Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2H8M
DownloadVisualize
BU of 2h8m by Molmil
N-Domain Of Grp94 In Complex With the 2-Iodo-NECA
分子名称: (2S,3S,4R,5R)-5-(6-AMINO-2-IODO-9H-PURIN-9-YL)-N-ETHYL-3,4-DIHYDROXYTETRAHYDROFURAN-2-CARBOXAMIDE, Endoplasmin, PENTAETHYLENE GLYCOL, ...
著者Immormino, R.M, Gewirth, D.T.
登録日2006-06-07
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献N-Domain Of Grp94 In Complex With the 2-Iodo-NECA
To be Published
2EXL
DownloadVisualize
BU of 2exl by Molmil
GRP94 N-terminal Domain bound to geldanamycin
分子名称: Endoplasmin, GELDANAMYCIN, PENTAETHYLENE GLYCOL, ...
著者Reardon, P.N, Immormino, R.M, Gewirth, D.T.
登録日2005-11-08
公開日2006-10-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
J.Mol.Biol., 388, 2009
1TBW
DownloadVisualize
BU of 1tbw by Molmil
Ligand Induced Conformational Shift in the N-terminal Domain of GRP94, Open Conformation
分子名称: ADENOSINE MONOPHOSPHATE, Endoplasmin, MAGNESIUM ION, ...
著者Gewirth, D.T, Immormino, R.M, Dollins, D.E, Shaffer, P.L, Walker, M.A, Soldano, K.L.
登録日2004-05-20
公開日2004-08-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Ligand-induced Conformational Shift in the N-terminal Domain of GRP94, an Hsp90 Chaperone.
J.Biol.Chem., 279, 2004
1TC0
DownloadVisualize
BU of 1tc0 by Molmil
Ligand Induced Conformational Shifts in the N-terminal Domain of GRP94, Open Conformation Complexed with the physiological partner ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Endoplasmin, MAGNESIUM ION, ...
著者Gewirth, D.T, Immormino, R.M, Dollins, D.E, Shaffer, P.L, Walker, M.A, Soldano, K.L.
登録日2004-05-20
公開日2004-08-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ligand-induced Conformational Shift in the N-terminal Domain of GRP94, an Hsp90 Chaperone.
J.Biol.Chem., 279, 2004
1TC6
DownloadVisualize
BU of 1tc6 by Molmil
Ligand Induced Conformational Shift in the N-terminal Domain of GRP94, Open Conformation ADP-Complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION, ...
著者Gewirth, D.T, Immormino, R.M, Dollins, D.E, Shaffer, P.L, Walker, M.A, Soldano, K.L.
登録日2004-05-20
公開日2004-08-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Ligand-induced Conformational Shift in the N-terminal Domain of GRP94, an Hsp90 Chaperone.
J.Biol.Chem., 279, 2004
3RVP
DownloadVisualize
BU of 3rvp by Molmil
Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89K
分子名称: BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein CheY, GLYCEROL, ...
著者Starbird, C.A, Immormino, R.M, Silversmith, R.E, Bourret, R.B.
登録日2011-05-06
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.404 Å)
主引用文献Probing Mechanistic Similarities between Response Regulator Signaling Proteins and Haloacid Dehalogenase Phosphatases.
Biochemistry, 54, 2015
3RVM
DownloadVisualize
BU of 3rvm by Molmil
Structure of the CheY-Mn2+ Complex with substitutions at 59 and 89: N59D and E89R
分子名称: Chemotaxis protein CheY, MANGANESE (II) ION
著者Starbird, C.A, Immormino, R.M, Silversmith, R.E, Bourret, R.B.
登録日2011-05-06
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Probing Mechanistic Similarities between Response Regulator Signaling Proteins and Haloacid Dehalogenase Phosphatases.
Biochemistry, 54, 2015
3RVJ
DownloadVisualize
BU of 3rvj by Molmil
Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89Q
分子名称: BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein CheY, GLYCEROL, ...
著者Starbird, C.A, Immormino, R.M, Silversmith, R.E, Bourret, R.B.
登録日2011-05-06
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Probing Mechanistic Similarities between Response Regulator Signaling Proteins and Haloacid Dehalogenase Phosphatases.
Biochemistry, 54, 2015
3RVN
DownloadVisualize
BU of 3rvn by Molmil
Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89Y
分子名称: BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein CheY, GLYCEROL, ...
著者Starbird, C.A, Immormino, R.M, Silversmith, R.E, Bourret, R.B.
登録日2011-05-06
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Probing Mechanistic Similarities between Response Regulator Signaling Proteins and Haloacid Dehalogenase Phosphatases.
Biochemistry, 54, 2015
3RVL
DownloadVisualize
BU of 3rvl by Molmil
Structure of the CheY-BeF3 Complex with substitutions at 59 and 89: N59D and E89R
分子名称: BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein CheY, GLYCEROL, ...
著者Starbird, C.A, Immormino, R.M, Silversmith, R.E, Bourret, R.B.
登録日2011-05-06
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Probing Mechanistic Similarities between Response Regulator Signaling Proteins and Haloacid Dehalogenase Phosphatases.
Biochemistry, 54, 2015
2AQ9
DownloadVisualize
BU of 2aq9 by Molmil
Structure of E. coli LpxA with a bound peptide that is competitive with acyl-ACP
分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
著者Williams, A.H, Immormino, R.M, Gewirth, D.T, Raetz, C.R.
登録日2005-08-17
公開日2006-06-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide.
Proc.Natl.Acad.Sci.Usa, 103, 2006
4HNY
DownloadVisualize
BU of 4hny by Molmil
Apo N-terminal acetyltransferase complex A
分子名称: GLYCEROL, N-terminal acetyltransferase A complex catalytic subunit ARD1, N-terminal acetyltransferase A complex subunit NAT1, ...
