8TH3
 
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6APD
 | | Crystal structure of RSV F bound by AM22 and the infant antibody ADI-19425 | | 分子名称: | AM22 Fab Heavy Chain,IGH@ protein, AM22 Fab Light Chain,Uncharacterized protein, Fusion glycoprotein F0,Envelope glycoprotein, ... | | 著者 | Wrapp, D, McLellan, J.S. | | 登録日 | 2017-08-17 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.
Immunity, 48, 2018
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6BLI
 | | RSV G peptide bound to Fab CB002.5 | | 分子名称: | CB002.5 Fab Heavy Chain, CB002.5 Fab Light Chain, Major surface glycoprotein G | | 著者 | Jones, H.G, McLellan, J.S, Langedijk, J.P. | | 登録日 | 2017-11-10 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
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6BLH
 | | RSV G central conserved region bound to Fab CB017.5 | | 分子名称: | 1,2-ETHANEDIOL, Fab CB017.5 heavy chain, Fab CB017.5 light chain, ... | | 著者 | Jones, H.G, McLellan, J.S, Langedijk, J.P. | | 登録日 | 2017-11-10 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
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7JQZ
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7JQY
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7JQX
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7LUC
 | | Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B | | 分子名称: | 01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ... | | 著者 | Wrapp, D, McLellan, J.S. | | 登録日 | 2021-02-22 | | 公開日 | 2021-04-21 | | 最終更新日 | 2021-04-28 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
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7LUD
 | | Crystal structure of Fab ADI-14442 | | 分子名称: | ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION | | 著者 | Rush, S.A, McLellan, J.S. | | 登録日 | 2021-02-22 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
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7KQD
 | | Prefusion RSV F Bound to RV521 | | 分子名称: | 1'-{[5-(aminomethyl)-1-(4,4,4-trifluorobutyl)-1H-benzimidazol-2-yl]methyl}-6'-fluorospiro[cyclopropane-1,3'-indol]-2'(1'H)-one, Fusion glycoprotein F0, SULFATE ION | | 著者 | McLellan, J.S. | | 登録日 | 2020-11-14 | | 公開日 | 2021-04-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion.
J.Med.Chem., 64, 2021
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