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4NRO
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BU of 4nro by Molmil
Crystal structure of human ALKBH5 in complex with alpha-ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, RNA demethylase ALKBH5
著者Feng, C, Chen, Z, Liu, Y.
登録日2013-11-27
公開日2014-03-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4NRQ
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BU of 4nrq by Molmil
Crystal structure of human ALKBH5 in complex with pyridine-2,4-dicarboxylate
分子名称: MANGANESE (II) ION, PYRIDINE-2,4-DICARBOXYLIC ACID, RNA demethylase ALKBH5
著者Feng, C, Chen, Z, Liu, Y.
登録日2013-11-27
公開日2014-03-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4NRP
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BU of 4nrp by Molmil
Crystal structure of human ALKBH5 in complex with N-oxalylglycine
分子名称: MANGANESE (II) ION, N-OXALYLGLYCINE, RNA demethylase ALKBH5
著者Feng, C, Chen, Z, Liu, Y.
登録日2013-11-27
公開日2014-03-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4O7X
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BU of 4o7x by Molmil
Crystal structure of human ALKBH5 in complex with Mn2+
分子名称: MANGANESE (II) ION, RNA demethylase ALKBH5
著者Feng, C, Chen, Z, Liu, Y.
登録日2013-12-26
公開日2014-03-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4RIE
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BU of 4rie by Molmil
Landomycin Glycosyltransferase LanGT2
分子名称: Glycosyl transferase homolog
著者Tam, H.K, Gerhardt, S, Breit, B, Bechthold, A, Einsle, O.
登録日2014-10-06
公開日2015-01-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.162 Å)
主引用文献Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2.
Angew.Chem.Int.Ed.Engl., 54, 2015
4RIF
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BU of 4rif by Molmil
Landomycin Glycosyltransferase LanGT2, carbasugar substrate complex
分子名称: 2'-deoxy-5'-O-[(R)-{[(R)-{[(1S,3R,4R,5S)-3,4-dihydroxy-5-methylcyclohexyl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-3,4-dihydrothymidine, Glycosyl transferase homolog
著者Tam, H.K, Gerhardt, S, Breit, B, Bechthold, A, Einsle, O.
登録日2014-10-06
公開日2015-01-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2.
Angew.Chem.Int.Ed.Engl., 54, 2015
4RIG
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BU of 4rig by Molmil
Chimeric Glycosyltransferase LanGT2S8Ac
分子名称: Glycosyl transferase, MAGNESIUM ION
著者Tam, H.K, Gerhardt, S, Breit, B, Bechthold, A, Einsle, O.
登録日2014-10-06
公開日2015-01-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2.
Angew.Chem.Int.Ed.Engl., 54, 2015
4RIH
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BU of 4rih by Molmil
Chimeric Glycosyltransferase LanGT2S8Ac, carbasugar substrate complex
分子名称: 2'-deoxy-5'-O-[(R)-{[(R)-{[(1S,3R,4R,5S)-3,4-dihydroxy-5-methylcyclohexyl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-3,4-dihydrothymidine, Glycosyl transferase homolog,Glycosyl transferase, MAGNESIUM ION
著者Tam, H.K, Gerhardt, S, Breit, B, Bechthold, A, Einsle, O.
登録日2014-10-06
公開日2015-01-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2.
Angew.Chem.Int.Ed.Engl., 54, 2015
4RII
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BU of 4rii by Molmil
Chimeric Glycosyltransferase LanGT2S8Ac, TDP complex
分子名称: Glycosyl transferase homolog,Glycosyl transferase, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE
著者Tam, H.K, Gerhardt, S, Breit, B, Bechthold, A, Einsle, O.
登録日2014-10-06
公開日2015-01-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterization of O- and C-Glycosylating Variants of the Landomycin Glycosyltransferase LanGT2.
Angew.Chem.Int.Ed.Engl., 54, 2015
7BZ8
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BU of 7bz8 by Molmil
Template lasso peptide C24 mutant V3A
分子名称: lasso peptide
著者Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M.
登録日2020-04-27
公開日2021-04-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.
Chem Sci, 12, 2021
7BZ9
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BU of 7bz9 by Molmil
Template lasso peptide C24 mutant I4A
分子名称: lasso peptide
著者Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M.
登録日2020-04-27
公開日2021-04-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.
Chem Sci, 12, 2021
7BZ7
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BU of 7bz7 by Molmil
Template lasso peptide C24 mutant F15Y
分子名称: lasso peptide
著者Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M.
登録日2020-04-27
公開日2021-04-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.
