8D1F
 
 | | hBest2 5mM Ca2+ (Ca2+-bound) closed state | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, Bestrophin-2, ... | | 著者 | Owji, A.P, Kittredge, A, Hendrickson, W.A, Tingting, Y. | | 登録日 | 2022-05-27 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (1.82 Å) | | 主引用文献 | Structures and gating mechanisms of human bestrophin anion channels.
Nat Commun, 13, 2022
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8D1N
 | | bBest2_345 Ca2+-bound open state | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, Bestrophin, ... | | 著者 | Owji, A.P, Kittredge, A, Hendrickson, W.A, Tingting, Y. | | 登録日 | 2022-05-27 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (1.93 Å) | | 主引用文献 | Structures and gating mechanisms of human bestrophin anion channels.
Nat Commun, 13, 2022
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8D1E
 | | hBest2 1uM Ca2+ (Ca2+-bound) closed state | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, Bestrophin-2, ... | | 著者 | Owji, A.P, Kittredge, A, Hendrickson, W.A, Tingting, Y. | | 登録日 | 2022-05-27 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (1.78 Å) | | 主引用文献 | Structures and gating mechanisms of human bestrophin anion channels.
Nat Commun, 13, 2022
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8D1L
 | | hBest1 Ca2+-bound partially open aperture state | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Bestrophin-1, CALCIUM ION, ... | | 著者 | Owji, A.P, Kittredge, A, Hendrickson, W.A, Tingting, Y. | | 登録日 | 2022-05-27 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | | 主引用文献 | Structures and gating mechanisms of human bestrophin anion channels.
Nat Commun, 13, 2022
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8D1M
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8D1J
 | | hBest1 5mM Ca2+ (Ca2+-bound) closed state | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Bestrophin-1, CALCIUM ION | | 著者 | Owji, A.P, Kittredge, A, Hendrickson, W.A, Tingting, Y. | | 登録日 | 2022-05-27 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (2.05 Å) | | 主引用文献 | Structures and gating mechanisms of human bestrophin anion channels.
Nat Commun, 13, 2022
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8D1H
 | | hBest2 Ca2+-unbound closed state | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, Bestrophin-2, ... | | 著者 | Owji, A.P, Kittredge, A, Hendrickson, W.A, Tingting, Y. | | 登録日 | 2022-05-27 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (1.94 Å) | | 主引用文献 | Structures and gating mechanisms of human bestrophin anion channels.
Nat Commun, 13, 2022
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5X87
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8ECY
 | | cryoEM structure of bovine bestrophin-2 and glutamine synthetase complex | | 分子名称: | Bestrophin, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Owji, A.P, Kittredge, A.K, Yang, T. | | 登録日 | 2022-09-02 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2 Å) | | 主引用文献 | Bestrophin-2 and glutamine synthetase form a complex for glutamate release.
Nature, 611, 2022
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