Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1K6P
DownloadVisualize
BU of 1k6p by Molmil
LACK OF SYNERGY FOR INHIBITORS TARGETING A MULTI-DRUG RESISTANT HIV-1 PROTEASE
分子名称: ACETATE ION, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(BENZO[1,3]DIOXOL-5-YLMETHYL)-PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, POL polyprotein
著者Schiffer, C.A.
登録日2001-10-16
公開日2002-02-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lack of synergy for inhibitors targeting a multi-drug-resistant HIV-1 protease.
Protein Sci., 11, 2002
1PVD
DownloadVisualize
BU of 1pvd by Molmil
CRYSTAL STRUCTURE OF THE THIAMIN DIPHOSPHATE DEPENDENT ENZYME PYRUVATE DECARBOXYLASE FROM THE YEAST SACCHAROMYCES CEREVISIAE AT 2.3 ANGSTROMS RESOLUTION
分子名称: MAGNESIUM ION, PYRUVATE DECARBOXYLASE, THIAMINE DIPHOSPHATE
著者Furey, W, Arjunan, P.
登録日1995-04-20
公開日1995-07-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the thiamin diphosphate-dependent enzyme pyruvate decarboxylase from the yeast Saccharomyces cerevisiae at 2.3 A resolution.
J.Mol.Biol., 256, 1996
6AI8
DownloadVisualize
BU of 6ai8 by Molmil
Cab2 mutant-H337A
分子名称: GLYCEROL, Phosphopantothenate--cysteine ligase CAB2, SULFATE ION
著者Zheng, P, Zhu, Z.
登録日2018-08-22
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae.
J. Mol. Biol., 431, 2019
6AIP
DownloadVisualize
BU of 6aip by Molmil
Cab2 mutant-H337A complex with phosphopantothenoylcystine
分子名称: (5R,12R,17R)-17-amino-12-carboxy-1,1,5-trihydroxy-4,4-dimethyl-6,10-dioxo-2-oxa-14,15-dithia-7,11-diaza-1-phosphaoctadecan-18-oic acid 1-oxide (non-preferred name), Phosphopantothenate--cysteine ligase CAB2
著者Zheng, P, Zhu, Z.
登録日2018-08-24
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae.
J. Mol. Biol., 431, 2019
6AIK
DownloadVisualize
BU of 6aik by Molmil
Cab2 mutant H337A complex with phosphopantothenoyl-CMP
分子名称: PHOSPHORIC ACID MONO-[3-(3-{[5-(4-AMINO-2-OXO-2H-PYRIMIDIN-1-YL)-3,4- DIHYDROXY-TETRAHYDRO-FURAN-2- YLMETHOXY]-HYDROXY-PHOSPHORYLOXY}-3-OXO-PROPYLCARBAMOYL)-3-HYDROXY-2,2- DIMETHYL-PROPYL] ESTER, Phosphopantothenate--cysteine ligase CAB2
著者Zheng, P, Zhu, Z.
登録日2018-08-24
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae.
J. Mol. Biol., 431, 2019
4XVM
DownloadVisualize
BU of 4xvm by Molmil
Binary complex of human polymerase nu and DNA with the finger domain closed and thumb domain rotated out
分子名称: DNA (5'-D(*CP*TP*AP*GP*CP*GP*TP*CP*A)-3'), DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*G)-3'), DNA polymerase nu
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
4XVI
DownloadVisualize
BU of 4xvi by Molmil
Binary complex of human polymerase nu and DNA with the finger domain ajar
分子名称: DNA (5'-D(*AP*CP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*CP*AP*G)-3'), DNA polymerase nu
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
4XVK
DownloadVisualize
BU of 4xvk by Molmil
Binary complex of human polymerase nu and DNA with the finger domain closed
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ...
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
4XVL
DownloadVisualize
BU of 4xvl by Molmil
Binary complex of human polymerase nu and DNA with the finger domain open
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ...
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.301 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
7TIL
DownloadVisualize
BU of 7til by Molmil
CryoEM structure of JetD from Pseudomonas aeruginosa
分子名称: JetD
著者Deep, A, Gu, Y, Gao, Y, Ego, K, Herzik, M, Zhou, H, Corbett, K.
登録日2022-01-13
公開日2022-10-05
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The SMC-family Wadjet complex protects bacteria from plasmid transformation by recognition and cleavage of closed-circular DNA.
Mol.Cell, 82, 2022
7KID
DownloadVisualize
BU of 7kid by Molmil
PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 72
分子名称: (1S,2R,3aR,4S,6aR)-4-[(2-amino-3,5-difluoroquinolin-7-yl)methyl]-2-(4-amino-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)hexahydropentalene-1,6a(1H)-diol, 1,2-ETHANEDIOL, Methylosome protein 50, ...
著者Palte, R.L.
登録日2020-10-23
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer.
J.Med.Chem., 64, 2021
7KIC
DownloadVisualize
BU of 7kic by Molmil
PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 34
分子名称: (2R,3R,3aS,6S,6aR)-6-[(2-amino-3-bromoquinolin-7-yl)oxy]-2-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)hexahydro-3aH-cyclopenta[b]furan-3,3a-diol, 1,2-ETHANEDIOL, Methylosome protein 50, ...
著者Palte, R.L.
登録日2020-10-23
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer.
J.Med.Chem., 64, 2021
7KIB
DownloadVisualize
BU of 7kib by Molmil
PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 4
