Search by PDB author

Crystal structure of human FPPS in complex with salicylic acid derivative 3a
分子名称:	2-(naphthalen-1-ylmethoxy)benzoic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
著者	Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日	2015-09-01
公開日	2015-09-30
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015

Crystal structure of human FPPS in complex with biaryl compound 5
分子名称:	4-(naphthalen-1-yl)-1H-indole-2-carboxylic acid, Farnesyl pyrophosphate synthase, PHOSPHATE ION
著者	Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日	2015-09-02
公開日	2015-09-30
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015

Crystal structure of human FPPS in complex with biaryl compound 8e
分子名称:	8-(naphthalen-1-yl)-6-(1H-pyrrol-2-yl)quinoline-2-carboxylic acid, Farnesyl pyrophosphate synthase
著者	Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日	2015-09-02
公開日	2015-10-07
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015

Crystal structure of human FPPS in complex with biaryl compound 6
分子名称:	1H,1'H-4,4'-biindole-2-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
著者	Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日	2015-09-02
公開日	2015-09-30
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding. Chemmedchem, 10, 2015