Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5THT
DownloadVisualize
BU of 5tht by Molmil
Crystal Structure of G303A HDAC8 in complex with M344
分子名称: 1,2-ETHANEDIOL, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, ...
著者Porter, N.J, Christianson, D.W.
登録日2016-09-30
公開日2016-12-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.407 Å)
主引用文献Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.
Biochemistry, 55, 2016
5THS
DownloadVisualize
BU of 5ths by Molmil
Crystal Structure of G302A HDAC8 in complex with M344
分子名称: 1,2-ETHANEDIOL, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, ...
著者Porter, N.J, Christianson, D.W.
登録日2016-09-30
公開日2016-12-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.
Biochemistry, 55, 2016
5THU
DownloadVisualize
BU of 5thu by Molmil
Crystal Structure of G304A HDAC8 in complex with M344
分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, POTASSIUM ION, ...
著者Porter, N.J, Christianson, D.W.
登録日2016-09-30
公開日2016-12-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.
Biochemistry, 55, 2016
5THV
DownloadVisualize
BU of 5thv by Molmil
Crystal Structure of G305A HDAC8 in complex with M344
分子名称: 1,2-ETHANEDIOL, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, ...
著者Porter, N.J, Christianson, D.W.
登録日2016-09-30
公開日2016-12-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.868 Å)
主引用文献Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.
Biochemistry, 55, 2016
2IES
DownloadVisualize
BU of 2ies by Molmil
Crystal Structure of Aquifex aeolicus LpxC Complexed with Pyrophosphate
分子名称: CHLORIDE ION, PALMITIC ACID, PYROPHOSPHATE 2-, ...
著者Gennadios, H.A, Christianson, D.W.
登録日2006-09-19
公開日2007-01-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Binding of Uridine 5-Diphosphate in the Basic Patch of the Zinc Metalloenzyme Deacetylase LpxC and Implications for Substrate Binding
Biochemistry, 45, 2006
2IMP
DownloadVisualize
BU of 2imp by Molmil
Crystal structure of lactaldehyde dehydrogenase from E. coli: the ternary complex with lactate (occupancy 0.5) and NADH. Crystals soaked with (L)-Lactate.
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, LACTIC ACID, Lactaldehyde dehydrogenase, ...
著者Di Costanzo, L, Gomez, G.A, Christianson, D.W.
登録日2006-10-04
公開日2007-02-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Lactaldehyde Dehydrogenase from Escherichia coli and Inferences Regarding Substrate and Cofactor Specificity.
J.Mol.Biol., 366, 2007
2ILU
DownloadVisualize
BU of 2ilu by Molmil
Crystal structure of lactaldehyde dehydrogenase from E. coli: the binary complex with NADPH
分子名称: Aldehyde dehydrogenase A, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
著者Di Costanzo, L, Gomez, G, Christianson, D.W.
登録日2006-10-03
公開日2007-05-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of lactaldehyde dehydrogenase from Escherichia coli and inferences regarding substrate and cofactor specificity.
J.Mol.Biol., 366, 2007
7CA2
DownloadVisualize
BU of 7ca2 by Molmil
ENGINEERING THE HYDROPHOBIC POCKET OF CARBONIC ANHYDRASE II
分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION
著者Nair, S.K, Christianson, D.W.
登録日1991-07-09
公開日1992-07-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Engineering the hydrophobic pocket of carbonic anhydrase II.
Biochemistry, 30, 1991
3CAA
DownloadVisualize
BU of 3caa by Molmil
CLEAVED ANTICHYMOTRYPSIN A347R
分子名称: ANTICHYMOTRYPSIN
著者Lukacs, C.M, Christianson, D.W.
登録日1997-08-18
公開日1998-02-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction.
Biochemistry, 37, 1998
5D1C
DownloadVisualize
BU of 5d1c by Molmil
Crystal structure of D233G-Y306F HDAC8 in complex with a tetrapeptide substrate
分子名称: GLYCEROL, HDAC8 Fluor de Lys tetrapeptide substrate, Histone deacetylase 8, ...
著者Decroos, C, Christianson, N.H, Gullett, L.E, Bowman, C.M, Christianson, K.E, Deardorff, M.A, Christianson, D.W.
登録日2015-08-04
公開日2015-10-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.422 Å)
主引用文献Biochemical and Structural Characterization of HDAC8 Mutants Associated with Cornelia de Lange Syndrome Spectrum Disorders.
Biochemistry, 54, 2015
8V0F
DownloadVisualize
BU of 8v0f by Molmil
Cryo-EM structure of the unliganded hexameric prenyltransferase in bifunctional copalyl diphosphate synthase from Penicillium fellutanum with an open conformation
分子名称: Copalyl diphosphate synthase
著者Gaynes, M.N, Christianson, D.W.
登録日2023-11-17
公開日2024-01-17
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structure of the prenyltransferase in bifunctional copalyl diphosphate synthase from Penicillium fellutanum reveals an open hexamer conformation.