分子名称: (2R,3R,3aS,6S,6aR)-6-[(2-amino-3-bromoquinolin-7-yl)oxy]-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)hexahydro-3aH-cyclopenta[b]furan-3,3a-diol, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Palte, R.L, Hayes, R.P.
登録日2020-10-23
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer.
J.Med.Chem., 64, 2021
5A9Y
DownloadVisualize
BU of 5a9y by Molmil
Structure of ppGpp BipA
分子名称: GTP-BINDING PROTEIN, GUANOSINE-5',3'-TETRAPHOSPHATE
著者Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G.
登録日2015-07-23
公開日2015-08-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
6L77
DownloadVisualize
BU of 6l77 by Molmil
Crystal structure of MS5 from Brassica napus
分子名称: MS5a
著者Wang, X, Guan, Z.Y, Yin, P.
登録日2019-10-31
公開日2020-06-03
最終更新日2020-12-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of the meiosis-related protein MS5 reveals non-canonical papain enhancement by cystatin-like folds.
Febs Lett., 594, 2020
6LKC
DownloadVisualize
BU of 6lkc by Molmil
Crystal structure of PfaD from Shewanella piezotolerans in complex with FMN
分子名称: CALCIUM ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Zhang, M.L, Li, Q, Meng, S.S, Guo, L.J, He, L, Huang, J.Z, Li, L, Zhang, H.D.
登録日2019-12-19
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Structural Insights into the Trans -Acting Enoyl Reductase in the Biosynthesis of Long-Chain Polyunsaturated Fatty Acids in Shewanella piezotolerans .
J.Agric.Food Chem., 69, 2021
5A9Z
DownloadVisualize
BU of 5a9z by Molmil
Complex of Thermous thermophilus ribosome bound to BipA-GDPCP
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Kumar, V, Chen, Y, Ahmed, T, Tan, J, Ero, R, Bhushan, S, Gao, Y.-G.
登録日2015-07-23
公開日2015-10-14
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
5AA0
DownloadVisualize
BU of 5aa0 by Molmil
Complex of Thermous thermophilus ribosome (A-and P-site tRNA) bound to BipA-GDPCP
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
著者Kumar, V, Chen, Y, Ahmed, T, Tan, J, Ero, R, Bhushan, S, Gao, Y.-G.
登録日2015-07-23
公開日2015-10-14
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
2HDZ
DownloadVisualize
BU of 2hdz by Molmil
Crystal Structure Analysis of the UBF HMG box5
分子名称: Nucleolar transcription factor 1
著者Rong, H, Teng, M.K, Niu, L.W.
登録日2006-06-21
公開日2007-06-26
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of human upstream binding factor HMG box 5 and site for binding of the cell-cycle regulatory factor TAF1
Acta Crystallogr.,Sect.D, 63, 2007
2MBE
DownloadVisualize
BU of 2mbe by Molmil
Backbone 1H and 15N Chemical Shift Assignments for the first domain of FAT10
分子名称: Ubiquitin D
著者Wang, W, Lim, L, Qin, H.
登録日2013-07-30
公開日2014-08-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Disruption of FAT10-MAD2 binding inhibits tumor progression.
Proc.Natl.Acad.Sci.USA, 111, 2014
4LUQ
DownloadVisualize
BU of 4luq by Molmil
Crystal structure of virulence effector Tse3 in complex with neutralizer Tsi3
分子名称: CALCIUM ION, Uncharacterized protein
著者Wang, T, Li, L, Zhang, W.
登録日2013-07-25
公開日2013-09-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural Insights on the Bacteriolytic and Self-protection Mechanism of Muramidase Effector Tse3 in Pseudomonas aeruginosa
J.Biol.Chem., 288, 2013
3B9C
DownloadVisualize
BU of 3b9c by Molmil
Crystal Structure of Human GRP CRD
分子名称: BETA-MERCAPTOETHANOL, HSPC159, SULFATE ION
著者Zhou, D, Ge, H.H, Niu, L.W, Teng, M.K.
登録日2007-11-05
公開日2008-03-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the C-terminal conserved domain of human GRP, a galectin-related protein, reveals a function mode different from those of galectins.
Proteins, 71, 2008
8J5J
DownloadVisualize
BU of 8j5j by Molmil
The crystal structure of bat coronavirus RsYN04 RBD bound to the antibody S43
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, nano antibody S43
著者Zhao, R.C, Niu, S, Han, P, Qi, J.X, Gao, G.F, Wang, Q.H.
登録日2023-04-23
公開日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cross-species recognition of bat coronavirus RsYN04 and cross-reaction of SARS-CoV-2 antibodies against the virus.
Zool.Res., 44, 2023
3B4M
DownloadVisualize
BU of 3b4m by Molmil
Crystal Structure of Human PABPN1 RRM
分子名称: Polyadenylate-binding protein 2
著者Ge, H, Zhou, D, Teng, M, Niu, L.
登録日2007-10-24
公開日2008-01-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Crystal structure and possible dimerization of the single RRM of human PABPN1
Proteins, 71, 2008
3BS8
DownloadVisualize
BU of 3bs8 by Molmil
Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Glutamate-1-semialdehyde 2,1-aminomutase
著者Ge, H, Fan, J, Teng, M, Niu, L.
登録日2007-12-22
公開日2008-12-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Glutamate1-semialdehyde aminotransferase from Bacillus subtilis with bound pyridoxamine-5'-phosphate
Biochem.Biophys.Res.Commun., 402, 2010

222624

件を2024-07-17に公開中

PDB statisticsPDBj update infoContact PDBjnumon