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CryoEM structure of Western equine encephalitis virus VLP in complex with the chimeric Du-D1-Mo-D2 MXRA8 receptor
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, DuD1MoD2 chimeric MXRA8, E1 envelope glycoprotein, ...
著者	Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日	2023-05-04
公開日	2023-12-20
実験手法	ELECTRON MICROSCOPY (3.89 Å)
主引用文献	Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8. Cell, 186, 2023

6XO4

CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP
分子名称:	Togavirin
著者	Binshtein, E, Crowe, J.E.
登録日	2020-07-06
公開日	2020-12-23
最終更新日	2021-01-13
実験手法	ELECTRON MICROSCOPY (4.2 Å)
主引用文献	Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection. Cell, 183, 2020

6XOB

CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP with Fab EEEV-143.
分子名称:	EEEV-143 Fab heavy chain, EEEV-143 Fab light chain, Togavirin
著者	Binshtein, E, Crowe, J.E.
登録日	2020-07-06
公開日	2020-12-23
最終更新日	2021-01-13
実験手法	ELECTRON MICROSCOPY (8.5 Å)
主引用文献	Human Antibodies Protect against Aerosolized Eastern Equine Encephalitis Virus Infection. Cell, 183, 2020

8DAQ

CryoEM structure of Western equine encephalitis virus VLP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein
著者	Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日	2022-06-13
公開日	2023-12-20
実験手法	ELECTRON MICROSCOPY (4.35 Å)
主引用文献	Alternate repeat domain usage in an alphavirus entry receptor enables host species expansion To Be Published

8DAN

CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, E1 envelope glycoprotein, E2 envelope glycoprotein, ...
著者	Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日	2022-06-13
公開日	2023-12-20
実験手法	ELECTRON MICROSCOPY (4.74 Å)
主引用文献	Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion To Be Published

5AWN

Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC176 Fab
分子名称:	Heavy chain of 3BC176 Fab, Light chain of 3BC176 Fab
著者	Lee, J.H, Wilson, I.A, Ward, A.B.
登録日	2015-07-06
公開日	2015-11-11
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (1.887 Å)
主引用文献	Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nat Commun, 6, 2015

5CCK

Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC315 Fab
分子名称:	3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Antibody 3BC315 Fab heavy chain, Antibody 3BC315 Fab light chain
著者	Lee, J.H, Ward, A.B, Wilson, I.A.
登録日	2015-07-02
公開日	2015-10-07
最終更新日	2019-12-11
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nat Commun, 6, 2015

6CRJ

Mouse norovirus model using the crystal structure of MNV P domain and the Norwalkvirus shell domain
分子名称:	Norwalk virus, MNV-1 capsid protein chimera
著者	Smith, T.J.
登録日	2018-03-19
公開日	2018-04-04
最終更新日	2024-03-13
実験手法	ELECTRON MICROSCOPY (8 Å)
主引用文献	Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

6C6Q

Crystal Structure of the Murine Norovirus VP1 P Domain in complex with the CD300lf Receptor
分子名称:	1,2-ETHANEDIOL, CHLORIDE ION, CMRF35-like molecule 1, ...
著者	Nelson, C.A, Fremont, D.H.
登録日	2018-01-19
公開日	2018-09-12
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

6C74

Crystal Structure of Murine CD300lf in complex with phosphocholine
分子名称:	CALCIUM ION, CMRF35-like molecule-1, PHOSPHOCHOLINE
著者	Nelson, C.A, Fremont, D.H.
登録日	2018-01-19
公開日	2018-09-12
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.358 Å)
主引用文献	Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

6W2U

Mayaro Virus glycoprotein E1 ectodomain and glycoportien E2 ectodomain asymmetric unit
分子名称:	Spike glycoprotein E1, Spike glycoprotein E2
著者	Miller, A.S, Kuhn, R.J.
登録日	2020-03-08
公開日	2020-10-07
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (4.8 Å)
主引用文献	Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host Microbe, 28, 2020

6VYV

Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
分子名称:	E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ...
著者	Miller, A.S, Kuhn, R.J.
登録日	2020-02-27
公開日	2020-08-26
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (6.33 Å)
主引用文献	Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host Microbe, 28, 2020

