7N1J
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7N1K
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7N3T
| TrkA ECD complex with designed miniprotein ligand | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Jude, K.M, Cao, L, Garcia, K.C. | 登録日 | 2021-06-01 | 公開日 | 2022-04-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Design of protein-binding proteins from the target structure alone. Nature, 605, 2022
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5EIL
| Computational design of a high-affinity metalloprotein homotrimer containing a metal chelating non-canonical amino acid | 分子名称: | FE (III) ION, TRI-05 | 著者 | Sankaran, B, Zwart, P.H, Mills, J.H, Pereira, J.H, Baker, D. | 登録日 | 2015-10-30 | 公開日 | 2016-11-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Computational design of a homotrimeric metalloprotein with a trisbipyridyl core. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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8SZZ
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8SK7
| Cryo-EM structure of designed Influenza HA binder, HA_20, bound to Influenza HA (Strain: Iowa43) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA_20 minibinder (RFdiffusion-designed), ... | 著者 | Borst, A.J, Bennett, N.R. | 登録日 | 2023-04-18 | 公開日 | 2023-06-14 | 最終更新日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | De novo design of protein structure and function with RFdiffusion. Nature, 620, 2023
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6E9T
| DHF58 filament | 分子名称: | DHF58 filament | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | 登録日 | 2018-08-01 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | De novo design of self-assembling helical protein filaments. Science, 362, 2018
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6E9Y
| DHF38 filament | 分子名称: | DHF38 filament | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | 登録日 | 2018-08-01 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | De novo design of self-assembling helical protein filaments. Science, 362, 2018
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6E9X
| DHF91 filament | 分子名称: | DHF91 filament | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | 登録日 | 2018-08-01 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | De novo design of self-assembling helical protein filaments. Science, 362, 2018
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8FAR
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6XT4
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6XSS
| CryoEM structure of designed helical fusion protein C4_nat_HFuse-7900 | 分子名称: | C4_nat_HFuse-7900 | 著者 | Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. | 登録日 | 2020-07-16 | 公開日 | 2020-12-23 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Design of multi-scale protein complexes by hierarchical building block fusion. Nat Commun, 12, 2021
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6XI6
| Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks | 分子名称: | helical fusion design | 著者 | Bera, A.K, Hsia, Y, Kang, A.S, Shankaran, B, Baker, D. | 登録日 | 2020-06-19 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Design of multi-scale protein complexes by hierarchical building block fusion. Nat Commun, 12, 2021
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6XH5
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6B85
| Crystal structure of transmembrane protein TMHC4_R | 分子名称: | TMHC4_R | 著者 | Lu, P, DiMaio, F, Min, D, Bowie, J, Wei, K.Y, Baker, D. | 登録日 | 2017-10-05 | 公開日 | 2018-03-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.889 Å) | 主引用文献 | Accurate computational design of multipass transmembrane proteins. Science, 359, 2018
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6B87
| Crystal structure of transmembrane protein TMHC2_E | 分子名称: | TMHC2_E | 著者 | Lu, P, DiMaio, F, Min, D, Wei, K.Y, Bowie, J, Baker, D. | 登録日 | 2017-10-05 | 公開日 | 2018-03-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.947 Å) | 主引用文献 | Accurate computational design of multipass transmembrane proteins. Science, 359, 2018
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5K7V
| Computational Design of Self-Assembling Cyclic Protein Homooligomers | 分子名称: | Designed protein HR00C3 | 著者 | Sankaran, B, Zwart, P.H, Fallas, J.A, Pereira, J.H, Ueda, G, Baker, D. | 登録日 | 2016-05-26 | 公開日 | 2017-04-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.165 Å) | 主引用文献 | Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem, 9, 2017
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5KBA
| Computational Design of Self-Assembling Cyclic Protein Homooligomers | 分子名称: | Designed protein ANK1C2 | 著者 | Sankaran, B, Zwart, P.H, Fallas, J.A, Pereira, J.H, Ueda, G, Baker, D. | 登録日 | 2016-06-02 | 公開日 | 2017-04-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem, 9, 2017
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8CUX
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8CUV
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8CUU
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8CUT
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8CUS
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8CWZ
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8CWS
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