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8D9I
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BU of 8d9i by Molmil
gRAMP non-matching PFS-with Mg
分子名称: RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*A)-3'), ...
著者Hu, C, Nam, K.H, Schuler, G, Ke, A.
登録日2022-06-09
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Craspase is a CRISPR RNA-guided, RNA-activated protease.
Science, 377, 2022
4Y1M
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BU of 4y1m by Molmil
An Escherichia coli yybP-ykoY Mn riboswitch in the Mn2+-free state
分子名称: E. coli yybP-ykoY riboswitch, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Price, I.R, Ke, A.
登録日2015-02-08
公開日2015-04-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mn(2+)-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches.
Mol.Cell, 57, 2015
4Y1I
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BU of 4y1i by Molmil
Lactococcus lactis yybP-ykoY Mn riboswitch bound to Mn2+
分子名称: BARIUM ION, GUANOSINE-5'-TRIPHOSPHATE, Lactococcus lactis yybP-ykoY riboswitch, ...
著者Price, I.R, Ke, A.
登録日2015-02-07
公開日2015-04-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Mn(2+)-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches.
Mol.Cell, 57, 2015
4Y1J
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BU of 4y1j by Molmil
Lactococcus lactis yybP-ykoY Mn riboswitch A41U binding site mutant in presence of Mn2+
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, STRONTIUM ION, ...
著者Price, I.R, Ke, A.
登録日2015-02-07
公開日2015-04-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Mn(2+)-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches.
Mol.Cell, 57, 2015
7LAW
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BU of 7law by Molmil
crystal structure of GITR complex with GITR-L
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18
著者Longenecker, K.L, Rogers, B, Bigelow, L, Judge, R.A, Alvarez, H.
登録日2021-01-07
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.752 Å)
主引用文献An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy.
Nat Cancer, 3, 2022
6QPA
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BU of 6qpa by Molmil
Halothiobacillus neapolitanus sulfur oxygenase reductase
分子名称: FE (III) ION, SULFATE ION, Sulfur oxygenase/reductase
著者Frazao, C, Klezin, A, Poell, U, Veith, A, Ruehl, P, Coelho, R.
登録日2019-02-13
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Multiple sulfane modifications in active-site cysteine thiols of two sulfur oxygenase reductases and analysis of substrate/product channels
To Be Published
9FAY
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BU of 9fay by Molmil
Gcase in complex with small molecule inhibitor 1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Tisi, D, Cleasby, A.
登録日2024-05-10
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of beta-Glucocerebrosidase.
J.Med.Chem., 2024
9FA3
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BU of 9fa3 by Molmil
Gcase in complex with small molecule inhibitor 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosomal acid glucosylceramidase, ...
著者Tisi, D, Cleasby, A.
登録日2024-05-10
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of beta-Glucocerebrosidase.
J.Med.Chem., 2024
9FAL
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BU of 9fal by Molmil
Gcase in complex with small molecule inhibitor 1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Tisi, D, Cleasby, A.
登録日2024-05-10
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of beta-Glucocerebrosidase.
J.Med.Chem., 2024
9FB2
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BU of 9fb2 by Molmil
Gcase in complex with small molecule inhibitor 1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Tisi, D, Cleasby, A.
登録日2024-05-11
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of beta-Glucocerebrosidase.
J.Med.Chem., 2024
9FA6
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BU of 9fa6 by Molmil
Gcase in complex with small molecule inhibitor 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosomal acid glucosylceramidase, ...
著者Tisi, D, Cleasby, A.
登録日2024-05-10
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of beta-Glucocerebrosidase.
J.Med.Chem., 2024
9FAD
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BU of 9fad by Molmil
Gcase in complex with small molecule inhibitor 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosomal acid glucosylceramidase, ...
著者Tisi, D, Cleasby, A.
登録日2024-05-10
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of beta-Glucocerebrosidase.
