4OSM
 
 | | Crystal structure of the S505H mutant of TAL effector dHax3 | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | | 著者 | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | 登録日 | 2014-02-13 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.454 Å) | | 主引用文献 | Revisiting the TALE repeat
Protein Cell, 5, 2014
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4OSJ
 | | Crystal structure of TAL effector reveals the recognition between asparagine and adenine | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | | 著者 | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | 登録日 | 2014-02-13 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Revisiting the TALE repeat
Protein Cell, 5, 2014
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4OTO
 | | Crystal structure of the S505W mutant of TAL effector dHax3 | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | | 著者 | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | 登録日 | 2014-02-14 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.588 Å) | | 主引用文献 | Revisiting the TALE repeat
Protein Cell, 5, 2014
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4OSZ
 | | Crystal structure of the S505P mutant of TAL effector dHax3 | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | | 著者 | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | 登録日 | 2014-02-13 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.614 Å) | | 主引用文献 | Revisiting the TALE repeat
Protein Cell, 5, 2014
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4OSR
 | | Crystal structure of the S505K mutant of TAL effector dHax3 | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*GP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | | 著者 | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | 登録日 | 2014-02-13 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.944 Å) | | 主引用文献 | Revisiting the TALE repeat
Protein Cell, 5, 2014
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7EEB
 | | Structure of the CatSpermasome | | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wu, J.P, Ke, M. | | 登録日 | 2021-03-18 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of a mammalian sperm cation channel complex.
Nature, 595, 2021
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8YT8
 | | Cryo-EM structure of the dystrophin glycoprotein complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-sarcoglycan, ... | | 著者 | Wu, J.P, Yan, Z, Wan, L. | | 登録日 | 2024-03-25 | | 公開日 | 2024-12-11 | | 最終更新日 | 2025-02-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure and assembly of the dystrophin glycoprotein complex.
Nature, 637, 2025
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7WJI
 | | Architecture of the human NALCN channelosome | | 分子名称: | Calmodulin-1, Protein unc-79 homolog, Protein unc-80 homolog, ... | | 著者 | Wu, J.P, Yan, Z, Zhou, L, Liu, H, Zhao, Q. | | 登録日 | 2022-01-06 | | 公開日 | 2022-04-20 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Architecture of the human NALCN channelosome.
Cell Discov, 8, 2022
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5XSY
 | | Structure of the Nav1.4-beta1 complex from electric eel | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein, Voltage-gated sodium channel beta subunit 1, ... | | 著者 | Yan, Z, Zhou, Q, Wu, J.P, Yan, N. | | 登録日 | 2017-06-15 | | 公開日 | 2017-08-09 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure of the Nav1.4-beta 1 Complex from Electric Eel.
Cell, 170, 2017
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9K6P
 | | Cryo-EM Structure of hAGO2D669A-siRNA-target (12-nt) | | 分子名称: | Protein argonaute-2, RNA (5'-R(P*GP*GP*CP*UP*CP*UP*UP*GP*U)-3'), RNA (5'-R(P*UP*AP*CP*AP*AP*GP*AP*GP*CP*C)-3') | | 著者 | Li, Z.Z, Xu, Q.K, Wu, J.P, Shen, E.Z. | | 登録日 | 2024-10-22 | | 公開日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanistic insights into RNA cleavage by human Argonaute2-siRNA complex.
Cell Res., 35, 2025
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9K6R
 | | Cryo-EM Structure of hAGO2D669A-siRNA-target (14-nt, uni-lobed) | | 分子名称: | MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*GP*AP*AP*AP*GP*GP*CP*UP*CP*UP*UP*GP*UP*U)-3'), ... | | 著者 | Li, Z.Z, Xu, Q.K, Wu, J.P, Shen, E.Z. | | 登録日 | 2024-10-22 | | 公開日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Mechanistic insights into RNA cleavage by human Argonaute2-siRNA complex.
Cell Res., 35, 2025
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9K6T
 | | Cryo-EM Structure of hAGO2D669A-siRNA-target (21-nt) | | 分子名称: | MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*AP*AP*CP*AP*AP*CP*AP*GP*AP*AP*AP*GP*GP*CP*UP*CP*UP*UP*GP*UP*U)-3'), ... | | 著者 | Li, Z.Z, Xu, Q.K, Wu, J.P, Shen, E.Z. | | 登録日 | 2024-10-22 | | 公開日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Mechanistic insights into RNA cleavage by human Argonaute2-siRNA complex.
