2EPM
 
 | | N-acetyl-B-D-glucoasminidase (GCNA) from Stretococcus gordonii | | 分子名称: | GLYCEROL, MERCURY (II) ION, N-acetyl-beta-D-glucosaminidase, ... | | 著者 | Langley, D.B, Harty, D.W.S, Guss, J.M, Collyer, C.A. | | 登録日 | 2007-03-30 | | 公開日 | 2008-03-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline
J.Mol.Biol., 377, 2008
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2CFK
 | | AGAO in complex with wc5 (Ru-wire inhibitor, 5-carbon linker) | | 分子名称: | COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ... | | 著者 | Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B. | | 登録日 | 2006-02-21 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Enantiomer-specific binding of ruthenium(II) molecular wires by the amine oxidase of Arthrobacter globiformis.
J. Am. Chem. Soc., 130, 2008
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2EPK
 | | N-acetyl-B-D-glucosaminidase (GCNA) from Streptococcus gordonii | | 分子名称: | N-acetyl-beta-D-glucosaminidase, SULFATE ION | | 著者 | Langley, D.B. | | 登録日 | 2007-03-30 | | 公開日 | 2008-03-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline
J.Mol.Biol., 377, 2008
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1DUV
 | | CRYSTAL STRUCTURE OF E. COLI ORNITHINE TRANSCARBAMOYLASE COMPLEXED WITH NDELTA-L-ORNITHINE-DIAMINOPHOSPHINYL-N-SULPHONIC ACID (PSORN) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, NDELTA-(N'-SULPHODIAMINOPHOSPHINYL)-L-ORNITHINE, ORNITHINE TRANSCARBAMOYLASE | | 著者 | Langley, D.B, Templeton, M.D, Fields, B.A, Mitchell, R.E, Collyer, C.A. | | 登録日 | 2000-01-18 | | 公開日 | 2000-07-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism of inactivation of ornithine transcarbamoylase by Ndelta -(N'-Sulfodiaminophosphinyl)-L-ornithine, a true transition state analogue? Crystal structure and implications for catalytic mechanism.
J.Biol.Chem., 275, 2000
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7MSQ
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7T72
 | | Epitope-based selection of SARS-CoV-2 neutralizing antibodies from convalescent patients | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ... | | 著者 | Langley, D.B, Christ, D, Rouet, R. | | 登録日 | 2021-12-14 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.177 Å) | | 主引用文献 | Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.
Nat Commun, 14, 2023
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2ZP2
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7KZC
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7KZA
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7KZB
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6DSI
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6DN0
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8DXU
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8DXT
 | | Fab arm of antibody GAR12 bound to the receptor binding domain of SARS-CoV-2. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab arm of antibody GAR12, Light chain of Fab arm of antibody GAR12, ... | | 著者 | Langley, D.B, Christ, D, Henry, J.Y. | | 登録日 | 2022-08-03 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.
Nat Commun, 14, 2023
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6P4C
 | | HyHEL10 Fab carrying four heavy chain mutations (HyHEL10-4x): L4F, Y33H, S56N, and Y58F | | 分子名称: | CHLORIDE ION, HyHEL10 Fab heavy chain, HyHEL10 Fab light chain | | 著者 | Langley, D.B, Christ, D. | | 登録日 | 2019-05-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6P4B
 | | HyHEL10 fab variant HyHEL10-4x (heavy chain mutations L4F, Y33H, S56N, and Y58F) bound to hen egg lysozyme variant HEL2x-flex (mutations R21Q, R73E, C76S, and C94S) | | 分子名称: | CHLORIDE ION, HyHEL10 Fab heavy chain, HyHEL10 Fab light chain, ... | | 著者 | Langley, D.B, Christ, D. | | 登録日 | 2019-05-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6P4D
 | | Hen egg lysozyme (HEL) containing three point mutations (HEL3x): R21Q, R73E, and D101R | | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme C, ... | | 著者 | Langley, D.B, Christ, D. | | 登録日 | 2019-05-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6P4A
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1W5Z
 | | AGAO covalent complex with Benzylhydrazine | | 分子名称: | COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ... | | 著者 | Duff, A.P, Trambaiolo, D.M, Langley, D.B, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M. | | 登録日 | 2004-08-11 | | 公開日 | 2005-12-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Complexes of the Copper-Containing Amine Oxidase from Arthrobacter Globiformis with the Inhibitors Benzylhydrazine and Tranylcypromine.
Acta Crystallogr.,Sect.F, 64, 2008
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1W4N
 | | AGAO covalent complex with Tranylcypromine | | 分子名称: | COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ... | | 著者 | Duff, A.P, Trambaiolo, D.M, Langley, D.B, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M. | | 登録日 | 2004-07-27 | | 公開日 | 2005-12-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Complexes of the Copper-Containing Amine Oxidase from Arthrobacter Globiformis with the Inhibitors Benzylhydrazine and Tranylcypromine.
Acta Crystallogr.,Sect.F, 64, 2008
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4N1C
 | | Structural evidence for antigen receptor evolution | | 分子名称: | Lysozyme C, immunoglobulin variable light chain domain | | 著者 | Langley, D.B, Rouet, R, Roome, B, Stock, D, Christ, D. | | 登録日 | 2013-10-03 | | 公開日 | 2014-10-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural reconstruction of protein ancestry.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4N1E
 | | Structural evidence for antigen receptor evolution | | 分子名称: | Lysozyme C, immunoglobulin variable light chain domain | | 著者 | Langley, D.B, Rouet, R, Stock, D, Christ, D. | | 登録日 | 2013-10-04 | | 公開日 | 2014-10-29 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Structural reconstruction of protein ancestry.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V3B
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5V3P
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1W6C
 | | AGAO holoenzyme in a small cell, at 2.2 angstroms | | 分子名称: | COPPER (II) ION, PHENYLETHYLAMINE OXIDASE, SODIUM ION | | 著者 | Duff, A.P, Langley, D.B, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M. | | 登録日 | 2004-08-17 | | 公開日 | 2005-12-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Copper Containing Amine Oxidase from Arthrobacter Globiformis: Refinement at 1.55 And 2.20 A Resolution in Two Crystal Forms.
Acta Crystallogr.,Sect.F, 62, 2006
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