2FTM
 
 | | Crystal structure of trypsin complexed with the BPTI variant (Tyr35->Gly) | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | | 著者 | Hanson, W.M, Horvath, M.P, Goldenberg, D.P. | | 登録日 | 2006-01-24 | | 公開日 | 2006-02-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin.
J.Mol.Biol., 366, 2007
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2H16
 | | Structure of human ADP-ribosylation factor-like 5 (ARL5) | | 分子名称: | ADP-ribosylation factor-like protein 5A, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION | | 著者 | Rabeh, W.M, Tempel, W, Yaniw, D, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2006-05-16 | | 公開日 | 2006-06-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of human ADP-ribosylation factor-like 5 (ARL5)
To be Published
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3VEJ
 | | Crystal structure of the Get5 carboxyl domain from S. cerevisiae | | 分子名称: | PHOSPHATE ION, Ubiquitin-like protein MDY2 | | 著者 | Chartron, J.W, Vandervelde, D.G, Rao, M, Clemons Jr, W.M. | | 登録日 | 2012-01-08 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | | 主引用文献 | Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex.
J.Biol.Chem., 287, 2012
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7SQ0
 | | Get3 bound to ADP and the transmembrane domain of the tail-anchored protein Bos1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase ASNA1 homolog, MAGNESIUM ION, ... | | 著者 | Fry, M.Y, Maggiolo, A.O, Clemons Jr, W.M. | | 登録日 | 2021-11-04 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3.
Nat.Struct.Mol.Biol., 29, 2022
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7SPZ
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7SPY
 | | Get3 bound to ATP from G. intestinalis in the closed form | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATPase ASNA1 homolog, MAGNESIUM ION, ... | | 著者 | Fry, M.Y, Maggiolo, A.O, Clemons Jr, W.M. | | 登録日 | 2021-11-04 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3.
Nat.Struct.Mol.Biol., 29, 2022
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7UMB
 | | NanoBRET tracer Tram-bo bound to a KSR2-MEK1 complex | | 分子名称: | Dual specificity mitogen-activated protein kinase kinase 1, Kinase suppressor of Ras 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Marsiglia, W.M, Khan, K.M, Dar, A.C. | | 登録日 | 2022-04-06 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.231 Å) | | 主引用文献 | Live-cell target engagement of allosteric MEKi on MEK-RAF/KSR-14-3-3 complexes.
Nat.Chem.Biol., 20, 2024
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5NRA
 | | Crystal structure of human chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 7g | | 分子名称: | 1-(5-azanyl-4~{H}-1,2,4-triazol-3-yl)-~{N}-[2-(4-bromophenyl)ethyl]-~{N}-(2-methylpropyl)piperidin-4-amine, Chitotriosidase-1, GLYCEROL | | 著者 | Mazur, M, Olczak, J, Olejniczak, S, Koralewski, R, Czestkowski, W, Jedrzejczak, A, Golab, J, Dzwonek, K, Dymek, B, Sklepkiewicz, P, Zagozdzon, A, Noonan, T, Mahboubi, K, Conway, B, Sheeler, R, Beckett, P, Hungerford, W.M, Podjarny, A, Mitschler, A, Cousido-Siah, A, Fadel, F, Golebiowski, A. | | 登録日 | 2017-04-22 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.267 Å) | | 主引用文献 | Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.
J. Med. Chem., 61, 2018
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1FJG
 | | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN | | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V. | | 登録日 | 2000-08-08 | | 公開日 | 2000-09-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
Nature, 407, 2000
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1IBK
 | | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTIC PAROMOMYCIN | | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Ogle, J.M, Brodersen, D.E, Clemons Jr, W.M, Tarry, M.J, Carter, A.P, Ramakrishnan, V. | | 登録日 | 2001-03-28 | | 公開日 | 2001-05-04 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Recognition of cognate transfer RNA by the 30S ribosomal subunit.
Science, 292, 2001
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1IBM
 | | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH A MESSENGER RNA FRAGMENT AND COGNATE TRANSFER RNA ANTICODON STEM-LOOP BOUND AT THE A SITE | | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Ogle, J.M, Brodersen, D.E, Clemons Jr, W.M, Tarry, M.J, Carter, A.P, Ramakrishnan, V. | | 登録日 | 2001-03-28 | | 公開日 | 2001-05-04 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Recognition of cognate transfer RNA by the 30S ribosomal subunit.