Cell Res., 35, 2025
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9K6S
 | | Cryo-EM Structure of hAGO2D669A-siRNA-target (19-nt) | | 分子名称: | MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*CP*AP*AP*CP*AP*GP*AP*AP*AP*GP*GP*CP*UP*CP*UP*UP*GP*UP*U)-3'), ... | | 著者 | Li, Z.Z, Xu, Q.K, Wu, J.P, Shen, E.Z. | | 登録日 | 2024-10-22 | | 公開日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Mechanistic insights into RNA cleavage by human Argonaute2-siRNA complex.
Cell Res., 35, 2025
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9K6Q
 | | "Cryo-EM Structure of hAGO2D669A-siRNA-target (14-nt, sesqui-lobed) | | 分子名称: | MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*GP*AP*AP*AP*GP*GP*CP*UP*CP*UP*UP*GP*U)-3'), ... | | 著者 | Li, Z.Z, Xu, Q.K, Wu, J.P, Shen, E.Z. | | 登録日 | 2024-10-22 | | 公開日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Mechanistic insights into RNA cleavage by human Argonaute2-siRNA complex.
Cell Res., 35, 2025
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4XU5
 | | Crystal structure of MvINS bound to a bromine-derived 14C Diacylglycerol (DAG) at 2.1A resolution | | 分子名称: | (2S)-1-[(13-bromotridecanoyl)oxy]-3-hydroxypropan-2-yl tetradecanoate, DECANE, Uncharacterized protein, ... | | 著者 | Ren, R.B, Wu, J.P, Yan, C.Y, He, Y, Yan, N. | | 登録日 | 2015-01-25 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels
Science, 349, 2015
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4XU4
 | | Crystal structure of a mycobacterial Insig homolog MvINS from Mycobacterium vanbaalenii at 1.9A resolution | | 分子名称: | DECYLAMINE-N,N-DIMETHYL-N-OXIDE, Uncharacterized protein, nonyl beta-D-glucopyranoside | | 著者 | Ren, R.B, Wu, J.P, Yan, C.Y, He, Y, Yan, N. | | 登録日 | 2015-01-25 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels
Science, 349, 2015
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4XU6
 | | Crystal structure of cross-linked MvINS R77C trimer at 1.9A resolution | | 分子名称: | N-TRIDECANOIC ACID, Uncharacterized protein, octyl beta-D-glucopyranoside | | 著者 | Ren, R.B, Wu, J.P, Yan, C.Y, He, Y, Yan, N. | | 登録日 | 2015-01-25 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | | 主引用文献 | PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels
Science, 349, 2015
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8IYJ
 | | Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm | | 分子名称: | Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... | | 著者 | Zhou, L.N, Gui, M, Wu, J.P. | | 登録日 | 2023-04-05 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility.
Cell, 186, 2023
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4YHC
 | | Crystal structure of the WD40 domain of SCAP from fission yeast | | 分子名称: | CITRIC ACID, Sterol regulatory element-binding protein cleavage-activating protein | | 著者 | Gong, X, Li, J.X, Wu, J.P, Yan, C.Y, Yan, N. | | 登録日 | 2015-02-27 | | 公開日 | 2015-04-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition.
Cell Res., 25, 2015
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7YG6
 | | Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA | | 分子名称: | MAGNESIUM ION, Piwi, piRNA | | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | 登録日 | 2022-07-11 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YFX
 | | Cryo-EM structure of Hili in complex with piRNA | | 分子名称: | MAGNESIUM ION, Piwi-like protein 2, piRNA | | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | 登録日 | 2022-07-09 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YGN
 | | Cryo-EM structure of the Mili in complex with piRNA | | 分子名称: | MAGNESIUM ION, Piwi-like protein 2, piRNA | | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | 登録日 | 2022-07-11 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YFQ
 | | Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex | | 分子名称: | MAGNESIUM ION, Piwi, RNA (5'-R(*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | 登録日 | 2022-07-08 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YFY
 | | Cryo-EM structure of the Mili-piRNA- target ternary complex | | 分子名称: | MAGNESIUM ION, Piwi-like protein 2, RNA (5'-R(P*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | 登録日 | 2022-07-09 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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6A90
 | | Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana and Dc1a | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mu-diguetoxin-Dc1a, ... | | 著者 | Shen, H.Z, li, Z.Q, Jiang, Y, Pan, X.J, Wu, J.P, Cristofori-Armstrong, B, Smith, J.J, Chin, Y.K.Y, Lei, J.L, Zhou, Q, King, G.F, Yan, N. | | 登録日 | 2018-07-11 | | 公開日 | 2018-08-08 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
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