9MQT
 
 | | CryoEM Structure of the Candida albicans Group I Intron-Compound 11 Complex under Magnesium Condition | | 分子名称: | MAGNESIUM ION, N~4~-(2-aminoethyl)-N~4~-methylpyrimidine-2,4-diamine, POTASSIUM ION, ... | | 著者 | Chung, K, Xu, L, Liu, T, Pyle, A. | | 登録日 | 2025-01-06 | | 公開日 | 2025-04-30 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | | 主引用文献 | Molecular insights into de novo small-molecule recognition by an intron RNA structure.
Proc.Natl.Acad.Sci.USA, 122, 2025
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6M19
 | | Template lasso peptide C24 mutant W14F | | 分子名称: | lasso peptide | | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | | 登録日 | 2020-02-25 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.
Chem Sci, 12, 2021
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3S6T
 | | Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 V327G complexed with PUGNAc | | 分子名称: | N-acetylglucosaminidase, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE | | 著者 | Zhang, H, Liu, T, Yang, Q, Shen, X. | | 登録日 | 2011-05-26 | | 公開日 | 2012-04-11 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Active-pocket size differentiating insectile from bacterial chitinolytic beta-N-acetyl-D-hexosaminidases.
Biochem.J., 438, 2011
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3NSN
 | | Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with TMG-chitotriomycin | | 分子名称: | 2-deoxy-2-(trimethylammonio)-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetylglucosaminidase | | 著者 | Zhang, H, Liu, T, Liu, F, Yang, Q, Shen, X. | | 登録日 | 2010-07-02 | | 公開日 | 2010-11-24 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Determinants of an Insect {beta}-N-Acetyl-D-hexosaminidase Specialized as a Chitinolytic Enzyme
J.Biol.Chem., 286, 2011
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3OZP
 | | Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with PUGNAc | | 分子名称: | N-acetylglucosaminidase, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE | | 著者 | Zhang, H, Liu, T, Liu, F, Shen, X, Yang, Q. | | 登録日 | 2010-09-27 | | 公開日 | 2011-08-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Active-pocket size differentiating insectile from bacterial chitinolytic beta-N-acetyl-D-hexosaminidases
Biochem.J., 438, 2011
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3NSM
 | | Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 from Ostrinia furnacalis | | 分子名称: | N-acetylglucosaminidase | | 著者 | Zhang, H, Liu, T, Liu, F, Yang, Q, Shen, X. | | 登録日 | 2010-07-02 | | 公開日 | 2010-11-24 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Determinants of an Insect {beta}-N-Acetyl-D-hexosaminidase Specialized as a Chitinolytic Enzyme
J.Biol.Chem., 286, 2011
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4EBY
 | | Crystal structure of the ectodomain of a receptor like kinase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitin elicitor receptor kinase 1, ... | | 著者 | Chai, J, Liu, T, Han, Z, She, J, Wang, J. | | 登録日 | 2012-03-25 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Chitin-induced dimerization activates a plant immune receptor.
Science, 336, 2012
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4EBZ
 | | Crystal structure of the ectodomain of a receptor like kinase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitin elicitor receptor kinase 1, ... | | 著者 | Chai, J, Liu, T, Han, Z, She, J, Wang, J. | | 登録日 | 2012-03-26 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | | 主引用文献 | Chitin-induced dimerization activates a plant immune receptor.
Science, 336, 2012
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7BZ7
 | | Template lasso peptide C24 mutant F15Y | | 分子名称: | lasso peptide | | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | | 登録日 | 2020-04-27 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.
Chem Sci, 12, 2021
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7BZA
 | | Template lasso peptide C24 | | 分子名称: | lasso peptide | | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | | 登録日 | 2020-04-27 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.
Chem Sci, 12, 2021
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7BZ8
 | | Template lasso peptide C24 mutant V3A | | 分子名称: | lasso peptide | | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | | 登録日 | 2020-04-27 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.
Chem Sci, 12, 2021
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7BZ9
 | | Template lasso peptide C24 mutant I4A | | 分子名称: | lasso peptide | | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | | 登録日 | 2020-04-27 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications.
Chem Sci, 12, 2021
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8X3Y
 | | ThDP-dependent HKA synthase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BbmA, MAGNESIUM ION, ... | | 著者 | Yu, J.H, Liu, T. | | 登録日 | 2023-11-14 | | 公開日 | 2024-11-20 | | 最終更新日 | 2025-06-04 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural insights into two thiamine diphosphate-dependent enzymes and their synthetic applications in carbon-carbon linkage reactions.
Nat.Chem., 2025
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8X3Z
 | | ThDP-dependent HKA synthase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CsmA, MAGNESIUM ION, ... | | 著者 | Yu, J.H, Liu, T. | | 登録日 | 2023-11-14 | | 公開日 | 2024-11-20 | | 最終更新日 | 2025-06-04 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural insights into two thiamine diphosphate-dependent enzymes and their synthetic applications in carbon-carbon linkage reactions.
