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4W76
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Crystal Structure of Full-Length Split GFP Mutant D21H/K26C Disulfide and Metal-Mediated Dimer, P 21 21 21 Space Group, Form 2
分子名称: COPPER (II) ION, fluorescent protein D21H/K26C
著者Leibly, D.J, Waldo, G.S, Yeates, T.O.
登録日2014-08-21
公開日2015-02-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
4W7E
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BU of 4w7e by Molmil
Crystal Structure of Full-Length Split GFP Mutant E124H/K126H With Copper Mediated Crystal Contacts, P 41 21 2 Space Group
分子名称: COPPER (II) ION, IMIDAZOLE, fluorescent protein D21H/K26H
著者Leibly, D.J, Waldo, G.S, Yeates, T.O.
登録日2014-08-21
公開日2015-02-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.592 Å)
主引用文献A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
4W7R
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BU of 4w7r by Molmil
Crystal Structure of Full-Length Split GFP Mutant E124H/K126H Copper Mediated Dimer, P 21 Space Group
分子名称: 1,2-ETHANEDIOL, COPPER (II) ION, fluorescent protein E124H/K126C
著者Leibly, D.J, Waldo, G.S, Yeates, T.O.
登録日2014-08-22
公開日2015-03-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
4W6N
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BU of 4w6n by Molmil
Crystal Structure of Full-Length Split GFP Mutant D117C Disulfide Dimer, C 1 2 1 Space Group
分子名称: fluorescent protein D117C
著者Leibly, D.J, Waldo, G.S, Yeates, T.O.
登録日2014-08-20
公開日2015-02-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.375 Å)
主引用文献A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
4W72
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BU of 4w72 by Molmil
Crystal Structure of Full-Length Split GFP Mutant E115C/T118H Disulfide Dimer With Copper Mediated Crystal Contacts, P 21 21 21, Form 1
分子名称: COPPER (II) ION, fluorescent protein E115C/T118H
著者Leibly, D.J, Waldo, G.S, Yeates, T.O.
登録日2014-08-21
公開日2015-02-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
4W7C
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BU of 4w7c by Molmil
Crystal Structure of Full-Length Split GFP Mutant D21H/K26C Disulfide and Metal-Mediated Dimer, C 2 Space Group
分子名称: COPPER (II) ION, fluorescent protein D21H/K26C
著者Leibly, D.J, Waldo, G.S, Yeates, T.O.
登録日2014-08-21
公開日2015-03-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
4W7X
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BU of 4w7x by Molmil
Crystal Structure of Full-Length Split GFP Mutant E115C Disulfide Dimer, P 1 21 1 Space Group
分子名称: fluorescent protein E115C/T118H
著者Leibly, D.J, Waldo, G.S, Yeates, T.O.
登録日2014-08-22
公開日2015-03-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
4W6B
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BU of 4w6b by Molmil
Crystal Structure of a Superfolder GFP Mutant K26C Disulfide Dimer, P 21 21 21 Space Group
分子名称: CHLORIDE ION, MAGNESIUM ION, fluorescent protein K26C
著者Pashkov, I, Sawaya, M.R, Leibly, D.J, Waldo, G.S, Yeates, T.O.
登録日2014-08-20
公開日2015-02-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
5HPN
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BU of 5hpn by Molmil
A circularly permuted PduA forming an icosahedral cage
分子名称: Permuted PduA, SULFATE ION
著者Leibly, D.J, Jorda, J, Yeates, T.O.
登録日2016-01-20
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.509 Å)
主引用文献Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein.
Chem.Commun.(Camb.), 52, 2016
3GBZ
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BU of 3gbz by Molmil
Structure of the CMGC CDK Kinase from Giardia lamblia
分子名称: Kinase, CMGC CDK
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-02-20
公開日2009-03-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of a cyclin-dependent kinase from Giardia lamblia.
Acta Crystallogr.,Sect.F, 67, 2011
3GC0
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BU of 3gc0 by Molmil
Structure of the CMGC CDK Kinase from Giardia lamblia in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, Kinase, CMGC CDK
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-02-20
公開日2009-03-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a cyclin-dependent kinase from Giardia lamblia.
Acta Crystallogr.,Sect.F, 67, 2011
3LD9
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BU of 3ld9 by Molmil
Crystal structure of thymidylate kinase from Ehrlichia chaffeensis at 2.15A resolution
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate kinase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-01-12
公開日2010-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of thymidylate kinase from Ehrlichia chaffeensis.