6W09

Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
分子名称:	E1 glycoprotein, E2 glycoprotein, E3, ...
著者	Miller, A.S, Kuhn, R.J.
登録日	2020-02-29
公開日	2020-08-26
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (5.3 Å)
主引用文献	Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host Microbe, 28, 2020

6W1C

Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
分子名称:	E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ...
著者	Miller, A.S, Kuhn, R.J.
登録日	2020-03-04
公開日	2020-08-26
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (5.3 Å)
主引用文献	Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host Microbe, 28, 2020

8EWF

CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Chimeric MXRA8 receptor: D1 from Duck MXRA8 and D2 from Mouse MXRA8, E1 envelope protein, ...
著者	Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
登録日	2022-10-22
公開日	2023-10-25
実験手法	ELECTRON MICROSCOPY (3.92 Å)
主引用文献	Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion To Be Published

6NK5

Electron Cryo-Microscopy Of Chikungunya VLP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ...
著者	Basore, K, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日	2019-01-04
公開日	2019-05-22
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (4.16 Å)
主引用文献	Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor. Cell, 177, 2019

6O3G

Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41).
分子名称:	GLYCEROL, MEPER peptide, region 671-683 of HIV-1 gp41, ...
著者	Irimia, A, Wilson, I.A.
登録日	2019-02-26
公開日	2019-12-04
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (3.645 Å)
主引用文献	An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019

6O3K

Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3
分子名称:	GLYCEROL, PGZL1.H4K3 heavy chain, PGZL1.H4K3 light chain, ...
著者	Irimia, A, Wilson, I.A.
登録日	2019-02-26
公開日	2019-12-04
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (1.451 Å)
主引用文献	An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019

6O3U

Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with 06:0 PA
分子名称:	(2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, GLYCEROL, PGZL1.H4K3 heavy chain, ...
著者	Irimia, A, Wilson, I.A.
登録日	2019-02-27
公開日	2019-12-04
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (3.105 Å)
主引用文献	An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019

6O3D

Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.
分子名称:	GLYCEROL, PGZL1 FAB HEAVY CHAIN, PGZL1 FAB LIGHT CHAIN, ...
著者	Irimia, A, Wilson, I.A.
登録日	2019-02-26
公開日	2019-12-04
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (1.402 Å)
主引用文献	An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019

6O3J

Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41) and phosphatidic acid (06:0 PA)
分子名称:	(2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, (4S)-2-METHYL-2,4-PENTANEDIOL, MPER peptide, ...
著者	Irimia, A, Wilson, I.A.
登録日	2019-02-26
公開日	2019-12-04
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (3.416 Å)
主引用文献	An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019

6O3L

Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41).
分子名称:	GLYCEROL, MPER peptide, region 671-683 of HIV-1 gp41, ...
著者	Irimia, A, Wilson, I.A.
登録日	2019-02-26
公開日	2019-12-04
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (1.98 Å)
主引用文献	An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019

6O41

Crystal structure of the unbound PGZL1 germline Fab fragment (PGZL1_gVmDmJ)
分子名称:	GLYCEROL, Immunoglobulin G-binding protein G (DOMAIN III), germline PGZL1_gVmDmJ heavy chain, ...
著者	Irimia, A, Wilson, I.A.
登録日	2019-02-27
公開日	2019-12-04
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.465 Å)
主引用文献	An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019

7SFW

CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP in complex with Fab hVEEV-63 (focus refine of the asymmetric unit)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Spike glycoprotein E1, ...
著者	Binshtein, E, Crowe, J.E.
登録日	2021-10-04
公開日	2022-03-16
最終更新日	2022-07-06
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. J.Exp.Med., 219, 2022

7SFU

CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Spike glycoprotein E1, ...
著者	Binshtein, E, Crowe, J.E.
登録日	2021-10-04
公開日	2022-03-16
最終更新日	2022-07-06
実験手法	ELECTRON MICROSCOPY (4.2 Å)
主引用文献	Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. J.Exp.Med., 219, 2022

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