7MSM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7msm by Molmil](/molmil-images/mine/7msm) | |
2JXN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jxn by Molmil](/molmil-images/mine/2jxn) | Solution Structure of S. cerevisiae PDCD5-like Protein Ymr074cp | 分子名称: | S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, Uncharacterized protein YMR074C | 著者 | Hong, J, Zhang, J, Liu, Z, Shi, Y, Wu, J. | 登録日 | 2007-11-23 | 公開日 | 2008-12-02 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure and Dynamics of S. cerevisiae PDCD5-like Protein Ymr074cp Determined by Heteronuclear NMR Spectroscopy To be Published
|
|
8GXH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gxh by Molmil](/molmil-images/mine/8gxh) | The crystal structure of SARS-CoV-2 main protease in complex with 14b | 分子名称: | 3C-like proteinase nsp5, N-[(2S)-3-cyclohexyl-1-oxidanylidene-1-[[(2S,3R)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide | 著者 | Zhao, Y, Zhao, J, Shao, M, Yang, H, Rao, Z. | 登録日 | 2022-09-20 | 公開日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | The crystal structure of SARS-CoV-2 main protease in complex with 14b To Be Published
|
|
2L97
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l97 by Molmil](/molmil-images/mine/2l97) | |
8H91
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h91 by Molmil](/molmil-images/mine/8h91) | |
8HQG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hqg by Molmil](/molmil-images/mine/8hqg) | |
8HUW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8huw by Molmil](/molmil-images/mine/8huw) | Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with S217622 | 分子名称: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | 著者 | Wang, J, Zhang, J, Li, J. | 登録日 | 2022-12-24 | 公開日 | 2023-06-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir. Structure, 31, 2023
|
|
8HVM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hvm by Molmil](/molmil-images/mine/8hvm) | Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with PF07321332 | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | 著者 | Wang, J, Zhang, J, Li, J. | 登録日 | 2022-12-27 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
K90R mutant in complex with PF07321332 To Be Published
|
|
8HVU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hvu by Molmil](/molmil-images/mine/8hvu) | |
8HVV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hvv by Molmil](/molmil-images/mine/8hvv) | |
8HVX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hvx by Molmil](/molmil-images/mine/8hvx) | |
8HVY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hvy by Molmil](/molmil-images/mine/8hvy) | |
8IG4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ig4 by Molmil](/molmil-images/mine/8ig4) | |
8IG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ig5 by Molmil](/molmil-images/mine/8ig5) | Crystal structure of SARS main protease in complex with GC376 | 分子名称: | 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide | 著者 | Lin, C, Zhang, J, Li, J. | 登録日 | 2023-02-20 | 公開日 | 2024-03-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376. J.Mol.Biol., 436, 2024
|
|
8IG6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ig6 by Molmil](/molmil-images/mine/8ig6) | |
8IG8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ig8 by Molmil](/molmil-images/mine/8ig8) | |
8IG7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ig7 by Molmil](/molmil-images/mine/8ig7) | |
8IG9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ig9 by Molmil](/molmil-images/mine/8ig9) | |
8IGA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8iga by Molmil](/molmil-images/mine/8iga) | |
8IGB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8igb by Molmil](/molmil-images/mine/8igb) | |
4MSU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4msu by Molmil](/molmil-images/mine/4msu) | Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate | 分子名称: | 1,1,1,3,3,3-hexafluoro-2-{4-[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | 著者 | Ashton, K.S, Andrews, K.L, Bryan, M.C, Chen, J, Chen, K, Chen, M, Chmait, S, Croghan, M, Cupples, R, Fotsch, C, Helmering, J, Jordan, S.R, Kurzeja, R.J, Michelsen, K, Pennington, L.D, Poon, S.F, Sivits, G, Van, G, Vonderfecht, S.L, Wahl, R.C, Zhang, J, Lloyd, D.J, Hale, C, St Jean, D.J. | 登録日 | 2013-09-18 | 公開日 | 2014-03-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept. J.Med.Chem., 57, 2014
|
|
8GXI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gxi by Molmil](/molmil-images/mine/8gxi) | The crystal structure of SARS-CoV-2 main protease in complex with 14c | 分子名称: | 3C-like proteinase nsp5, N-[(2S)-3-cyclohexyl-1-[[(2S,3R)-4-(cyclopropylamino)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-benzofuran-2-carboxamide | 著者 | Zhao, Y, Zhao, J, Shao, M, Yang, H, Rao, Z. | 登録日 | 2022-09-20 | 公開日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | The crystal structure of SARS-CoV-2 main protease in complex with 14c To Be Published
|
|
8GXG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gxg by Molmil](/molmil-images/mine/8gxg) | The crystal structure of SARS-CoV-2 main protease in complex with 14a | 分子名称: | 3C-like proteinase nsp5, N-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide | 著者 | Zhao, Y, Zhao, J, Shao, M, Yang, H, Rao, Z. | 登録日 | 2022-09-20 | 公開日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | The crystal structure of SARS-CoV-2 main protease in complex with 14a To Be Published
|
|
6JPD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jpd by Molmil](/molmil-images/mine/6jpd) | Mouse receptor-interacting protein kinase 3 (RIP3) amyloid structure by solid-state NMR | 分子名称: | Receptor-interacting serine/threonine-protein kinase 3 | 著者 | Wu, X.L, Hu, H, Zhang, J, Dong, X.Q, Wang, J, Schwieters, C, Wang, H.Y, Lu, J.X. | 登録日 | 2019-03-26 | 公開日 | 2020-10-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | The amyloid structure of mouse RIPK3 (receptor interacting protein kinase 3) in cell necroptosis. Nat Commun, 12, 2021
|
|
4DWT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dwt by Molmil](/molmil-images/mine/4dwt) | |