5GPK
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![BU of 5gpk by Molmil](/molmil-images/mine/5gpk) | Crystal structure of Ccp1 mutant | 分子名称: | Putative nucleosome assembly protein C36B7.08c | 著者 | Yin, F, Gao, F, Chen, Y. | 登録日 | 2016-08-03 | 公開日 | 2016-11-30 | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | 主引用文献 | Ccp1 Homodimer Mediates Chromatin Integrity by Antagonizing CENP-A Loading Mol.Cell, 64, 2016
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8G4U
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6JG5
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![BU of 6jg5 by Molmil](/molmil-images/mine/6jg5) | Crystal structure of AimR | 分子名称: | AimR transcriptional regulator | 著者 | Guan, Z.Y, Pei, K, Zou, T.T. | 登録日 | 2019-02-13 | 公開日 | 2019-07-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.221 Å) | 主引用文献 | Structural insights into DNA recognition by AimR of the arbitrium communication system in the SPbeta phage. Cell Discov, 5, 2019
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8WUL
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![BU of 8wul by Molmil](/molmil-images/mine/8wul) | Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) | 分子名称: | Beta-2-microglobulin, KRAS-G12V nonamer peptide, MHC class I antigen, ... | 著者 | Zhang, M.Y, Luo, L.J, Xu, W, Guan, F.H, Wang, X.Y, Zhu, P, Zhang, J.H, Zhou, X.Y, Wang, F, Ye, S. | 登録日 | 2023-10-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. Commun Biol, 7, 2024
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3NGQ
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![BU of 3ngq by Molmil](/molmil-images/mine/3ngq) | Crystal structure of the human CNOT6L nuclease domain | 分子名称: | 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, CCR4-NOT transcription complex subunit 6-like, MAGNESIUM ION | 著者 | Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z. | 登録日 | 2010-06-13 | 公開日 | 2010-07-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. Embo J., 2010
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8WTE
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![BU of 8wte by Molmil](/molmil-images/mine/8wte) | Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) | 分子名称: | Beta-2-microglobulin, KRAS-G12V nonamer peptide, MHC class I antigen (Fragment), ... | 著者 | Zhang, M.Y, Luo, L.J, Xu, W, Guan, F.H, Wang, X.Y, Zhu, P, Zhang, J.H, Zhou, X.Y, Wang, F, Ye, S. | 登録日 | 2023-10-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. Commun Biol, 7, 2024
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6X7V
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8FZ6
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![BU of 8fz6 by Molmil](/molmil-images/mine/8fz6) | The human PI31 complexed with bovine 20S proteasome | 分子名称: | Proteasome inhibitor PI31 subunit, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | 著者 | Hsu, H.-C, Li, H. | 登録日 | 2023-01-27 | 公開日 | 2023-07-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | Eta igh-resolution structure of mammalian PI31-20S proteasome complex reveals mechanism of proteasome inhibition. J.Biol.Chem., 299, 2023
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8FZ5
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![BU of 8fz5 by Molmil](/molmil-images/mine/8fz5) | The PI31-free Bovine 20S proteasome | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | 著者 | Hsu, H.-C, Li, H. | 登録日 | 2023-01-27 | 公開日 | 2023-07-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.23 Å) | 主引用文献 | Eta igh-resolution structure of mammalian PI31-20S proteasome complex reveals mechanism of proteasome inhibition. J.Biol.Chem., 299, 2023
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7C23
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![BU of 7c23 by Molmil](/molmil-images/mine/7c23) | Crystal structure of CrmE10, a SGNH-hydrolase family esterase | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | 著者 | Li, Z, Li, J. | 登録日 | 2020-05-07 | 公開日 | 2020-05-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases. Biotechnol Biofuels, 13, 2020
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7BR8
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![BU of 7br8 by Molmil](/molmil-images/mine/7br8) | Epstein-Barr virus, C5 penton vertex, CATC absent. | 分子名称: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | 著者 | Li, Z, Yu, X. | 登録日 | 2020-03-26 | 公開日 | 2020-09-30 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | CryoEM structure of the tegumented capsid of Epstein-Barr virus. Cell Res., 30, 2020
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3NGN
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![BU of 3ngn by Molmil](/molmil-images/mine/3ngn) | Crystal structure of the human CNOT6L nuclease domain in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, CCR4-NOT transcription complex subunit 6-like | 著者 | Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z. | 登録日 | 2010-06-12 | 公開日 | 2010-07-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. Embo J., 2010
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8IM7
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![BU of 8im7 by Molmil](/molmil-images/mine/8im7) | Human gamma-secretase treated with ganglioside GM1 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhou, R, Yang, G, Shi, Y. | 登録日 | 2023-03-06 | 公開日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Preferential Regulation of Gamma-Secretase-Mediated Cleavage of APP by Ganglioside GM1 Reveals a Potential Therapeutic Target for Alzheimer's Disease. Adv Sci, 10, 2023
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6BS2
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![BU of 6bs2 by Molmil](/molmil-images/mine/6bs2) | Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 8b | 分子名称: | 1-(3,6-dimethyl[1,2]oxazolo[5,4-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Kumar, G, Wang, Y, Li, W, White, S.W. | 登録日 | 2017-12-01 | 公開日 | 2018-06-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy. J. Med. Chem., 61, 2018
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7BSI
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6XBY
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![BU of 6xby by Molmil](/molmil-images/mine/6xby) | Cryo-EM structure of V-ATPase from bovine brain, state 2 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Wang, R, Li, X. | 登録日 | 2020-06-07 | 公開日 | 2020-08-19 | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | 主引用文献 | Cryo-EM structures of intact V-ATPase from bovine brain. Nat Commun, 11, 2020
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7BQT
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6BRY
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![BU of 6bry by Molmil](/molmil-images/mine/6bry) | Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 6a | 分子名称: | 1-(2-chlorofuro[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Kumar, G, Wang, Y, Li, W, White, S.W. | 登録日 | 2017-12-01 | 公開日 | 2018-06-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy. J. Med. Chem., 61, 2018
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6JG9
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5VZ4
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![BU of 5vz4 by Molmil](/molmil-images/mine/5vz4) | Receptor-growth factor crystal structure at 2.20 Angstrom resolution | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, GDNF family receptor alpha-like, ... | 著者 | Lakshminarasimhan, D, White, A, Suto, R.K. | 登録日 | 2017-05-26 | 公開日 | 2017-09-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15. Nature, 550, 2017
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5W0T
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7BQX
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![BU of 7bqx by Molmil](/molmil-images/mine/7bqx) | Epstein-Barr virus, C5 portal vertex | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Li, Z, Yu, X. | 登録日 | 2020-03-25 | 公開日 | 2020-09-30 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | CryoEM structure of the tegumented capsid of Epstein-Barr virus. Cell Res., 30, 2020
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8X4Z
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![BU of 8x4z by Molmil](/molmil-images/mine/8x4z) | BA.2.86 Spike Trimer with ins483V mutation (3 RBD down) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yue, C, Liu, P. | 登録日 | 2023-11-16 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024
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8X56
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![BU of 8x56 by Molmil](/molmil-images/mine/8x56) | BA.2.86 Spike Trimer with T356K mutation (1 RBD up) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Yue, C, Liu, P. | 登録日 | 2023-11-16 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024
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8WHZ
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![BU of 8whz by Molmil](/molmil-images/mine/8whz) | BA.2.86 RBD in complex with hACE2 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ... | 著者 | Yue, C, Liu, P. | 登録日 | 2023-09-23 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity Natl Sci Rev, 2024
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