J.Med.Chem., 2024
9FAZ
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BU of 9faz by Molmil
Gcase in complex with small molecule inhibitor 1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Tisi, D, Cleasby, A.
登録日2024-05-10
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of beta-Glucocerebrosidase.
J.Med.Chem., 2024
9F9Z
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BU of 9f9z by Molmil
Gcase in complex with small molecule inhibitor 1
分子名称: (2~{S})-1-(2,6-dimethylphenoxy)propan-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosomal acid glucosylceramidase, ...
著者Tisi, D, Cleasby, A.
登録日2024-05-09
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.279 Å)
主引用文献Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of beta-Glucocerebrosidase.
J.Med.Chem., 2024
9FDI
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BU of 9fdi by Molmil
Gcase in complex with small molecule inhibitor 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(phenylmethyl)piperidine, ...
著者Tisi, D, Cleasby, A.
登録日2024-05-17
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of beta-Glucocerebrosidase.
J.Med.Chem., 2024
6C27
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BU of 6c27 by Molmil
SAM-III riboswitch ON-state
分子名称: COBALT HEXAMMINE(III), SAM-III riboswitch
著者Grigg, J.C, Price, I.R, Ke, A.
登録日2018-01-07
公開日2019-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.601 Å)
主引用文献Evidence for two-tiered conformation selection in the SAM-III riboswitch
To Be Published
4ES3
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BU of 4es3 by Molmil
Double-stranded Endonuclease Activity in B. halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein
分子名称: 1,2-ETHANEDIOL, BH0342 protein
著者Ke, A, Nam, K.H.
登録日2012-04-21
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.704 Å)
主引用文献Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein.
J. Biol. Chem., 287, 2012
4ES2
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BU of 4es2 by Molmil
Double-stranded Endonuclease Activity in B. halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein
分子名称: BH0342 protein
著者Ke, A, Nam, K.H.
登録日2012-04-21
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.299 Å)
主引用文献Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein.
J. Biol. Chem., 287, 2012
4ES1
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BU of 4es1 by Molmil
Double-stranded Endonuclease Activity in B. halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein
分子名称: BH0342 protein
著者Ke, A, Nam, K.H.
登録日2012-04-21
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein.
J. Biol. Chem., 287, 2012
4F3M
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BU of 4f3m by Molmil
Crystal structure of CRISPR-associated protein
分子名称: 1,2-ETHANEDIOL, BH0337 protein, SULFATE ION
著者Ke, A, Nam, K.H.
登録日2012-05-09
公開日2012-08-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System.
Structure, 20, 2012
4QQZ
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BU of 4qqz by Molmil
Crystal structure of T. fusca Cas3-AMPPNP
分子名称: CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
著者Ke, A, Huo, Y, Nam, K.H.
登録日2014-06-30
公開日2014-08-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4QQY
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BU of 4qqy by Molmil
Crystal structure of T. fusca Cas3-ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ...
著者Ke, A, Huo, Y, Nam, K.H.
登録日2014-06-30
公開日2014-08-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4QQX
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BU of 4qqx by Molmil
Crystal structure of T. fusca Cas3-ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ...
著者Ke, A, Huo, Y, Nam, K.H.
登録日2014-06-30
公開日2014-08-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4QQW
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BU of 4qqw by Molmil
Crystal structure of T. fusca Cas3
分子名称: CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
著者Ke, A, Huo, Y, Nam, K.H.
登録日2014-06-30
公開日2014-08-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.664 Å)
主引用文献Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4KQY
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BU of 4kqy by Molmil
Bacillus subtilis yitJ S box/SAM-I riboswitch
分子名称: MAGNESIUM ION, S-ADENOSYLMETHIONINE, YitJ S box/SAM-I riboswitch
著者Lu, C.
登録日2013-05-15
公開日2013-08-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献SAM recognition and conformational switching mechanism in the Bacillus subtilis yitJ S box/SAM-I riboswitch
J.Mol.Biol., 404, 2010

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件を2024-07-10に公開中

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