8JPW
 
 | | Crystal Structure of Single-chain L-Glutamate Oxidase Mutant from Streptomyces sp. X-119-6 | | 分子名称: | 2-OXOGLUTARIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, L-glutamate oxidase, ... | | 著者 | Yamaguchi, H, Takahashi, K, Tatsumi, M, Tagami, U, Mizukoshi, T, Miyano, H, Sugiki, M. | | 登録日 | 2023-06-13 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Development of a novel single-chain l-glutamate oxidase from Streptomyces sp. X-119-6 by inserting flexible linkers.
Enzyme.Microb.Technol., 170, 2023
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1IPK
 | | CRYSTAL STRUCTURES OF RECOMBINANT AND NATIVE SOYBEAN BETA-CONGLYCININ BETA HOMOTRIMERS | | 分子名称: | BETA-CONGLYCININ, BETA CHAIN | | 著者 | Maruyama, N, Adachi, M, Takahashi, K, Yagasaki, K, Kohno, M, Takenaka, Y, Okuda, E, Nakagawa, S, Mikami, B, Utsumi, S. | | 登録日 | 2001-05-16 | | 公開日 | 2002-05-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structures of recombinant and native soybean beta-conglycinin beta homotrimers.
Eur.J.Biochem., 268, 2001
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1A0F
 | | CRYSTAL STRUCTURE OF GLUTATHIONE S-TRANSFERASE FROM ESCHERICHIA COLI COMPLEXED WITH GLUTATHIONESULFONIC ACID | | 分子名称: | GLUTATHIONE S-TRANSFERASE, GLUTATHIONE SULFONIC ACID | | 著者 | Nishida, M, Harada, S, Noguchi, S, Inoue, H, Takahashi, K, Satow, Y. | | 登録日 | 1997-11-29 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Three-dimensional structure of Escherichia coli glutathione S-transferase complexed with glutathione sulfonate: catalytic roles of Cys10 and His106.
J.Mol.Biol., 281, 1998
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7WAB
 | | Crystal structure of the prolyl endoprotease, PEP, from Aspergillus niger | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPASS (Complex proteins associated with Set1p) component shg1 family protein, ... | | 著者 | Miyazono, K, Kubota, K, Takahashi, K, Tanokura, M. | | 登録日 | 2021-12-14 | | 公開日 | 2022-01-12 | | 最終更新日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure and substrate recognition mechanism of the prolyl endoprotease PEP from Aspergillus niger.
Biochem.Biophys.Res.Commun., 591, 2022
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5ZBD
 | | Crystal structure of tryptophan oxidase (C395A mutant) from Chromobacterium violaceum | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent L-tryptophan oxidase VioA, TRYPTOPHAN | | 著者 | Yamaguchi, H, Tatsumi, M, Takahashi, K, Tagami, U, Sugiki, M, Kashiwagi, T, Okazaki, S, Mizukoshi, T, Asano, Y. | | 登録日 | 2018-02-11 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Protein engineering for improving the thermostability of tryptophan oxidase and insights from structural analysis.
J. Biochem., 164, 2018
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5ZBC
 | | Crystal structure of Se-Met tryptophan oxidase (C395A mutant) from Chromobacterium violaceum | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent L-tryptophan oxidase VioA | | 著者 | Yamaguchi, H, Tatsumi, M, Takahashi, K, Tagami, U, Sugiki, M, Kashiwagi, T, Okazaki, S, Mizukoshi, T, Asano, Y. | | 登録日 | 2018-02-11 | | 公開日 | 2018-12-19 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Protein engineering for improving the thermostability of tryptophan oxidase and insights from structural analysis.
J. Biochem., 164, 2018
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2D18
 | | Solution RNA structure of loop region of the HIV-1 dimerization initiation site in the extended-duplex dimer | | 分子名称: | 5'-R(*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*GP*GP*C)-3' | | 著者 | Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G. | | 登録日 | 2005-08-15 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
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2D1B
 | | Solution RNA structure model of the HIV-1 dimerization initiation site in the kissing-loop dimer | | 分子名称: | RNA | | 著者 | Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G. | | 登録日 | 2005-08-15 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
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7VUU
 | | Crystal structure of AlleyCat10 with inhibitor | | 分子名称: | 5-nitro-1H-benzotriazole, AlleyCat, CALCIUM ION | | 著者 | Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K. | | 登録日 | 2021-11-04 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | NMR-guided directed evolution.
Nature, 610, 2022
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7VUT
 | | Crystal structure of AlleyCat10 | | 分子名称: | AlleyCat10, CALCIUM ION | | 著者 | Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K. | | 登録日 | 2021-11-04 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | NMR-guided directed evolution.
Nature, 610, 2022
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7VUS
 | | Crystal structure of AlleyCat9 with 5-nitro-benzotriazole | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-nitro-1H-benzotriazole, AlleyCat, ... | | 著者 | Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K. | | 登録日 | 2021-11-04 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | NMR-guided directed evolution.
