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6RU0
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BU of 6ru0 by Molmil
Light-Regulation of Imidazole Glycerol Phosphate Synthase by Interference with its Allosteric Machinery through Photo-Sensitive Unnatural Amino Acids
分子名称: Imidazole glycerol phosphate synthase subunit HisF, Imidazole glycerol phosphate synthase subunit HisH, PHOSPHATE ION
著者Kneuttinger, A, Rajendran, C, Sterner, R.
登録日2019-05-27
公開日2020-05-20
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.648 Å)
主引用文献Light Regulation of Enzyme Allostery through Photo-responsive Unnatural Amino Acids.
Cell Chem Biol, 26, 2019
4EVZ
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BU of 4evz by Molmil
Structure of HisF-LUCA
分子名称: HYDROGENPHOSPHATE ION, HisF-LUCA
著者Reisinger, B, Sperl, J, Rajendran, C, Merkl, R, Sterner, R.
登録日2012-04-26
公開日2013-11-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.462 Å)
主引用文献Evidence for the existence of elaborate enzyme complexes in the Paleoarchean era.
J.Am.Chem.Soc., 136, 2014
2GVQ
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BU of 2gvq by Molmil
Anthranilate phosphoribosyl-transferase (TRPD) from S. solfataricus in complex with anthranilate
分子名称: 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase
著者Marino, M, Deuss, M, Sterner, R, Mayans, O.
登録日2006-05-03
公開日2006-05-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus.
J.Biol.Chem., 281, 2006
3GBR
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BU of 3gbr by Molmil
Anthranilate phosphoribosyl-transferase (TRPD) double mutant D83G F149S from S. solfataricus
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, DI(HYDROXYETHYL)ETHER, ...
著者Bruning, M, Schlee, S, Deuss, M, Ivens, A, Mayans, O, Sterner, R.
登録日2009-02-20
公開日2009-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release
Biochemistry, 48, 2009
4MM1
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BU of 4mm1 by Molmil
GGGPS from Methanothermobacter thermautotrophicus
分子名称: Geranylgeranylglyceryl phosphate synthase, SN-GLYCEROL-1-PHOSPHATE, TRIETHYLENE GLYCOL
著者Rajendran, C, Peterhoff, D, Beer, B, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P.
登録日2013-09-07
公開日2014-06-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8004 Å)
主引用文献A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization.
Mol.Microbiol., 92, 2014
4NAE
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BU of 4nae by Molmil
PcrB from Geobacillus kaustophilus, with bound G1P
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Heptaprenylglyceryl phosphate synthase, SN-GLYCEROL-1-PHOSPHATE
著者Peterhoff, D, Beer, B, Rajendran, C, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P.
登録日2013-10-22
公開日2014-06-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization.
Mol.Microbiol., 92, 2014
6RG0
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BU of 6rg0 by Molmil
Structure of pdxj
分子名称: Pyridoxine 5'-phosphate synthase
著者Rohweder, B, Rajendran, C, Sterner, R.
登録日2019-04-16
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.074 Å)
主引用文献Library Selection with a Randomized Repertoire of ( beta alpha )8-Barrel Enzymes Results in Unexpected Induction of Gene Expression.
Biochemistry, 58, 2019
4NAF
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BU of 4naf by Molmil
PrcB from Geobacillus kaustophilus, apo structure
分子名称: Heptaprenylglyceryl phosphate synthase
著者Peterhoff, D, Beer, B, Rajendran, C, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P.
登録日2013-10-22
公開日2014-06-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization.
Mol.Microbiol., 92, 2014
4EWN
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BU of 4ewn by Molmil
Structure of HisF-D130V+D176V with bound rCdRP
分子名称: 1-(O-carboxy-phenylamino)-1-deoxy-D-ribulose-5-phosphate, Imidazole glycerol phosphate synthase subunit HisF
著者Reisinger, B, Bocola, M, Rajendran, C, List, F, Sterner, R.
登録日2012-04-27
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献A sugar isomerization reaction established on various (beta-alpha)8-barrel scaffolds is based on substrate-assisted catalysis
Protein Eng.Des.Sel., 25, 2012
1ZYK
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BU of 1zyk by Molmil
Anthranilate Phosphoribosyltransferase in complex with PRPP, anthranilate and magnesium
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase, ...
著者Marino, M, Deuss, M, Sterner, R, Mayans, O.
登録日2005-06-10
公開日2006-05-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus.
J.Biol.Chem., 281, 2006
1ZXY
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BU of 1zxy by Molmil
Anthranilate Phosphoribosyltransferase from Sulfolobus solfataricus in complex with PRPP and Magnesium
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION
著者Marino, M, Deuss, M, Sterner, R, Mayans, O.
登録日2005-06-09
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus.
J.Biol.Chem., 281, 2006
2C3Z
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BU of 2c3z by Molmil
Crystal structure of a truncated variant of indole-3-glycerol phosphate synthase from Sulfolobus solfataricus
分子名称: INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE, SULFATE ION
著者Schneider, A, Knoechel, T, Darimont, B, Hennig, M, Dietrich, S, Kirschner, K, Sterner, R.
登録日2005-10-13
公開日2005-10-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Role of the N-Terminal Extension of the (Betaalpha)(8)-Barrel Enzyme Indole-3-Glycerol Phosphate Synthase for its Fold, Stability, and Catalytic Activity.