Science, 292, 2001
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1IBL
 | | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH A MESSENGER RNA FRAGMENT AND COGNATE TRANSFER RNA ANTICODON STEM-LOOP BOUND AT THE A SITE AND WITH THE ANTIBIOTIC PAROMOMYCIN | | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Ogle, J.M, Brodersen, D.E, Clemons Jr, W.M, Tarry, M.J, Carter, A.P, Ramakrishnan, V. | | 登録日 | 2001-03-28 | | 公開日 | 2001-05-04 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Recognition of cognate transfer RNA by the 30S ribosomal subunit.
Science, 292, 2001
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6XNT
 | | Crystal structure of I91A mutant of human CEACAM1 | | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, octyl beta-D-glucopyranoside | | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | | 登録日 | 2020-07-04 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium.
Commun Biol, 4, 2021
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6XNW
 | | Crystal structure of V39A mutant of human CEACAM1 | | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, NICKEL (II) ION | | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | | 登録日 | 2020-07-04 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium.
Commun Biol, 4, 2021
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6XO1
 | | Crystal structure of N97A mutant of human CEACAM1 | | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID | | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | | 登録日 | 2020-07-05 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.758 Å) | | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium.
Commun Biol, 4, 2021
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6XNO
 | | Crystal structure of E99A mutant of human CEACAM1 | | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside | | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | | 登録日 | 2020-07-03 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium.
Commun Biol, 4, 2021
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3UG7
 | | Crystal Structure of Get3 from Methanocaldococcus jannaschii | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | | 著者 | Suloway, C.J.M, Rome, M.E, Clemons Jr, W.M. | | 登録日 | 2011-11-02 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | | 主引用文献 | Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue.
Embo J., 31, 2012
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3UG6
 | | Crystal Structure of Get3 from Methanocaldococcus jannaschii | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | | 著者 | Suloway, C.J.M, Rome, M.E, Clemons Jr, W.M. | | 登録日 | 2011-11-02 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue.
Embo J., 31, 2012
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3SZ7
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1J5E
 | | Structure of the Thermus thermophilus 30S Ribosomal Subunit | | 分子名称: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Wimberly, B.T, Brodersen, D.E, Clemons Jr, W.M, Morgan-Warren, R, Carter, A.P, Vonrhein, C, Hartsch, T, Ramakrishnan, V. | | 登録日 | 2002-04-08 | | 公開日 | 2002-04-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structure of the 30S ribosomal subunit.
Nature, 407, 2000
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1WP5
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8K1Y
 | | Crystal structure of human serum albumin and ruthenium Val complex adduct | | 分子名称: | Albumin, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Gong, W.J, Xie, L.L, Wang, W.M, Wang, H.F. | | 登録日 | 2023-07-11 | | 公開日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of human serum albumin and ruthenium VaL complex adduct
To Be Published
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1XRK
 | | Crystal structure of a mutant bleomycin binding protein from Streptoalloteichus hindustanus displaying increased thermostability | | 分子名称: | BLEOMYCIN A2, Bleomycin resistance protein, SULFATE ION | | 著者 | Brouns, S.J.J, Wu, H, Akerboom, J, Turnbull, A.P, de Vos, W.M, Van der Oost, J. | | 登録日 | 2004-10-15 | | 公開日 | 2005-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Engineering a selectable marker for hyperthermophiles
J.Biol.Chem., 280, 2005
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1XOG
 | | N9 Tern Influenza neuraminidase complexed with a 2,5-Disubstituted tetrahydrofuran-5-carboxylic acid | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-2,5-ANHYDRO-3,4-DIDEOXY-4-(METHOXYCARBONYL)PENTONIC ACID, Neuraminidase, ... | | 著者 | Wang, G.T, Wang, S, Gentles, R, Sowin, T, Maring, C.J, Kempf, D.J, Kati, W.M, Stoll, V, Stewart, K.D, Laver, G. | | 登録日 | 2004-10-06 | | 公開日 | 2005-01-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core.
Bioorg.Med.Chem.Lett., 15, 2005
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1XS8
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