Nature, 610, 2022
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7VUR
 | | Crystal structure of AlleyCat9 with calcium but no inhibitor | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, AlleyCat, CALCIUM ION | | 著者 | Margheritis, E, Takahashi, K, Korendovych, I.V, Tame, J.R.H. | | 登録日 | 2021-11-04 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | NMR-guided directed evolution.
Nature, 610, 2022
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2D19
 | | Solution RNA structure of loop region of the HIV-1 dimerization initiation site in the kissing-loop dimer | | 分子名称: | 5'-R(*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*GP*GP*C)-3' | | 著者 | Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G. | | 登録日 | 2005-08-15 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
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2D17
 | | Solution RNA structure of stem-bulge-stem region of the HIV-1 dimerization initiation site | | 分子名称: | 5'-R(*CP*GP*GP*CP*AP*AP*GP*AP*GP*GP*CP*GP*AP*CP*CP*C)-3', 5'-R(*GP*GP*GP*UP*CP*GP*GP*CP*UP*UP*GP*CP*UP*G)-3' | | 著者 | Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G. | | 登録日 | 2005-08-15 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
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2D1A
 | | Solution RNA structure model of the HIV-1 dimerization initiation site in the extended-duplex dimer | | 分子名称: | RNA | | 著者 | Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G. | | 登録日 | 2005-08-15 | | 公開日 | 2005-11-01 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
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8P2U
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8WGS
 | | Crystal structure of V30M-TTR in complex with compound 4 | | 分子名称: | Transthyretin, [3,5-bis(iodanyl)-4-oxidanyl-phenyl]-(2-ethyl-4-iodanyl-1-benzofuran-3-yl)methanone | | 著者 | Yokoyama, T. | | 登録日 | 2023-09-22 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.
J.Med.Chem., 67, 2024
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8WGT
 | | Crystal structure of V30M-TTR in complex with compound 7 | | 分子名称: | Transthyretin, [4,7-bis(chloranyl)-2-ethyl-1-benzofuran-3-yl]-[3,5-bis(iodanyl)-4-oxidanyl-phenyl]methanone | | 著者 | Yokoyama, T. | | 登録日 | 2023-09-22 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | | 主引用文献 | Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.
J.Med.Chem., 67, 2024
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8WGU
 | | Crystal structure of V30M-TTR in complex with compound 20 | | 分子名称: | Transthyretin, [3,5-bis(iodanyl)-4-oxidanyl-phenyl]-[2-ethyl-4,7-bis(fluoranyl)-1-benzofuran-3-yl]methanone | | 著者 | Yokoyama, T. | | 登録日 | 2023-09-22 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.508 Å) | | 主引用文献 | Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.
J.Med.Chem., 67, 2024
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6LF2
 | | SeviL bound to asialo-GM1 saccharide | | 分子名称: | SeviL, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Kamata, K, Ozeki, Y, Park, S.-Y, Tame, J.R.H. | | 登録日 | 2019-11-28 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The structure of SeviL, a GM1b/asialo-GM1 binding R-type lectin from the mussel Mytilisepta virgata.
Sci Rep, 10, 2020
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6LF1
 | | SeviL, a GM1b/asialo-GM1 binding lectin | | 分子名称: | CHLORIDE ION, SeviL | | 著者 | Kamata, K, Ozeki, Y, Park, S.-Y, Tame, J.R.H. | | 登録日 | 2019-11-28 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The structure of SeviL, a GM1b/asialo-GM1 binding R-type lectin from the mussel Mytilisepta virgata.
Sci Rep, 10, 2020
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3SYU
 | | Re-refined coordinates for pdb entry 1det - ribonuclease T1 carboxymethylated at GLU 58 in complex with 2'GMP | | 分子名称: | GUANOSINE-2'-MONOPHOSPHATE, Guanyl-specific ribonuclease T1, SODIUM ION, ... | | 著者 | Smart, O.S, Womack, T.O, Bricogne, G. | | 登録日 | 2011-07-18 | | 公開日 | 2012-03-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER.
Acta Crystallogr.,Sect.D, 68, 2012
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8HU6
 | | AMP deaminase 2 in complex with AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, AMP deaminase 2, SULFATE ION, ... | | 著者 | Adachi, T, Doi, S. | | 登録日 | 2022-12-22 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | The discovery of 3,3-dimethyl-1,2,3,4-tetrahydroquinoxaline-1-carboxamides as AMPD2 inhibitors with a novel mechanism of action.
Bioorg.Med.Chem.Lett., 80, 2023
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8HUB
 | | AMP deaminase 2 in complex with an inhibitor | | 分子名称: | 3,3-dimethyl-4-(phenylmethyl)-2~{H}-quinoxaline-1-carboxamide, AMP deaminase 2, ZINC ION | | 著者 | Adachi, T, Doi, S. | | 登録日 | 2022-12-23 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | The discovery of 3,3-dimethyl-1,2,3,4-tetrahydroquinoxaline-1-carboxamides as AMPD2 inhibitors with a novel mechanism of action.
Bioorg.Med.Chem.Lett., 80, 2023
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1BI6
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