Biochemistry, 44, 2005
5NF1
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BU of 5nf1 by Molmil
crystal structure of variants
分子名称: Geranylgeranylglyceryl phosphate synthase
著者Linde, M, Rajendran, C, Babinger, P, Sterner, R.
登録日2017-03-13
公開日2018-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献crystal structure of variants
To Be Published
1ROF
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BU of 1rof by Molmil
NMR STUDY OF 4FE-4S FERREDOXIN OF THERMATOGA MARITIMA
分子名称: FERREDOXIN, IRON/SULFUR CLUSTER
著者Roesch, P, Sticht, H, Wildegger, G, Bentrop, D, Darimont, B, Sterner, R.
登録日1995-11-24
公開日1996-06-10
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献An NMR-derived model for the solution structure of oxidized Thermotoga maritima 1[Fe4-S4] ferredoxin.
Eur.J.Biochem., 237, 1996
4JEJ
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BU of 4jej by Molmil
GGGPS from Flavobacterium johnsoniae
分子名称: Geranylgeranylglyceryl phosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Peterhoff, D, Beer, B, Rajendran, C, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P.
登録日2013-02-27
公開日2014-06-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization.
Mol.Microbiol., 92, 2014
4J5N
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BU of 4j5n by Molmil
Crystal Structure of a Deinococcus radiodurans PTE-like lactonase (drPLL) mutant Y28L/D71N/E101G/E179D/V235L/L270M
分子名称: COBALT (II) ION, Phosphotriesterase, putative
著者Meier, M.M, Rajendran, C, Malisi, C, Fox, N.G, Xu, C, Schlee, S, Barondeau, D.P, Hocker, B, Sterner, R, Raushel, F.M.
登録日2013-02-08
公開日2013-07-24
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template.
J.Am.Chem.Soc., 135, 2013
1THF
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BU of 1thf by Molmil
CYCLASE SUBUNIT OF IMIDAZOLEGLYCEROLPHOSPHATE SYNTHASE FROM THERMOTOGA MARITIMA
分子名称: HISF PROTEIN, PHOSPHATE ION
著者Lang, D.A, Wilmanns, M.
登録日1998-09-17
公開日2000-07-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural evidence for evolution of the beta/alpha barrel scaffold by gene duplication and fusion.
Science, 289, 2000
1NSJ
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BU of 1nsj by Molmil
CRYSTAL STRUCTURE OF PHOSPHORIBOSYL ANTHRANILATE ISOMERASE FROM THERMOTOGA MARITIMA
分子名称: PHOSPHATE ION, PHOSPHORIBOSYL ANTHRANILATE ISOMERASE
著者Hennig, M, Jansonius, J.N.J.
登録日1996-09-13
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure at 2.0 A resolution of phosphoribosyl anthranilate isomerase from the hyperthermophile Thermotoga maritima: possible determinants of protein stability.
Biochemistry, 36, 1997
7AC8
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BU of 7ac8 by Molmil
Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex.
分子名称: GLUTAMINE, Imidazole glycerol phosphate synthase subunit HisF, Imidazole glycerol phosphate synthase subunit HisH, ...
著者Sung, S, Wilmanns, M.
登録日2020-09-10
公開日2021-05-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Molecular basis for the allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex.
Nat Commun, 12, 2021
6HTE
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BU of 6hte by Molmil
Sulfolobus solfataricus Tryptophan Synthase B2a
分子名称: DI(HYDROXYETHYL)ETHER, PYRIDOXAL-5'-PHOSPHATE, Tryptophan synthase beta chain 2
著者Fleming, J, Mayans, O, Bucher, R.
登録日2018-10-04
公開日2018-11-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.961 Å)
主引用文献Evolutionary Morphing of Tryptophan Synthase: Functional Mechanisms for the Enzymatic Channeling of Indole.
J.Mol.Biol., 430, 2018
8BKD
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BU of 8bkd by Molmil
structure of RutB
分子名称: N-(AMINOCARBONYL)-BETA-ALANINE, Ureidoacrylate amidohydrolase RutB
著者Rajendran, C.
登録日2022-11-09
公開日2023-01-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and Functional Characterization of the Ureidoacrylate Amidohydrolase RutB from Escherichia coli .
Biochemistry, 62, 2023
8BLM
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Structure of RutB
分子名称: Ureidoacrylate amidohydrolase RutB
著者Rajendran, C.
登録日2022-11-09
公開日2023-01-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Characterization of the Ureidoacrylate Amidohydrolase RutB from Escherichia coli .
Biochemistry, 62, 2023
8BLL
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Structure of RutB
分子名称: ACETATE ION, Ureidoacrylate amidohydrolase RutB
著者Rajendran, C.
登録日2022-11-09
公開日2023-01-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural and Functional Characterization of the Ureidoacrylate Amidohydrolase RutB from Escherichia coli .
Biochemistry, 62, 2023
5EY5
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BU of 5ey5 by Molmil
LBCATS
分子名称: LBCA-b, LBCATS-a, PYRIDOXAL-5'-PHOSPHATE, ...
著者Busch, F, Rajendran, C, Schlee, S, Heyn, K, Merkl, R, Sterner, R.
登録日2015-11-24
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.972 Å)
主引用文献LBCATS
To Be Published
8BLN
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Structure of RutB
分子名称: Ureidoacrylate amidohydrolase RutB
著者Rajendran, C.
登録日2022-11-09
公開日2023-09-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural and Functional Characterization of the Ureidoacrylate Amidohydrolase RutB from Escherichia coli .
Biochemistry, 62, 2023

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