5JGI
 
 | | X-ray structure of neuropilin-1 b1 domain complexed with M45 compound | | 分子名称: | N-ALPHA-L-ACETYL-ARGININE, Neuropilin-1 | | 著者 | Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. | | 登録日 | 2016-04-20 | | 公開日 | 2017-05-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Architecture and hydration of the arginine-binding site of neuropilin-1.
FEBS J., 285, 2018
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5L73
 | | MAM domain of human neuropilin-1 | | 分子名称: | BICINE, CALCIUM ION, Neuropilin-1, ... | | 著者 | Yelland, T, Djordjevic, S. | | 登録日 | 2016-06-01 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Crystal Structure of the Neuropilin-1 MAM Domain: Completing the Neuropilin-1 Ectodomain Picture.
Structure, 24, 2016
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5DN2
 | | Human NRP2 b1 domain in complex with the peptide corresponding to the C-terminus of VEGF-A | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, GLYCEROL, Neuropilin-2, ... | | 著者 | Tsai, Y.C.I, Frankel, P, Fotinou, C, Rana, R, Zachary, I, Djordjevic, S. | | 登録日 | 2015-09-09 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket.
Febs J., 283, 2016
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5DQ0
 | | Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | | 著者 | Tsai, Y.I, Rana, R.R, Zachary, I, Djordjevic, S. | | 登録日 | 2015-09-14 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site
To Be Published
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1LW1
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6FMF
 | | Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure | | 分子名称: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1, trifluoroacetic acid | | 著者 | Yelland, T, Djordjevic, S, Selwood, D, Zachary, I, Frankel, P. | | 登録日 | 2018-01-31 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.811 Å) | | 主引用文献 | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
J. Med. Chem., 61, 2018
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6FMC
 | | Neuropilin1-b1 domain in complex with EG01377, 0.9 Angstrom structure | | 分子名称: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1 | | 著者 | Yelland, T, Djordjevic, S, Fotinou, K, Selwood, D, Zachary, I, Frankel, P. | | 登録日 | 2018-01-30 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | | 主引用文献 | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells.
J. Med. Chem., 61, 2018
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6TJT
 | | Neuropilin2-b1 domain in a complex with the C-terminal VEGFC peptide | | 分子名称: | 1,2-ETHANEDIOL, Neuropilin-2, SULFATE ION, ... | | 著者 | Eldrid, C, Yu, L, Yelland, T, Fotinou, C, Djordjevic, S. | | 登録日 | 2019-11-26 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | NRP2-b1 domain in a complex with the C-terminal VEGFC peptide
To Be Published
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6TKK
 | | Neuropilin 1-b1 domain in a complex with the C-terminal VEGFB186 peptide | | 分子名称: | 1,2-ETHANEDIOL, ACE-ARG-PRO-GLN-PRO-ARG, Neuropilin-1 | | 著者 | Eldrid, C, Yu, L, Yelland, T, Fotinou, C, Djordjevic, S. | | 登録日 | 2019-11-28 | | 公開日 | 2020-12-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | | 主引用文献 | Neuropilin 1-b1 domain in a complex with the C-terminal VEGFB186 peptide
To Be Published
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6TDB
 | | Neuropilin2-b1 domain in a complex with the C-terminal VEGFB167 peptide | | 分子名称: | 1,2-ETHANEDIOL, ACETYL GROUP, C-terminal VEGFB167 peptide, ... | | 著者 | Eldrid, C, Yu, L, Yelland, T, Fotinou, C, Djordjevic, S. | | 登録日 | 2019-11-08 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | NRP2-b1 domain in a complex with the C-terminal VEGFB167 peptide
To Be Published
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1EVV
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3ZXO
 | | CRYSTAL STRUCTURE OF THE MUTANT ATP-BINDING DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | | 分子名称: | ACETATE ION, GLYCEROL, REDOX SENSOR HISTIDINE KINASE RESPONSE REGULATOR DEVS, ... | | 著者 | Cho, H.Y, Cho, H.J, Kang, B.S. | | 登録日 | 2011-08-13 | | 公開日 | 2011-08-24 | | 最終更新日 | 2013-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Activation of ATP Binding for the Autophosphorylation of Doss, a Mycobacterium Tuberculosis Histidine Kinase Lacking an ATP-Lid Motif.
J.Biol.Chem., 288, 2013
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3ZXQ
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1CHD
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