage protein Gp46 is a cross-species inhibitor of nucleoid-associated HU proteins
Proc.Natl.Acad.Sci.USA, 119, 2022
5V80
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BU of 5v80 by Molmil
PIM1 kinase in complex with Cpd1 (1-methyl-4-(3-(6-(piperazin-1-yl)pyridin-2-yl)-1H-pyrazolo[3,4-c]pyridin-5-yl)piperazin-2-one)
分子名称: 1-methyl-4-{3-[6-(piperazin-1-yl)pyridin-2-yl]-1H-pyrazolo[3,4-c]pyridin-5-yl}piperazin-2-one, PHOSPHATE ION, Serine/threonine-protein kinase pim-1
著者Murray, J.M, Wallweber, H.
登録日2017-03-21
公開日2018-04-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.252 Å)
主引用文献Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized Bioavailability.
J. Med. Chem., 60, 2017
5V82
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BU of 5v82 by Molmil
PIM1 kinase in complex with Cpd17 (1-(6-(4,4-difluoropiperidin-3-yl)pyridin-2-yl)-6-(6-methylpyrazin-2-yl)-1H-pyrazolo[4,3-c]pyridine)
分子名称: 1-{6-[(3R)-4,4-difluoropiperidin-3-yl]pyridin-2-yl}-6-(6-methylpyrazin-2-yl)-1H-pyrazolo[4,3-c]pyridine, Serine/threonine-protein kinase pim-1
著者Murray, J.M, Wallweber, H.
登録日2017-03-21
公開日2017-05-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.888 Å)
主引用文献Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized Bioavailability.
J. Med. Chem., 60, 2017
4M5E
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BU of 4m5e by Molmil
Tse3 structure
分子名称: CADMIUM ION, CALCIUM ION, GLYCEROL, ...
著者Qian, Y.
登録日2013-08-08
公開日2014-04-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
Mol.Microbiol., 92, 2014
4M5F
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BU of 4m5f by Molmil
complex structure of Tse3-Tsi3
分子名称: CALCIUM ION, PHOSPHATE ION, Uncharacterized protein
著者Gu, L.C.
登録日2013-08-08
公開日2014-04-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
Mol.Microbiol., 92, 2014
2LUQ
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BU of 2luq by Molmil
Solution structure of double-stranded RNA binding domain of S.cerevisiae RNase III (rnt1p)
分子名称: Ribonuclease 3
著者Wang, Z, Feigon, J.
登録日2012-06-19
公開日2012-12-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Intrinsic Dynamics of an Extended Hydrophobic Core in the S. cerevisiae RNase III dsRBD Contributes to Recognition of Specific RNA Binding Sites.
J.Mol.Biol., 425, 2013
8JUL
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BU of 8jul by Molmil
Cryo-EM structure of SIDT1 in complex with phosphatidic acid
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, SID1 transmembrane family member 1, ZINC ION
著者Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y.
登録日2023-06-26
公開日2023-11-15
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Human SIDT1 mediates dsRNA uptake via its phospholipase activity.
Cell Res., 34, 2024
8JUN
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BU of 8jun by Molmil
Cryo-EM structure of SIDT1 E555Q mutant
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SID1 transmembrane family member 1, ZINC ION
著者Sun, C.R, Xu, D, Li, Q, Zhou, C.Z, Chen, Y.
登録日2023-06-26
公開日2023-11-15
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (2.38 Å)
主引用文献Human SIDT1 mediates dsRNA uptake via its phospholipase activity.
Cell Res., 34, 2024
8GPY
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BU of 8gpy by Molmil
Crystal structure of Omicron BA.4/5 RBD in complex with a neutralizing antibody scFv
分子名称: Spike protein S1, scFv
著者Gao, Y.X, Song, Z.D, Wang, W.M, Guo, Y.
登録日2022-08-27
公開日2023-06-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection.
Nat Commun, 14, 2023
8IK0
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BU of 8ik0 by Molmil
Cryo-EM structure of Stimulator of interferon genes
分子名称: Stimulator of interferon genes protein,Immune protein Tsi3
著者Lu, D.F, Shang, G.J.
登録日2023-02-28
公開日2023-05-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The mechanism of STING autoinhibition and activation.
Mol.Cell, 83, 2023
8IK3
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BU of 8ik3 by Molmil
Structure of Stimulator of interferon genes/ligand complex
分子名称: Stimulator of interferon genes protein,Immune protein Tsi3, cGAMP
著者Lu, D.F, Shang, G.J.
登録日2023-02-28
公開日2023-05-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The mechanism of STING autoinhibition and activation.
Mol.Cell, 83, 2023
4ZIM
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BU of 4zim by Molmil
CRYSTAL STRUCTURE OF JANUS KINASE 2 IN COMPLEX WITH A 9H-CARBAZOLE-1-CARBOXAMIDE INHIBITOR
分子名称: 3-(3,4-dichlorophenyl)-6-(morpholin-4-ylcarbonyl)-9H-carbazole-1-carboxamide, Tyrosine-protein kinase JAK2
著者Sack, J.S.
登録日2015-04-28
公開日2015-06-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
3FM9
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BU of 3fm9 by Molmil
Analysis of the Structural Determinants Underlying Discrimination between Substrate and Solvent in beta-Phosphoglucomutase Catalysis
分子名称: Beta-phosphoglucomutase, MAGNESIUM ION
著者Finci, L, Lahiri, S, Peisach, E, Allen, K.N.
登録日2008-12-19
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Analysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis.
Biochemistry, 48, 2009
7E0B
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BU of 7e0b by Molmil
The crystal structure of sorting nexin 27 and PBM complex
分子名称: PBM, Sorting nexin-27
著者Shang, G.J, Qi, J.X.
登録日2021-01-27
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献SNX27 suppresses SARS-CoV-2 infection by inhibiting viral lysosome/late endosome entry.
Proc.Natl.Acad.Sci.USA, 119, 2022
6LPA
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BU of 6lpa by Molmil
The nsp1 protein of a new porcine coronavirus
分子名称: sp1 protein
著者Shen, Z, Peng, G.Q.
登録日2020-01-09
公開日2020-08-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion.
Viruses, 12, 2020
7YJ3
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BU of 7yj3 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with human ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ...
著者Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F.
登録日2022-07-19
公開日2023-07-19
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023
7YV8
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BU of 7yv8 by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with golden hamster ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike glycoprotein, ...
著者Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F.
登録日2022-08-18
公開日2023-07-19
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023
7YVU
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BU of 7yvu by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with mouse ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1, ...
著者Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F.
登録日2022-08-19
公開日2023-07-19
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023

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