Acta Crystallogr.,Sect.F, 67, 2011
4ONA
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BU of 4ona by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1517
分子名称: 5-amino-1-tert-butyl-3-(7-ethoxyquinolin-3-yl)-1H-pyrazole-4-carboxamide, Calmodulin-domain protein kinase 1
著者Merritt, E.A.
登録日2014-01-28
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Potent and selective inhibitors of CDPK1 from T. gondii and C. parvum based on a 5-aminopyrazole-4-carboxamide scaffold.
ACS Med Chem Lett, 5, 2014
4TZR
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BU of 4tzr by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1561
分子名称: 1-{4-amino-3-[2-(cyclopropyloxy)quinolin-6-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}-2-methylpropan-2-ol, Calmodulin-domain protein kinase 1
著者Merritt, E.A.
登録日2014-07-10
公開日2014-08-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.
J. Med. Chem., 59, 2016
4FDZ
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BU of 4fdz by Molmil
EutL from Clostridium perfringens, Crystallized Under Reducing Conditions
分子名称: Ethanolamine utilization protein, SODIUM ION
著者Thompson, M.C, Cascio, D, Crowley, C.S, Kopstein, J.S, Yeates, T.O.
登録日2012-05-29
公開日2013-05-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献An allosteric model for control of pore opening by substrate binding in the EutL microcompartment shell protein.
Protein Sci., 24, 2015
3KRS
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BU of 3krs by Molmil
Structure of Triosephosphate Isomerase from Cryptosporidium Parvum at 1.55A Resolution
分子名称: SODIUM ION, Triosephosphate isomerase, UNKNOWN ATOM OR ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-11-19
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of triosephosphate isomerase from Cryptosporidium parvum.
Acta Crystallogr.,Sect.F, 67, 2011
4WG4
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BU of 4wg4 by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1613
分子名称: 3-(7-ethoxynaphthalen-2-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
著者Merritt, E.A.
登録日2014-09-17
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1613
to be published
3SXF
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BU of 3sxf by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-89
分子名称: 1,2-ETHANEDIOL, 3-(6-ethoxynaphthalen-2-yl)-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1, ...
著者Larson, E.T, Merritt, E.A.
登録日2011-07-14
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1.
J.Med.Chem., 55, 2012
3SX9
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Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-132
分子名称: 3-(6-ethoxynaphthalen-2-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
著者Larson, E.T, Merritt, E.A.
登録日2011-07-14
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1.
J.Med.Chem., 55, 2012
3T3U
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BU of 3t3u by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-130
分子名称: 1,2-ETHANEDIOL, 3-(6-methoxynaphthalen-2-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1, ...
著者Larson, E.T, Merritt, E.A.
登録日2011-07-25
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1.
J.Med.Chem., 55, 2012
3T3V
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BU of 3t3v by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-87
分子名称: 1,2-ETHANEDIOL, 3-(6-methoxynaphthalen-2-yl)-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
著者Larson, E.T, Merritt, E.A.
登録日2011-07-25
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1.
J.Med.Chem., 55, 2012
4JBV
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BU of 4jbv by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1268
分子名称: 1-[(1-methylpiperidin-4-yl)methyl]-3-[6-(2-methylpropoxy)naphthalen-2-yl]pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
著者Merritt, E.A, Larson, E.T.
登録日2013-02-20
公開日2014-03-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes.
Eur.J.Med.Chem., 74, 2014
4M84
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BU of 4m84 by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455
分子名称: 5-amino-1-tert-butyl-3-(quinolin-2-yl)-1H-pyrazole-4-carboxamide, Calmodulin-domain protein kinase 1
著者Merritt, E.A.
登録日2013-08-12
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Potent and selective inhibitors of CDPK1 from T. gondii and C. parvum based on a 5-aminopyrazole-4-carboxamide scaffold.
ACS Med Chem Lett, 5, 2014
4WG5
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BU of 4wg5 by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1647
分子名称: 5-amino-3-[7-(cyclobutyloxy)quinolin-3-yl]-1-cyclohexyl-1H-pyrazole-4-carboxamide, Calmodulin-domain protein kinase 1
著者Merritt, E.A.
登録日2014-09-17
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1647
to be published
4Y5Q
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Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, CALCIUM ION, Calmodulin-domain protein kinase 1, ...
著者Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2015-02-11
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP
To Be Published

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