J.Struct.Biol., 216, 2024
2ZNC
DownloadVisualize
BU of 2znc by Molmil
MURINE CARBONIC ANHYDRASE IV
分子名称: CARBONIC ANHYDRASE IV, ZINC ION
著者Stams, T, Chen, Y, Christianson, D.W.
登録日1998-02-10
公開日1999-03-23
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination.
Protein Sci., 7, 1998
1WVB
DownloadVisualize
BU of 1wvb by Molmil
Crystal structure of human arginase I: the mutant E256Q
分子名称: Arginase 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE
著者Di Costanzo, L, Guadalupe, S, Mora, A, Centeno, F, Christianson, D.W.
登録日2004-12-14
公開日2005-09-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human arginase I: the mutant E256Q
To be Published
8D7F
DownloadVisualize
BU of 8d7f by Molmil
FlvF from Aspergillus flavus in complex with Bis-Tris
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Terpene cyclase flvF
著者Tararina, M.A, Christianson, D.W.
登録日2022-06-07
公開日2022-09-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structure of the Repurposed Fungal Terpene Cyclase FlvF Implicated in the C-N Bond-Forming Reaction of Flavunoidine Biosynthesis.
Biochemistry, 61, 2022
8D9C
DownloadVisualize
BU of 8d9c by Molmil
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with fluorinated inhibitor 10
分子名称: 2,3,4,5,6-pentafluoro-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ...
著者Watson, P.R, Christianson, D.W.
登録日2022-06-09
公開日2022-09-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6.
Biochemistry, 61, 2022
8D98
DownloadVisualize
BU of 8d98 by Molmil
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with fluorinated inhibitor 5
分子名称: 3,5-difluoro-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ...
著者Watson, P.R, Christianson, D.W.
登録日2022-06-09
公開日2022-09-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6.
Biochemistry, 61, 2022
8D99
DownloadVisualize
BU of 8d99 by Molmil
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with fluorinated inhibitor 7
分子名称: 2,3,6-trifluoro-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ...
著者Watson, P.R, Christianson, D.W.
登録日2022-06-09
公開日2022-09-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6.
Biochemistry, 61, 2022
8D9B
DownloadVisualize
BU of 8d9b by Molmil
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with fluorinated inhibitor 9
分子名称: 2,3,5,6-tetrafluoro-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ...
著者Watson, P.R, Christianson, D.W.
登録日2022-06-09
公開日2022-09-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6.
Biochemistry, 61, 2022
8D9A
DownloadVisualize
BU of 8d9a by Molmil
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with fluorinated inhibitor 8
分子名称: 2,3,5-trifluoro-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ...
著者Watson, P.R, Christianson, D.W.
登録日2022-06-09
公開日2022-09-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6.
Biochemistry, 61, 2022
1URT
DownloadVisualize
BU of 1urt by Molmil
MURINE CARBONIC ANHYDRASE V
分子名称: CARBONIC ANHYDRASE V, ZINC ION
著者Boriack-Sjodin, P.A, Christianson, D.W.
登録日1996-07-03
公開日1997-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-based design of an intramolecular proton transfer site in murine carbonic anhydrase V.
Biochemistry, 35, 1996
1WVA
DownloadVisualize
BU of 1wva by Molmil
Crystal structure of human arginase I from twinned crystal
分子名称: Arginase 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE
著者Di Costanzo, L, Sabio, G, Mora, A, Rodriguez, P.C, Ochoa, A.C, Centeno, F, Christianson, D.W.
登録日2004-12-14
公開日2005-09-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response
Proc.Natl.Acad.Sci.Usa, 102, 2005
6AX9
DownloadVisualize
BU of 6ax9 by Molmil
F95N Epi-isozizaene synthase
分子名称: Epi-isozizaene synthase, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ...
著者Blank, P.N, Barrow, G.H, Christianson, D.W.
登録日2017-09-06
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.
Biochemistry, 56, 2017
6AXM
DownloadVisualize
BU of 6axm by Molmil
F95Y Epi-isozizaene synthase
分子名称: Epi-isozizaene synthase, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ...
著者Blank, P.N, Barrow, G.H, Christianson, D.W.
登録日2017-09-07
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.
Biochemistry, 56, 2017
6AXO
DownloadVisualize
BU of 6axo by Molmil
F96S Epi-isozizaene synthase
分子名称: Epi-isozizaene synthase
著者Blank, P.N, Barrow, G.H, Christianson, D.W.
登録日2017-09-07
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.
Biochemistry, 56, 2017
6AXN
DownloadVisualize
BU of 6axn by Molmil
F95C Epi-isozizaene synthase
分子名称: Epi-isozizaene synthase, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ...
著者Blank, P.N, Barrow, G.H, Christianson, D.W.
登録日2017-09-07
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.
Biochemistry, 56, 2017

238582

件を2025-07-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon