1VDT
| The crystal structure of the tetragonal form of hen egg white lysozyme at 1.7 angstroms resolution under basic conditions in space | 分子名称: | Lysozyme C | 著者 | Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Yamane, T, DeLucas, L.J, Hirose, M. | 登録日 | 2004-03-24 | 公開日 | 2004-04-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The crystal structure of the tetragonal form of hen egg white lysozyme at 1.7 angstroms resolution under basic conditions in space to be published
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1UHG
| Crystal Structure of S-Ovalbumin At 1.9 Angstrom Resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ovalbumin, ... | 著者 | Yamasaki, M, Takahashi, N, Hirose, M. | 登録日 | 2003-07-03 | 公開日 | 2003-07-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of S-ovalbumin as a Non-loop-inserted Thermostabilized Serpin Form J.Biol.Chem., 278, 2003
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5AVG
| The 0.95 angstrom structure of thaumatin crystallized in high-strength agarose hydrogel | 分子名称: | Thaumatin-1 | 著者 | Sugiyama, S, Shimizu, N, Maruyama, M, Sazaki, G, Hirose, M, Adachi, H, Takano, K, Murakami, S, Inoue, T, Mori, Y, Matsumura, H. | 登録日 | 2015-06-16 | 公開日 | 2015-07-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Growth of protein crystals in hydrogels prevents osmotic shock J.Am.Chem.Soc., 134, 2012
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1AIV
| APO OVOTRANSFERRIN | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OVOTRANSFERRIN | 著者 | Kurokawa, H, Dewan, J.C, Mikami, B, Sacchettini, J.C, Hirose, M. | 登録日 | 1997-04-28 | 公開日 | 1998-04-29 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of hen apo-ovotransferrin. Both lobes adopt an open conformation upon loss of iron J.Biol.Chem., 274, 1999
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3WR7
| Crystal Structure of Spermidine Acetyltransferase from Escherichia coli | 分子名称: | COENZYME A, SPERMIDINE, Spermidine N1-acetyltransferase | 著者 | Sugiyama, S, Ishikawa, S, Tomitori, S, Niiyama, M, Hirose, M, Miyazaki, Y, Higashi, K, Adachi, H, Takano, K, Murakami, S, Inoue, T, Mori, Y, Kashiwagi, K, Igarashi, K, Matsumura, H. | 登録日 | 2014-02-20 | 公開日 | 2015-09-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular mechanism underlying promiscuous polyamine recognition by spermidine acetyltransferase Int.J.Biochem.Cell Biol., 76, 2016
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3WVM
| The 0.88 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with stearic acid | 分子名称: | Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ... | 著者 | Sugiyama, S, Matsuoka, S, Mizohata, E, Matsuoka, D, Ishida, H, Hirose, M, Kakinouchi, K, Hara, T, Matsumura, H, Murakami, S, Inoue, T, Murata, M. | 登録日 | 2014-05-25 | 公開日 | 2015-01-28 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (0.88 Å) | 主引用文献 | Water-mediated recognition of simple alkyl chains by heart-type fatty-acid-binding protein. Angew.Chem.Int.Ed.Engl., 54, 2015
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1TFA
| OVOTRANSFERRIN, N-TERMINAL LOBE, APO FORM | 分子名称: | PROTEIN (OVOTRANSFERRIN), SULFATE ION | 著者 | Mizutani, K, Yamashita, H, Mikami, B, Hirose, M. | 登録日 | 1999-01-07 | 公開日 | 1999-01-13 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Alternative structural state of transferrin. The crystallographic analysis of iron-loaded but domain-opened ovotransferrin N-lobe. J.Biol.Chem., 274, 1999
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2ZQ3
| The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.6 angstroms resolution | 分子名称: | Lysozyme C, SODIUM ION | 著者 | Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Hirose, M. | 登録日 | 2008-08-03 | 公開日 | 2008-09-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution To be Published
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2ZQ4
| The crystal structure of the orthorhombic form of hen egg white lysozyme at 2.0 angstroms resolution | 分子名称: | Lysozyme C | 著者 | Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Yamane, T, Hirose, M. | 登録日 | 2008-08-03 | 公開日 | 2008-09-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution To be Published
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4FC0