著者Neubauer, J.L, Immormino, R.M, Dollins, D.E, Endo-Streeter, S.T, Pemble IV, C.W, York, J.D.
登録日2012-10-21
公開日2014-03-26
実験手法X-RAY DIFFRACTION (2.249 Å)
主引用文献The Protein Complex NatA Binds Inositol Hexakisphosphate and Exhibits Conformational Flexibility
To be Published
4HNW
DownloadVisualize
BU of 4hnw by Molmil
The NatA Acetyltransferase Complex Bound To Inositol Hexakisphosphate
分子名称: INOSITOL HEXAKISPHOSPHATE, N-terminal acetyltransferase A complex catalytic subunit ARD1, N-terminal acetyltransferase A complex subunit NAT1, ...
著者Neubauer, J.L, Immormino, R.M, Dollins, D.E, Endo-Streeter, S.T, Pemble IV, C.W, York, J.D.
登録日2012-10-21
公開日2014-03-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献The Protein Complex NatA Binds Inositol Hexakisphosphate and Exhibits Conformational Flexibility
To be Published
4HNX
DownloadVisualize
BU of 4hnx by Molmil
The NatA Acetyltransferase Complex Bound To ppGpp
分子名称: GUANOSINE-5',3'-TETRAPHOSPHATE, N-terminal acetyltransferase A complex catalytic subunit ARD1, N-terminal acetyltransferase A complex subunit NAT1
著者Neubauer, J.L, Immormino, R.M, Dollins, D.E, Endo-Streeter, S.T, Pemble IV, C.W, York, J.D.
登録日2012-10-21
公開日2014-03-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.339 Å)
主引用文献The Protein Complex NatA Binds Inositol Hexakisphosphate and Exhibits Conformational Flexibility
To be Published
6D1X
DownloadVisualize
BU of 6d1x by Molmil
N-Domain Of Grp94, with the Charged Domain, In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine
分子名称: Endoplasmin, N-PROPYL CARBOXYAMIDO ADENOSINE, TETRAETHYLENE GLYCOL
著者Gewirth, D.T, Immormino, R.M.
登録日2018-04-12
公開日2018-05-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献NECA derivatives exploit the paralog-specific properties of the site 3 side pocket of Grp94, the endoplasmic reticulum Hsp90.
J.Biol.Chem., 294, 2019
2O1T
DownloadVisualize
BU of 2o1t by Molmil
Structure of Middle plus C-terminal domains (M+C) of GRP94
分子名称: Endoplasmin
著者Dollins, D.E, Warren, J.J, Immormino, R.M, Gewirth, D.T.
登録日2006-11-29
公開日2007-10-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Mol.Cell, 28, 2007
2O1U
DownloadVisualize
BU of 2o1u by Molmil
Structure of full length GRP94 with AMP-PNP bound
分子名称: Endoplasmin, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Dollins, D.E, Warren, J.J, Immormino, R.M, Gewirth, D.T.
登録日2006-11-29
公開日2007-10-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Mol.Cell, 28, 2007
2O1V
DownloadVisualize
BU of 2o1v by Molmil
Structure of full length GRP94 with ADP bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION
著者Dollins, D.E, Warren, J.J, Immormino, R.M, Gewirth, D.T.
登録日2006-11-29
公開日2007-10-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Mol.Cell, 28, 2007
2O1W
DownloadVisualize
BU of 2o1w by Molmil
Structure of N-terminal plus middle domains (N+M) of GRP94
分子名称: Endoplasmin
著者Dollins, D.E, Warren, J.J, Immormino, R.M, Gewirth, D.T.
登録日2006-11-29
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Mol.Cell, 28, 2007
1U0Z
DownloadVisualize
BU of 1u0z by Molmil
N-Domain Of Grp94 Lacking The Charged Domain In Complex With Radicicol
分子名称: Endoplasmin, PENTAETHYLENE GLYCOL, RADICICOL, ...
著者Gewirth, D.T, Immormino, R.M.
登録日2004-07-14
公開日2005-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献N-Domain Of Grp94 Lacking The Charged Domain In Complex With Radicicol
TO BE PUBLISHED
1YT0
DownloadVisualize
BU of 1yt0 by Molmil
Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL SOAKED WITH ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION, ...
著者Dollins, D.E, Immormino, R.M, Gewirth, D.T.
登録日2005-02-09
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
1YSZ
DownloadVisualize
BU of 1ysz by Molmil
Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL SOAKED WITH NECA
分子名称: Endoplasmin, N-ETHYL-5'-CARBOXAMIDO ADENOSINE, TETRAETHYLENE GLYCOL
著者Dollins, D.E, Immormino, R.M, Gewirth, D.T.
登録日2005-02-09
公開日2005-06-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
1YT1
DownloadVisualize
BU of 1yt1 by Molmil
Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL
分子名称: Endoplasmin, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL
著者Dollins, D.E, Immormino, R.M, Gewirth, D.T.
登録日2005-02-09
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
1YT2
DownloadVisualize
BU of 1yt2 by Molmil
Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N APO CRYSTAL
分子名称: Endoplasmin, TETRAETHYLENE GLYCOL
著者Dollins, D.E, Immormino, R.M, Gewirth, D.T.
登録日2005-02-09
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
3OO0
DownloadVisualize
BU of 3oo0 by Molmil
Structure of apo CheY A113P
分子名称: AMMONIUM ION, Chemotaxis protein CheY, GLYCEROL, ...
著者Pazy, Y, Collins, E.J, Guanga, G.P, Miller, P.J, Immormino, R.M, Silversmith, R.E, Bourret, R.B.
登録日2010-08-30
公開日2011-08-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Exploring the effect of an allosteric site on conformational coupling in CheY
To be Published

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon