2KZZ
 
 | | KLENOW FRAGMENT WITH NORMAL SUBSTRATE AND ZINC ONLY | | 分子名称: | DNA (5'-D(*GP*CP*TP*T*AP*CP*G)-3'), PROTEIN (DNA POLYMERASE I), ZINC ION | | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | | 登録日 | 1998-07-07 | | 公開日 | 1999-12-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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2KZM
 | | KLENOW FRAGMENT WITH NORMAL SUBSTRATE AND ZINC AND MANGANESE | | 分子名称: | DNA (5'-D(*GP*CP*TP*TP*A*CP*GP*C)-3'), MANGANESE (II) ION, PROTEIN (DNA POLYMERASE I), ... | | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | | 登録日 | 1998-07-03 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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6B14
 | | Crystal structure of Spinach RNA aptamer in complex with Fab BL3-6S97N | | 分子名称: | Heavy chain of Fab BL3-6S97N, Light chain of Fab BL3-6S97N, MAGNESIUM ION, ... | | 著者 | DasGupta, S, Shelke, S.A, Piccirilli, J.A. | | 登録日 | 2017-09-16 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography.
Nucleic Acids Res., 46, 2018
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6B3K
 | | Crystal structure of mutant Spinach RNA aptamer in complex with Fab BL3-6 | | 分子名称: | Heavy chain of Fab BL3-6, Light chain of Fab BL3-6, MAGNESIUM ION, ... | | 著者 | DasGupta, S, Koirala, D, Shelke, S.A, Piccirilli, J.A. | | 登録日 | 2017-09-22 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography.
Nucleic Acids Res., 46, 2018
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6DB8
 | | Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer | | 分子名称: | 2-[(Z)-(3-methyl-1,3-benzoxazol-2(3H)-ylidene)methyl]-3-(3-sulfopropyl)-1,3-benzothiazol-3-ium, Fab-Heavy chain, Fab-Light chain, ... | | 著者 | Shao, Y, Shelke, S.A, Laski, A, Piccirilli, J.A. | | 登録日 | 2018-05-02 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.86541343 Å) | | 主引用文献 | Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif.
Nat Commun, 9, 2018
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6DB9
 | | Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer | | 分子名称: | Fab-Heavy-Chain, Fab-Light-Chain, MAGNESIUM ION, ... | | 著者 | Shao, Y, Shelke, S.A, Laski, A, Piccirilli, J.A. | | 登録日 | 2018-05-02 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.025 Å) | | 主引用文献 | Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif.
Nat Commun, 9, 2018
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7JRT
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7JRS
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7JRR
 | | Crystal structures of artificially designed homomeric RNA nanoarchitectures | | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, RNA (50-MER) | | 著者 | Liu, D, Shao, Y, Piccirilli, J.A, Weizmann, Y. | | 登録日 | 2020-08-12 | | 公開日 | 2021-09-08 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Structures of artificially designed discrete RNA nanoarchitectures at near-atomic resolution.
Sci Adv, 7, 2021
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4Q9Q
 | | Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab | | 分子名称: | (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | | 著者 | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | | 登録日 | 2014-05-01 | | 公開日 | 2014-06-18 | | 最終更新日 | 2017-07-26 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
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4Q9R
 | | Crystal structure of an RNA aptamer bound to trifluoroethyl-ligand analog in complex with Fab | | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | | 著者 | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | | 登録日 | 2014-05-01 | | 公開日 | 2014-06-18 | | 最終更新日 | 2017-07-26 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
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6R47
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3HHN
 | | Crystal structure of class I ligase ribozyme self-ligation product, in complex with U1A RBD | | 分子名称: | Class I ligase ribozyme, self-ligation product, MAGNESIUM ION, ... | | 著者 | Shechner, D.M, Grant, R.A, Bagby, S.C, Bartel, D.P. | | 登録日 | 2009-05-15 | | 公開日 | 2009-11-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.987 Å) | | 主引用文献 | Crystal structure of the catalytic core of an RNA-polymerase ribozyme.
Science, 326, 2009
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6MIH
 | | Crystal structure of host-guest complex with PC hachimoji DNA | | 分子名称: | DNA (5'-D(*CP*TP*TP*AP*(1WA)P*CP*(DB)P*T)-3'), DNA (5'-D(P*AP*(DS)P*GP*(1W5)P*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase | | 著者 | Georgiadis, M.M. | | 登録日 | 2018-09-19 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
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6MIG
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6MIK
 | | Crystal structure of host-guest complex with PP hachimoji DNA | | 分子名称: | DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase | | 著者 | Georgiadis, M.M. | | 登録日 | 2018-09-19 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
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3QHT
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7R6N
 | | Exon-free state of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic trimeric construct | | 分子名称: | Group I intron, MAGNESIUM ION | | 著者 | Thelot, F, Liu, D, Liao, M, Yin, P. | | 登録日 | 2021-06-22 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly.
Nat.Methods, 19, 2022
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7R6M
 | | Post-2S intermediate of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic dimeric construct | | 分子名称: | Group I intron, Ligated exon mimic of the Group I intron, MAGNESIUM ION | | 著者 | Thelot, F, Liu, D, Liao, M, Yin, P. | | 登録日 | 2021-06-22 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly.
Nat.Methods, 19, 2022
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7R6L
 | | 5 prime exon-free pre-2S intermediate of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic dimeric construct | | 分子名称: | Group I intron, 3 prime fragment plus 3 prime exon, 5 prime fragment, ... | | 著者 | Thelot, F, Liu, D, Liao, M, Yin, P. | | 登録日 | 2021-06-22 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly.
Nat.Methods, 19, 2022
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7MLX
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4ONO
 | | CD1c in complex with PM (phosphomycoketide) | | 分子名称: | (4R,8S,16S,20R)-4,8,12,16,20-pentamethylheptacosyl dihydrogen phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin/T-cell surface glycoprotein CD1c/T-cell surface glycoprotein CD1b chimeric protein, ... | | 著者 | Roy, S, Adams, E.J. | | 登録日 | 2014-01-28 | | 公開日 | 2014-10-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.705 Å) | | 主引用文献 | Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by alpha beta T cells.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4ONH
 | | Crystal Structure of DN6 TCR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | | 著者 | Roy, S, Adams, E.J. | | 登録日 | 2014-01-28 | | 公開日 | 2014-10-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.008 Å) | | 主引用文献 | Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by alpha beta T cells.
Proc.Natl.Acad.Sci.USA, 111, 2014
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