| Crystal Structure of Human Kinase Domain of B-raf with a DFG-out Inhibitor | 分子名称: | 2-chloro-3-[(2-cyanopropan-2-yl)oxy]-N-{5-[{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}(methyl)amino]-2-fluorophenyl}benzamide, Serine/threonine-protein kinase B-raf | 著者 | Yano, J.K, Aertgeerts, K. | 登録日 | 2012-05-23 | 公開日 | 2014-01-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives. Bioorg.Med.Chem., 20, 2012
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8X3H
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4DBN
| Crystal Structure of the Kinase domain of Human B-raf with a [1,3]thiazolo[5,4-b]pyridine derivative | 分子名称: | 2-chloro-3-(1-cyanocyclopropyl)-N-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)-2-fluorophenyl]benzamide, Serine/threonine-protein kinase B-raf | 著者 | Yano, J.K, Aertgeerts, K. | 登録日 | 2012-01-16 | 公開日 | 2012-04-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds. J.Med.Chem., 55, 2012
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7W71
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4KSP
| Crystal Structure of Human B-raf bound to a DFG-out Inhibitor TAK-632 | 分子名称: | N-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide, Serine/threonine-protein kinase B-raf | 著者 | Yano, J.K, Masanori, O. | 登録日 | 2013-05-17 | 公開日 | 2013-07-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives. J.Med.Chem., 56, 2013
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4KSQ
| Crystal Structure of Human B-raf bound to a DFG-out Inhibitor 5B | 分子名称: | N-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide, Serine/threonine-protein kinase B-raf | 著者 | Yano, J.K, Masanori, O. | 登録日 | 2013-05-17 | 公開日 | 2013-07-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives. J.Med.Chem., 56, 2013
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1NNT
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2YZ1
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7W6Z
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7W6X
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7W6Y
| Crystal structure of Kangiella koreensis RseP orthologue in complex with batimastat in space group P1 | 分子名称: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, Anti sigma-E protein, RseA, ... | 著者 | Imaizumi, Y, Takanuki, K, Nogi, T. | 登録日 | 2021-12-02 | 公開日 | 2022-09-07 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP. Sci Adv, 8, 2022
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7W70
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7VG7
| Plexin B1 extracellular fragment in complex with lasso-grafted PB1m6A9 peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-B1, TRIETHYLENE GLYCOL, ... | 著者 | Sugano, N.N, Hirata, K, Yamashita, K, Yamamoto, M, Arimori, T, Takagi, J. | 登録日 | 2021-09-14 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function. Structure, 30, 2022
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7VF3
| Plexin B1 extracellular fragment in complex with lasso-grafted PB1m7 peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Plexin-B1, ... | 著者 | Sugano, N.N, Hirata, K, Yamashita, K, Yamamoto, M, Arimori, T, Takagi, J. | 登録日 | 2021-09-10 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function. Structure, 30, 2022
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5AVD
| The 0.86 angstrom structure of elastase crystallized in high-strength agarose hydrogel | 分子名称: | Chymotrypsin-like elastase family member 1, SULFATE ION | 著者 | Sugiyama, S, Shimizu, N, Maruyama, M, Sazaki, G, Adachi, H, Takano, K, Murakami, S, Inoue, T, Mori, Y, Matsumura, H. | 登録日 | 2015-06-15 | 公開日 | 2015-07-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (0.86 Å) | 主引用文献 | Growth of protein crystals in hydrogels prevents osmotic shock J.Am.Chem.Soc., 134, 2012
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3VNT
| Crystal Structure of the Kinase domain of Human VEGFR2 with a [1,3]thiazolo[5,4-b]pyridine derivative | 分子名称: | 1,2-ETHANEDIOL, 2-chloro-3-(1-cyanocyclopropyl)-N-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)-2-fluorophenyl]benzamide, Vascular endothelial growth factor receptor 2 | 著者 | Oki, H. | 登録日 | 2012-01-17 | 公開日 | 2012-04-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds J.Med.Chem., 55, 2012
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