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SOS2 crystal structure with fragment bound (compound 13)
分子名称:	4-(aminomethyl)benzene-1-sulfonamide, SULFATE ION, Son of sevenless homolog 2
著者	Gunn, R.J, Lawson, J.D, Ivetac, A, Ulaganathan, T, Coulombe, R, Fethiere, J.
登録日	2023-06-14
公開日	2024-01-10
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (2.12 Å)
主引用文献	Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. J.Med.Chem., 67, 2024

Apo SOS2 crystal structure in P1 space group
分子名称:	SULFATE ION, Son of sevenless homolog 2
著者	Gunn, R.J, Lawson, J.D.
登録日	2023-10-03
公開日	2024-01-10
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. J.Med.Chem., 67, 2024

SOS2 co-crystal structure with fragment bound (compound 10)
分子名称:	8-hydroxyquinoline-2-carbonitrile, Son of sevenless homolog 2
著者	Gunn, R.J, Lawson, J.D.
登録日	2023-10-06
公開日	2024-01-10
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.73 Å)
主引用文献	Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. J.Med.Chem., 67, 2024

SOS2 co-crystal structure with fragment bound (compound 9)
分子名称:	7-chloroquinolin-4-amine, Son of sevenless homolog 2
著者	Gunn, R.J, Lawson, J.D.
登録日	2023-09-26
公開日	2024-01-10
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (2.44 Å)
主引用文献	Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. J.Med.Chem., 67, 2024