6CJE
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![BU of 6cje by Molmil](/molmil-images/mine/6cje) | Crystal Structure of Mnk2-D228G in complex with Inhibitor | 分子名称: | 4-[(9H-purin-6-yl)amino]benzamide, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION | 著者 | Han, Q. | 登録日 | 2018-02-26 | 公開日 | 2018-05-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
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6CJY
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![BU of 6cjy by Molmil](/molmil-images/mine/6cjy) | Crystal Structure of Mnk2-D228G in complex with Inhibitor | 分子名称: | 5-[(7H-purin-6-yl)amino]-1H-isoindol-1-one, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION | 著者 | Han, Q. | 登録日 | 2018-02-27 | 公開日 | 2018-05-09 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
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6CK3
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![BU of 6ck3 by Molmil](/molmil-images/mine/6ck3) | Co-crytsal Structure of MNK2 in Complex With an Inhibitor | 分子名称: | (3R)-3-methyl-5-[(pyrimidin-4-yl)amino]-2,3-dihydro-1H-isoindol-1-one, CHLORIDE ION, MAP kinase-interacting serine/threonine-protein kinase 2, ... | 著者 | Han, Q. | 登録日 | 2018-02-27 | 公開日 | 2018-05-09 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
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6CJW
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![BU of 6cjw by Molmil](/molmil-images/mine/6cjw) | Crystal Structure of Mnk2-D228G in Complex With Inhibitor | 分子名称: | 3-(pyridin-4-yl)imidazo[1,2-b]pyridazine, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION | 著者 | Han, Q. | 登録日 | 2018-02-27 | 公開日 | 2018-05-09 | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | 主引用文献 | Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. J. Med. Chem., 61, 2018
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6ECK
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![BU of 6eck by Molmil](/molmil-images/mine/6eck) | Pyruvate Kinase Isoform L-type with phosphorylated Ser113 (pS113) in complex with FBP | 分子名称: | 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, CITRATE ANION, ... | 著者 | Padyana, A, Tong, S. | 登録日 | 2018-08-08 | 公開日 | 2019-12-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production. Cell Rep, 29, 2019
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6ECH
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![BU of 6ech by Molmil](/molmil-images/mine/6ech) | Pyruvate Kinase Isoform L-type with phosphorylated Ser12 (pS12) in complex with FBP | 分子名称: | 1,2-ETHANEDIOL, 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Padyana, A, Tong, S. | 登録日 | 2018-08-07 | 公開日 | 2019-12-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production. Cell Rep, 29, 2019
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