Chem Sci, 12, 2021
7CU6
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BU of 7cu6 by Molmil
lasso peptide C24 mutant - A11V2C
分子名称: lasso peptide C24_A11V2C
著者Ma, M, Liu, X.H.
登録日2020-08-21
公開日2021-08-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.
Chem Sci, 12, 2021
7DXL
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BU of 7dxl by Molmil
Fragment-based Lead Discovery of Indazole-based Compounds as AXL Kinase Inhibitors
分子名称: 3-[4-[6-chloranyl-5-[[(3R)-pyrrolidin-3-yl]amino]-1H-indazol-3-yl]pyrazol-1-yl]benzenecarbonitrile, Tyrosine-protein kinase Mer
著者Anantharajan, J, Baburajendran, N.
登録日2021-01-19
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.146 Å)
主引用文献Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors.
Bioorg.Med.Chem., 49, 2021
7EP0
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BU of 7ep0 by Molmil
Crystal structure of ZYG11B bound to GSTE degron
分子名称: Protein zyg-11 homolog B, sodium 3,3'-(1E,1'E)-biphenyl-4,4'-diylbis(diazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate)
著者Yan, X, Li, Y.
登録日2021-04-26
公開日2021-07-14
最終更新日2021-09-01
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
7EP3
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BU of 7ep3 by Molmil
Crystal structure of ZER1 bound to GAGN degron
分子名称: Protein zer-1 homolog
著者Yan, X, Li, Y.
登録日2021-04-26
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.513 Å)
主引用文献Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
7EP2
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BU of 7ep2 by Molmil
Crystal structure of ZYG11B bound to GGFN degron
分子名称: Protein zyg-11 homolog B
著者Yan, X, Li, Y.
登録日2021-04-26
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
7EP5
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BU of 7ep5 by Molmil
Crystal structure of ZER1 bound to GKLH degron
分子名称: Protein zer-1 homolog
著者Yan, X, Li, Y.
登録日2021-04-26
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
7EP1
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BU of 7ep1 by Molmil
Crystal structure of ZYG11B bound to GFLH degron
分子名称: Protein zyg-11 homolog B
著者Yan, X, Li, Y.
登録日2021-04-26
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.852 Å)
主引用文献Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
7EP4
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BU of 7ep4 by Molmil
Crystal structure of ZER1 bound to GFLH degron
分子名称: Protein zer-1 homolog
著者Yan, X, Li, Y.
登録日2021-04-26
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
7C6C
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BU of 7c6c by Molmil
Crystal structure of native chitosanase from Bacillus subtilis MY002
分子名称: (2S)-2-hydroxybutanedioic acid, Chitosanase
著者Gou, Y, Liu, Z.C, Xie, T, Wang, G.G.
登録日2020-05-21
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.258 Å)
主引用文献Structure-based rational design of chitosanase CsnMY002 for high yields of chitobiose.
Colloids Surf B Biointerfaces, 202, 2021
7C6D
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BU of 7c6d by Molmil
Crystal structure of E19A mutant chitosanase from Bacillus subtilis MY002 complexed with 6 GlcN.
分子名称: 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, Chitosanase
著者Gou, Y, Liu, Z.C, Xie, T, Wang, G.G.
登録日2020-05-21
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structure-based rational design of chitosanase CsnMY002 for high yields of chitobiose.
Colloids Surf B Biointerfaces, 202, 2021
7D78
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BU of 7d78 by Molmil
The structure of thioesterase DcsB
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DltD domain-containing protein, ...
著者Tang, Y, Zhou, J.H, Wang, G.Q.
登録日2020-10-03
公開日2021-01-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.96543121 Å)
主引用文献A Polyketide Cyclase That Forms Medium-Ring Lactones.
J.Am.Chem.Soc., 143, 2021
7D79
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BU of 7d79 by Molmil
The structure of DcsB complex with its substrate analogue
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DltD domain-containing protein, ...
著者Tang, Y, Zhou, J.H, Wang, G.Q.
登録日2020-10-03
公開日2021-01-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.10411429 Å)
主引用文献A Polyketide Cyclase That Forms Medium-Ring Lactones.
J.Am.Chem.Soc., 143, 2021
6JLR
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BU of 6jlr by Molmil
Crystal structure of wild type MNK2 in complex with inhibitor
分子名称: 4-[5-(1-methylpyrazol-4-yl)pyridin-3-yl]benzamide, MAP kinase-interacting serine/threonine-protein kinase 2
著者Baburajendran, N, Hill, J.
登録日2019-03-06
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Stepwise Evolution of Fragment Hits against MAPK Interacting Kinases 1 and 2.
J.Med.Chem., 63, 2020

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