3PN3
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![BU of 3pn3 by Molmil](/molmil-images/mine/3pn3) | Crystal structure of Arabidopsis thaliana petide deformylase 1B (AtPDF1B) in complex with inhibitor 21 | 分子名称: | Peptide deformylase 1B, chloroplastic, ZINC ION, ... | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | 登録日 | 2010-11-18 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Trapping conformational States along ligand-binding dynamics of Peptide deformylase: the impact of induced fit on enzyme catalysis. Plos Biol., 9, 2011
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4JE6
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![BU of 4je6 by Molmil](/molmil-images/mine/4je6) | Crystal structure of a human-like mitochondrial peptide deformylase | 分子名称: | Peptide deformylase 1A, chloroplastic/mitochondrial, ZINC ION | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | 登録日 | 2013-02-26 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart. Acta Crystallogr.,Sect.D, 70, 2014
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4JE8
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![BU of 4je8 by Molmil](/molmil-images/mine/4je8) | Crystal structure of a human-like mitochondrial peptide deformylase in complex with Met-Ala-Ser | 分子名称: | Peptide deformylase 1A, chloroplastic/mitochondrial, ZINC ION, ... | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | 登録日 | 2013-02-26 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart. Acta Crystallogr.,Sect.D, 70, 2014
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1ZY1
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![BU of 1zy1 by Molmil](/molmil-images/mine/1zy1) | X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A) in complex with Met-Ala-Ser | 分子名称: | Peptide deformylase, mitochondrial, ZINC ION, ... | 著者 | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | 登録日 | 2005-06-09 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms J.Biol.Chem., 280, 2005
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4JE7
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![BU of 4je7 by Molmil](/molmil-images/mine/4je7) | Crystal structure of a human-like mitochondrial peptide deformylase in complex with actinonin | 分子名称: | ACTINONIN, Peptide deformylase 1A, chloroplastic/mitochondrial, ... | 著者 | Fieulaine, S, Meinnel, T, Giglione, C. | 登録日 | 2013-02-26 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart. Acta Crystallogr.,Sect.D, 70, 2014
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1ZXZ
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![BU of 1zxz by Molmil](/molmil-images/mine/1zxz) | X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A); crystals grown in PEG-5000 MME as precipitant | 分子名称: | Peptide deformylase, mitochondrial, ZINC ION | 著者 | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | 登録日 | 2005-06-09 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms J.Biol.Chem., 280, 2005
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1ZY0
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![BU of 1zy0 by Molmil](/molmil-images/mine/1zy0) | X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A); crystals grown in PEG-6000 | 分子名称: | Peptide deformylase, mitochondrial, ZINC ION | 著者 | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | 登録日 | 2005-06-09 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms J.Biol.Chem., 280, 2005
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1U2T
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![BU of 1u2t by Molmil](/molmil-images/mine/1u2t) | X-Ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp. PCC6803 in complex with sucrose6P | 分子名称: | 6-O-phosphono-beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, sucrose-phosphatase (SPP) | 著者 | Fieulaine, S, Lunn, J.E, Borel, F, Ferrer, J.-L. | 登録日 | 2004-07-20 | 公開日 | 2005-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell PLANT CELL, 17, 2005
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1S2O
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![BU of 1s2o by Molmil](/molmil-images/mine/1s2o) | X-Ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp. PCC6803 at 1.40 A resolution | 分子名称: | MAGNESIUM ION, sucrose-phosphatase | 著者 | Fieulaine, S, Lunn, J.E, Borel, F, Ferrer, J.L. | 登録日 | 2004-01-09 | 公開日 | 2005-02-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell. Plant Cell, 17, 2005
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1U2S
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![BU of 1u2s by Molmil](/molmil-images/mine/1u2s) | X-Ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp. PCC6803 in complex with glucose | 分子名称: | MAGNESIUM ION, alpha-D-glucopyranose, sucrose-phosphatase | 著者 | Fieulaine, S, Lunn, J.E, Borel, F, Ferrer, J.-L. | 登録日 | 2004-07-20 | 公開日 | 2005-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell PLANT CELL, 17, 2005
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2B1R
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![BU of 2b1r by Molmil](/molmil-images/mine/2b1r) | |
2B1Q
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![BU of 2b1q by Molmil](/molmil-images/mine/2b1q) | |
1TJ3
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![BU of 1tj3 by Molmil](/molmil-images/mine/1tj3) | X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in a closed conformation | 分子名称: | MAGNESIUM ION, Sucrose-Phosphatase | 著者 | Fieulaine, S, Lunn, J.E, Borel, F, Ferrer, J.-L. | 登録日 | 2004-06-03 | 公開日 | 2005-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell. Plant Cell, 17, 2005
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2D2V
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1TJ4
