6MUK
 
 | | 1.93 Angstrom Resolution Crystal Structure of Peptidase M23 from Neisseria gonorrhoeae. | | 分子名称: | Peptidase M23, ZINC ION | | 著者 | Minasov, G, Shuvalova, L, Pshenychnyi, S, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2018-10-23 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | 1.93 Angstrom Resolution Crystal Structure of Peptidase M23 from Neisseria gonorrhoeae.
To Be Published
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8JQ9
 | | Novel Anti-phage System | | 分子名称: | Endonuclease GajA | | 著者 | Li, J, Wang, Z, Wang, L. | | 登録日 | 2023-06-13 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
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6MUQ
 | | 1.67 Angstrom Resolution Crystal Structure of Murein-DD-endopeptidase from Yersinia enterocolitica. | | 分子名称: | ACETATE ION, Murein-DD-endopeptidase, SULFATE ION | | 著者 | Minasov, G, Shuvalova, L, Kiryukhina, O, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2018-10-23 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | 1.67 Angstrom Resolution Crystal Structure of Murein-DD-endopeptidase from Yersinia enterocolitica.
To Be Published
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1JNY
 | | Crystal structure of Sulfolobus solfataricus elongation factor 1 alpha in complex with GDP | | 分子名称: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Vitagliano, L, Masullo, M, Sica, F, Zagari, A, Bocchini, V. | | 登録日 | 2001-07-26 | | 公開日 | 2002-01-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with GDP reveals novel features in nucleotide binding and exchange.
EMBO J., 20, 2001
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3EZR
 | | CDK-2 with indazole inhibitor 17 bound at its active site | | 分子名称: | 3-methoxy-4-{3-[4-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2 | | 著者 | Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. | | 登録日 | 2008-10-23 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor
Bioorg.Med.Chem.Lett., 19, 2009
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6JHQ
 | | The cryo-EM structure of HAV bound to a neutralizing antibody-F4 | | 分子名称: | FAB Heavy Chain, FAB Light Chain, VP1, ... | | 著者 | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | | 登録日 | 2019-02-18 | | 公開日 | 2020-03-18 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Plos Biol., 17, 2019
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6JHT
 | | The cryo-EM structure of HAV bound to a neutralizing antibody-F9 | | 分子名称: | FAB Heavy Chain, FAB Light Chain, VP1, ... | | 著者 | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | | 登録日 | 2019-02-19 | | 公開日 | 2020-03-18 | | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | | 主引用文献 | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Plos Biol., 17, 2019
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8JQC
 | | Novel Anti-phage System | | 分子名称: | Endonuclease GajA, Gabija protein GajB | | 著者 | Li, J, Wang, Z, Wang, L. | | 登録日 | 2023-06-13 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
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1JTP
 | | Degenerate interfaces in antigen-antibody complexes | | 分子名称: | FORMIC ACID, LYSOZYME C, SODIUM ION, ... | | 著者 | Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L. | | 登録日 | 2001-08-21 | | 公開日 | 2001-12-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Degenerate interfaces in antigen-antibody complexes.
J.Mol.Biol., 313, 2001
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8JQB
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6N1B
 | | Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii in complex with blood group B trisaccharide | | 分子名称: | CALCIUM ION, Carbohydrate-binding protein, GLYCEROL, ... | | 著者 | Sim, L, Rahfeld, P, Withers, S.G. | | 登録日 | 2018-11-08 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | An enzymatic pathway in the human gut microbiome that converts A to universal O type blood.
