4MZF
| Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2a) peptide | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Peptide from Histone H3.2, ... | 著者 | Su, X, Ding, X, Li, H. | 登録日 | 2013-09-30 | 公開日 | 2014-03-26 | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | 主引用文献 | Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1 Genes Dev., 28, 2014
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4MZH
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8HSB
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8IQF
| Cryo-EM structure of the dimeric human CAF1-H3-H4 complex | 分子名称: | Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ... | 著者 | Liu, C.P, Yu, Z.Y, Xu, R.M. | 登録日 | 2023-03-16 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
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2FJP
| Human dipeptidyl peptidase IV/CD26 in complex with an inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM, ... | 著者 | Scapin, G, Patel, S.B, Becker, J.W. | 登録日 | 2006-01-03 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | (2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]- pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. J.Med.Chem., 49, 2006
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7DLX
| crystal structure of H2AM4>Z-H2B | 分子名称: | Histone H2B,Histone H2A | 著者 | Dai, L.C, Zhou, Z. | 登録日 | 2020-11-30 | 公開日 | 2021-06-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | 主引用文献 | Recognition of the inherently unstable H2A nucleosome by Swc2 is a major determinant for unidirectional H2A.Z exchange. Cell Rep, 35, 2021
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3HAB
| The structure of DPP4 in complex with piperidine fused benzimidazole 25 | 分子名称: | (2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scapin, G. | 登録日 | 2009-05-01 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitors Bioorg.Med.Chem.Lett., 19, 2009
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3HAC
| The structure of DPP-4 in complex with piperidine fused imidazopyridine 34 | 分子名称: | (7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scapin, G. | 登録日 | 2009-05-01 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitors Bioorg.Med.Chem.Lett., 19, 2009
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6ZOV
| ENTEROPEPTIDASE IN COMPLEX WITH COMPOUND 6 | 分子名称: | 1,2-ETHANEDIOL, 4-carbamimidamidobenzoic acid, Enteropeptidase, ... | 著者 | Cummings, M.D. | 登録日 | 2020-07-07 | 公開日 | 2020-10-21 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits. J.Pharmacol.Exp.Ther., 375, 2020
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4RGY
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6M6I
| Structure of HSV2 B-capsid portal vertex | 分子名称: | Coiled coils chain 1, Coiled coils chain 2, Major capsid protein, ... | 著者 | Wang, X.X, Wang, N. | 登録日 | 2020-03-14 | 公開日 | 2021-03-10 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation. Protein Cell, 11, 2020
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6M6H
| Structure of HSV2 C-capsid portal vertex | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Wang, X.X, Wang, N. | 登録日 | 2020-03-14 | 公開日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation. Protein Cell, 11, 2020
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6M6G
| Structure of HSV2 viron capsid portal vertex | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Coiled coils, ... | 著者 | Wang, X.X, Wang, N. | 登録日 | 2020-03-14 | 公開日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (5.39 Å) | 主引用文献 | Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation. Protein Cell, 11, 2020
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7RR3
| Structure of Deep-Sea Phage NrS-1 Primase-Polymerase N300 in complex with calcium and ddCTP | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, CALCIUM ION, Primase | 著者 | Wang, L, Yu, C, Sliz, P. | 登録日 | 2021-08-09 | 公開日 | 2022-01-12 | 最終更新日 | 2022-01-19 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Molecular Dissection of the Primase and Polymerase Activities of Deep-Sea Phage NrS-1 Primase-Polymerase. Front Microbiol, 12, 2021
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7RR4
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4MZG
| Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... | 著者 | Su, X, Ding, X, Li, H. | 登録日 | 2013-09-30 | 公開日 | 2014-03-26 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1 Genes Dev., 28, 2014
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6KN5
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8HN6
| Crystal structure of monoclonal antibody complexed with SARS-CoV-2 RBD | 分子名称: | Heavy chain of monoclonal antibody 3G10, Light chain of monoclonal antibody 3G10, Spike protein S1 | 著者 | Qi, J, Chen, Y. | 登録日 | 2022-12-07 | 公開日 | 2023-05-17 | 最終更新日 | 2023-06-07 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Characterization of RBD-specific cross-neutralizing antibodies responses against SARS-CoV-2 variants from COVID-19 convalescents. Front Immunol, 14, 2023
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8HN7
| Crystal structure of monoclonal antibody complexed with SARS-CoV-2 RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of monoclonal antibody 3C11, Light chain of monoclonal antibody 3C11, ... | 著者 | Qi, J, Chen, Y. | 登録日 | 2022-12-07 | 公開日 | 2023-05-17 | 最終更新日 | 2023-06-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Characterization of RBD-specific cross-neutralizing antibodies responses against SARS-CoV-2 variants from COVID-19 convalescents. Front Immunol, 14, 2023
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8YJY
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3T8M
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8WY4
| GajA tetramer with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-10-30 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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8X5N
| Tetramer Gabija with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, Gabija protein GajB, ... | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-11-17 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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8X5I
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8X51
| Cryo-EM structure of Gabija GajA in complex with DNA(focused refinement) | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*TP*T)-3'), ... | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-11-16 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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