Nat.Chem., 2025
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8X3X
 | | ThDP-dependent HKA synthase | | 分子名称: | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ADENOSINE-5'-DIPHOSPHATE, BbmA, ... | | 著者 | Yu, J.H, Liu, T. | | 登録日 | 2023-11-14 | | 公開日 | 2024-11-20 | | 最終更新日 | 2025-06-04 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural insights into two thiamine diphosphate-dependent enzymes and their synthetic applications in carbon-carbon linkage reactions.
Nat.Chem., 2025
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8XOD
 | | ThDP-dependent HKA synthase | | 分子名称: | 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(~{R})-cyclobutyl(oxidanyl)methyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, ADENOSINE-5'-DIPHOSPHATE, BbmA-G484F complex with CBOA, ... | | 著者 | Yu, J.H, Liu, T. | | 登録日 | 2024-01-01 | | 公開日 | 2025-01-01 | | 最終更新日 | 2025-06-04 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural insights into two thiamine diphosphate-dependent enzymes and their synthetic applications in carbon-carbon linkage reactions.
Nat.Chem., 2025
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4D6V
 | | Crystal structure of signal transducing protein | | 分子名称: | G PROTEIN BETA SUBUNIT GIB2 | | 著者 | Ero, R, Dimitrova, V.T, Chen, Y, Bu, W, Feng, S, Liu, T, Wang, P, Xue, C, Tan, S.M, Gao, Y.G. | | 登録日 | 2014-11-17 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of Gib2, a Signal-Transducing Protein Scaffold Associated with Ribosomes in Cryptococcus Neoformans.
Sci.Rep., 5, 2015
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6LK3
 | | The Functional Characterization and Crystal Structure of Type II Peptidyl Carrier Protein ColA1a in Collismycins Biosynthesis | | 分子名称: | Putative free-standing acyl carrier protein | | 著者 | Ma, X.Y, Wang, G.Y, Liu, T, Chi, C.B, Zhang, Z.Y, Yang, D.H, Liu, W, Ma, M. | | 登録日 | 2019-12-18 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The functional characterization and crystal structure of type II peptidyl carrier protein ColA1a in collismycins biosynthesis.
Chin.J.Chem., 38, 2020
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3OZO
 | | Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with NGT | | 分子名称: | 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, N-acetylglucosaminidase | | 著者 | Zhang, H, Liu, T, Liu, F, Shen, X, Yang, Q. | | 登録日 | 2010-09-27 | | 公開日 | 2011-09-28 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with NGT
To be Published
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5GVX
 | | Structural insight into dephosphorylation by Trehalose 6-phosphate Phosphatase (OtsB2) from Mycobacterium Tuberculosis | | 分子名称: | MAGNESIUM ION, Trehalose-phosphate phosphatase | | 著者 | Shan, S, Min, H, Liu, T, Jiang, D, Rao, Z. | | 登録日 | 2016-09-07 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | | 主引用文献 | Structural insight into dephosphorylation by trehalose 6-phosphate phosphatase (OtsB2) from Mycobacterium tuberculosis.
FASEB J., 30, 2016
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5Y1B
 | | Crystal Structure of insect beta-N-acetyl-D-hexosaminidase OfHex1 complexed with a berberine derivative (SYSU-00679) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 9-O-3'-quinolinium propylberberine, Beta-hexosaminidase | | 著者 | Duan, Y.W, Liu, T, Zhou, Y, Tang, J.Y, Li, M, Yang, Q. | | 登録日 | 2017-07-20 | | 公開日 | 2018-01-24 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.207 Å) | | 主引用文献 | Glycoside hydrolase family 18 and 20 enzymes are novel targets of the traditional medicine berberine.
J. Biol. Chem., 293, 2018
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4F7Z
 | | Conformational dynamics of exchange protein directly activated by cAMP | | 分子名称: | GLYCEROL, Rap guanine nucleotide exchange factor 4 | | 著者 | White, M.A, Tsalkova, T.N, Mei, F.C, Liu, T, Woods, V.L, Cheng, X. | | 登録日 | 2012-05-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP.
Plos One, 7, 2012
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7XTZ
 | | Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-1 Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | 著者 | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | 登録日 | 2022-05-18 | | 公開日 | 2022-07-20 | | 最終更新日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
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7XU1
 | | Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-122 Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | 著者 | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | 登録日 | 2022-05-18 | | 公開日 | 2022-07-20 | | 最終更新日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
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7XU4
 | | Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | 著者 | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | 登録日 | 2022-05-18 | | 公開日 | 2022-07-20 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
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