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![BU of 1tj4 by Molmil](/molmil-images/mine/1tj4) | X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in complex with sucrose | 分子名称: | MAGNESIUM ION, Sucrose-Phosphatase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | 著者 | Fieulaine, S, Lunn, J.E, Borel, F, Ferrer, J.-L. | 登録日 | 2004-06-03 | 公開日 | 2005-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell. Plant Cell, 17, 2005
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1TJ5
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![BU of 1tj5 by Molmil](/molmil-images/mine/1tj5) | X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in complex with sucrose and phosphate | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, Sucrose-Phosphatase, ... | 著者 | Fieulaine, S, Lunn, J.E, Borel, F, Ferrer, J.-L. | 登録日 | 2004-06-03 | 公開日 | 2005-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell. Plant Cell, 17, 2005
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5MTE
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![BU of 5mte by Molmil](/molmil-images/mine/5mte) | Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T in complex with actinonin - crystal form II | 分子名称: | ACTINONIN, NICKEL (II) ION, Putative uncharacterized protein orf60T, ... | 著者 | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | 登録日 | 2017-01-09 | 公開日 | 2017-11-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Peptide deformylases from Vibrio parahaemolyticus phage and bacteria display similar deformylase activity and inhibitor binding clefts. Biochim. Biophys. Acta, 1866, 2018
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3SVL
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![BU of 3svl by Molmil](/molmil-images/mine/3svl) | Structural basis of the improvement of ChrR - a multi-purpose enzyme | 分子名称: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, protein yieF | 著者 | Poulain, S, Eswaramoorthy, S, Hienerwadel, R, Bremond, N, Sylvester, M.D, Zhang, Y.B, Van Der Lelie, D, Berthomieu, C, Matin, A.C. | 登録日 | 2011-07-12 | 公開日 | 2012-05-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of ChrR-A Quinone Reductase with the Capacity to Reduce Chromate. Plos One, 7, 2012
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5MTC
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![BU of 5mtc by Molmil](/molmil-images/mine/5mtc) | Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form I | 分子名称: | NICKEL (II) ION, Putative uncharacterized protein orf60T, ZINC ION | 著者 | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | 登録日 | 2017-01-09 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
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5MTD
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![BU of 5mtd by Molmil](/molmil-images/mine/5mtd) | Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form II | 分子名称: | NICKEL (II) ION, Putative uncharacterized protein orf60T, TRIETHYLENE GLYCOL, ... | 著者 | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | 登録日 | 2017-01-09 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
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2OPE
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![BU of 2ope by Molmil](/molmil-images/mine/2ope) | Crystal structure of the Neisseria meningitidis minor Type IV pilin, PilX, in space group P43 | 分子名称: | PilX | 著者 | Dyer, D.H, Helaine, S, Pelicic, V, Forest, K.T. | 登録日 | 2007-01-29 | 公開日 | 2007-10-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | 3D structure/function analysis of PilX reveals how minor pilins can modulate the virulence properties of type IV pili. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2OPD
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![BU of 2opd by Molmil](/molmil-images/mine/2opd) | Structure of the Neisseria meningitidis minor Type IV pilin, PilX | 分子名称: | PilX | 著者 | Dyer, D.H, Helaine, S, Pelicic, V, Forest, K.T. | 登録日 | 2007-01-29 | 公開日 | 2007-10-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | 3D structure/function analysis of PilX reveals how minor pilins can modulate the virulence properties of type IV pili. Proc.Natl.Acad.Sci.Usa, 104, 2007
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6ET4
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![BU of 6et4 by Molmil](/molmil-images/mine/6et4) | HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH NOVEL INHIBITOR | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, ACETIC ACID, CHLORIDE ION, ... | 著者 | Hakansson, M, Walse, B, Gustavsson, A.-L, Lain, S. | 登録日 | 2017-10-25 | 公開日 | 2018-03-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage. Nat Commun, 9, 2018
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6GK0
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![BU of 6gk0 by Molmil](/molmil-images/mine/6gk0) | HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH CLASS III HISTONE DEACETYLASE INHIBITOR | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, 4-~{tert}-butyl-~{N}-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide, ACETIC ACID, ... | 著者 | Hakansson, M, Ladds, M.J.G.W, Walse, B, Lain, S. | 登録日 | 2018-05-17 | 公開日 | 2019-11-27 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology. J.Biol.Chem., 295, 2020
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7ZG6
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![BU of 7zg6 by Molmil](/molmil-images/mine/7zg6) | TacA1 antitoxin | 分子名称: | DUF1778 domain-containing protein, MAGNESIUM ION | 著者 | Grabe, G.J, Morgan, R.M.L, Helaine, S. | 登録日 | 2022-04-01 | 公開日 | 2023-10-11 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Molecular stripping underpins derepression of a toxin-antitoxin system. Nat.Struct.Mol.Biol., 2024
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