Nat Microbiol, 4, 2019
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6N31
 | | WD repeats of human WDR12 | | 分子名称: | Ribosome biogenesis protein WDR12, UNKNOWN ATOM OR ION | | 著者 | Halabelian, L, Zeng, H, Tempel, W, Li, Y, Seitova, A, Hutchinson, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2018-11-14 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | WD repeats of human WDR12
To Be Published
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6JFL
 | | Nucleotide-free Mitofusin2 (MFN2) | | 分子名称: | CALCIUM ION, GLYCEROL, Mitofusin-2,cDNA FLJ57997, ... | | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | | 登録日 | 2019-02-10 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
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6MJ2
 | | Human TRPM2 ion channel in a calcium- and ADPR-bound state | | 分子名称: | CALCIUM ION, Transient receptor potential cation channel subfamily M member 2 | | 著者 | Wang, L, Fu, T.M, Xia, S, Wu, H. | | 登録日 | 2018-09-20 | | 公開日 | 2018-12-12 | | 最終更新日 | 2019-01-02 | | 実験手法 | ELECTRON MICROSCOPY (6.36 Å) | | 主引用文献 | Structures and gating mechanism of human TRPM2.
Science, 362, 2018
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1PCO
 | | SOLUTION STRUCTURE OF PORCINE PANCREATIC PROCOLIPASE AS DETERMINED FROM 1H HOMONUCLEAR TWO-AND THREE-DIMENSIONAL NMR | | 分子名称: | HYDROXIDE ION, PORCINE PANCREATIC PROCOLIPASE B | | 著者 | Breg, J.N, Sarda, L, Cozzone, P.J, Rugani, N, Boelens, R, Kaptein, R. | | 登録日 | 1994-06-08 | | 公開日 | 1994-12-20 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of porcine pancreatic procolipase as determined from 1H homonuclear two-dimensional and three-dimensional NMR.
Eur.J.Biochem., 227, 1995
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6MYY
 | | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ... | | 著者 | Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D. | | 登録日 | 2018-11-02 | | 公開日 | 2018-11-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
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6N1A
 | | Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii | | 分子名称: | CALCIUM ION, Carbohydrate-binding protein, GLYCEROL, ... | | 著者 | Sim, L, Rahfeld, P, Withers, S.G. | | 登録日 | 2018-11-08 | | 公開日 | 2019-06-12 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | An enzymatic pathway in the human gut microbiome that converts A to universal O type blood.
Nat Microbiol, 4, 2019
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3FHW
 | | Crystal structure of the protein priB from Bordetella parapertussis. Northeast Structural Genomics Consortium target BpR162. | | 分子名称: | DI(HYDROXYETHYL)ETHER, Primosomal replication protein n, SODIUM ION | | 著者 | Kuzin, A.P, Neely, H, Seetharaman, J, Forouhar, F, Wang, D, Mao, L, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2008-12-10 | | 公開日 | 2008-12-30 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the protein priB from Bordetella parapertussis. Northeast Structural Genomics Consortium target BpR162.
To be Published
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6JFM
 | | Mitofusin2 (MFN2)_T111D | | 分子名称: | ACETATE ION, CALCIUM ION, Mitofusin-2,Mitofusin-2 | | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | | 登録日 | 2019-02-10 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
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6N8S
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2IAN
 | | Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR | | 分子名称: | 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ... | | 著者 | Deng, L, Langley, R.J, Mariuzza, R.A. | | 登録日 | 2006-09-08 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
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6MIW
 | | WWE domain of human HUWE1 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, E3 ubiquitin-protein ligase HUWE1, UNKNOWN ATOM OR ION | | 著者 | Halabelian, L, Loppnau, P, Tempel, W, Wong, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2018-09-20 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | WWE domain of human HUWE1
To Be Published
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6MGI
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3F5X
 | | CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site | | 分子名称: | 4-{3-[7-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl}aniline, Cell division protein kinase 2, Cyclin-A2, ... | | 著者 | Kiefer, J.R, Day, J.E, Caspers, N.L, Mathis, K.J, Kretzmer, K.K, Weinberg, R.A, Reitz, B.A, Stegeman, R.A, Trujillo, J.I, Huang, W, Thorarensen, A, Xing, L, Wrightstone, A, Christine, L, Compton, R, Li, X. | | 登録日 | 2008-11-04 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-zeta inhibitor.
Bioorg.Med.Chem.Lett., 19, 2009
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6MHW
 | | Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1) | | 分子名称: | Transient receptor potential cation channel subfamily V member 3 | | 著者 | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | | 登録日 | 2018-09-18 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
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