8S0S
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![BU of 8s0s by Molmil](/molmil-images/mine/8s0s) | A fragment-based inhibitor of SHP2 | 分子名称: | (1R,5S)-8-[7-(4-chloranyl-2-methyl-indazol-5-yl)-5H-pyrrolo[2,3-b]pyrazin-3-yl]-8-azabicyclo[3.2.1]octan-3-amine, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Cleasby, A, Price, A. | 登録日 | 2024-02-14 | 公開日 | 2024-03-20 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2). J.Med.Chem., 67, 2024
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6L8S
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![BU of 6l8s by Molmil](/molmil-images/mine/6l8s) | High resolution crystal structure of crustacean hemocyanin. | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Masuda, T, Mikami, B, Baba, S. | 登録日 | 2019-11-07 | 公開日 | 2020-05-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | The high-resolution crystal structure of lobster hemocyanin shows its enzymatic capability as a phenoloxidase. Arch.Biochem.Biophys., 688, 2020
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6KOS
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![BU of 6kos by Molmil](/molmil-images/mine/6kos) | |
5ZC6
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![BU of 5zc6 by Molmil](/molmil-images/mine/5zc6) | Solution structure of H-RasT35S mutant protein in complex with KBFM123 | 分子名称: | 3-oxidanyl-~{N}-[[(2~{R})-oxolan-2-yl]methyl]naphthalene-2-carboxamide, GTPase HRas, MAGNESIUM ION, ... | 著者 | Matsumoto, S, Hayashi, Y, Hiraga, T, Matsuo, K, Kataoka, T. | 登録日 | 2018-02-15 | 公開日 | 2018-09-12 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Basis for Allosteric Inhibition of GTP-Bound H-Ras Protein by a Small-Molecule Compound Carrying a Naphthalene Ring Biochemistry, 57, 2018
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5Z98
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![BU of 5z98 by Molmil](/molmil-images/mine/5z98) | Crystal Structure of the Primate APOBEC3H Dimer mediated by RNA Duplex | 分子名称: | Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like protein 3H, RNA (5'-R(*AP*UP*AP*CP*CP*CP*GP*GP*CP*A)-3'), RNA (5'-R(P*CP*UP*GP*CP*CP*GP*GP*GP*UP*A)-3'), ... | 著者 | Matsuoka, T, Nagae, T, Ode, H, Watanabe, N, Iwatani, Y. | 登録日 | 2018-02-02 | 公開日 | 2018-08-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of chimpanzee APOBEC3H dimerization stabilized by double-stranded RNA. Nucleic Acids Res., 46, 2018
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5BRO
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![BU of 5bro by Molmil](/molmil-images/mine/5bro) | Crystal structure of modified HexB (modB) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-hexosaminidase subunit beta, FORMIC ACID, ... | 著者 | Kitakaze, K, Maita, N, Itoh, K. | 登録日 | 2015-06-01 | 公開日 | 2016-05-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Protease-resistant modified human beta-hexosaminidase B ameliorates symptoms in GM2 gangliosidosis model. J.Clin.Invest., 126, 2016
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8WOW
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![BU of 8wow by Molmil](/molmil-images/mine/8wow) | Crystal structure of Arabidopsis thaliana UDP-glucose 4-epimerase 2 (AtUGE2) complexed with UDP, I160L/G233A mutant | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, UDP-glucose 4-epimerase 2, ... | 著者 | Matsumoto, M, Umezawa, A, Kotake, T, Fushinobu, S. | 登録日 | 2023-10-08 | 公開日 | 2024-05-15 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis. Plant J., 119, 2024
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8WOV
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![BU of 8wov by Molmil](/molmil-images/mine/8wov) | Crystal structure of Arabidopsis thaliana UDP-glucose 4-epimerase 2 (AtUGE2) complexed with UDP, G233A mutant | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase 2, URIDINE-5'-DIPHOSPHATE | 著者 | Matsumoto, M, Umezawa, A, Kotake, T, Fushinobu, S. | 登録日 | 2023-10-07 | 公開日 | 2024-05-15 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis. Plant J., 119, 2024
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8WOP
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![BU of 8wop by Molmil](/molmil-images/mine/8wop) | Crystal structure of Arabidopsis thaliana UDP-glucose 4-epimerase 2 (AtUGE2) complexed with UDP, wild-type | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase 2, URIDINE-5'-DIPHOSPHATE | 著者 | Matsumoto, M, Umezawa, A, Kotake, T, Fushinobu, S. | 登録日 | 2023-10-07 | 公開日 | 2024-05-08 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis. Plant J., 119, 2024
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6A6M
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![BU of 6a6m by Molmil](/molmil-images/mine/6a6m) | Crystal structure of an outward-open nucleotide-bound state of the eukaryotic ABC multidrug transporter CmABCB1 | 分子名称: | ATP-binding cassette, sub-family B, member 1, ... | 著者 | Kato, H, Nakatsu, T, Kodan, A. | 登録日 | 2018-06-28 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1. Nat Commun, 10, 2019
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6A6N
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![BU of 6a6n by Molmil](/molmil-images/mine/6a6n) | Crystal structure of an inward-open apo state of the eukaryotic ABC multidrug transporter CmABCB1 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-binding cassette, sub-family B, ... | 著者 | Kato, H, Nakatsu, T, Kodan, A. | 登録日 | 2018-06-28 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1. Nat Commun, 10, 2019
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3WUS
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![BU of 3wus by Molmil](/molmil-images/mine/3wus) | Crystal Structure of the Vif-Binding Domain of Human APOBEC3F | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3F, ZINC ION | 著者 | Nakashima, M, Kawamura, T, Ode, H, Watanabe, N, Iwatani, Y. | 登録日 | 2014-05-02 | 公開日 | 2015-06-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Structural Insights into HIV-1 Vif-APOBEC3F Interaction. J.Virol., 90, 2015
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