3VHA
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![BU of 3vha by Molmil](/molmil-images/mine/3vha) | Hsp90 alpha N-terminal domain in complex with a macrocyclic inhibitor | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 22-methyl-13,18-dioxa-7-thia-3,5-diazatetracyclo[17.3.1.1~2,6~.1~8,12~]pentacosa-1(23),2(25),3,5,8(24),9,11,19,21-nonaen-4-amine, Heat shock protein HSP 90-alpha | 著者 | Fukami, T.A, Ono, N. | 登録日 | 2011-08-24 | 公開日 | 2012-07-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors Bioorg.Med.Chem.Lett., 22, 2012
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2CZN
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![BU of 2czn by Molmil](/molmil-images/mine/2czn) | Solution structure of the chitin-binding domain of hyperthermophilic chitinase from pyrococcus furiosus | 分子名称: | chitinase | 著者 | Uegaki, T, Ikegami, T, Nakamura, T, Hagihara, Y, Mine, S, Inoue, T, Matsumura, H, Ataka, M, Ishikawa, K. | 登録日 | 2005-07-13 | 公開日 | 2006-07-18 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Tertiary structure and carbohydrate recognition by the chitin-binding domain of a hyperthermophilic chitinase from Pyrococcus furiosus. J.Mol.Biol., 381, 2008
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3VHC
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![BU of 3vhc by Molmil](/molmil-images/mine/3vhc) | Hsp90 alpha N-terminal domain in complex with a macrocyclic inhibitor | 分子名称: | 4-amino-20,22-dimethyl-13-oxa-7-thia-3,5,17-triazatetracyclo[17.3.1.1~2,6~.1~8,12~]pentacosa-1(23),2(25),3,5,8(24),9,11,19,21-nonaen-18-one, Heat shock protein HSP 90-alpha, MAGNESIUM ION | 著者 | Fukami, T.A, Ono, N. | 登録日 | 2011-08-24 | 公開日 | 2012-07-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors Bioorg.Med.Chem.Lett., 22, 2012
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3VUC
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![BU of 3vuc by Molmil](/molmil-images/mine/3vuc) | Human renin in complex with compound 5 | 分子名称: | (2R,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-2-ethyl-4-hydroxy-N-[(1R,2S,3S,5S,7S)-5-hydroxytricyclo[3.3.1.1~3,7~]dec-2-yl]hexanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin | 著者 | Takahashi, M, Matsui, Y, Hanzawa, H. | 登録日 | 2012-06-26 | 公開日 | 2013-05-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor. Acs Med.Chem.Lett., 3, 2012
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3VHD
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![BU of 3vhd by Molmil](/molmil-images/mine/3vhd) | Hsp90 alpha N-terminal domain in complex with a macrocyclic inhibitor, CH5164840 | 分子名称: | 4-amino-18,20-dimethyl-7-thia-3,5,11,15-tetraazatricyclo[15.3.1.1(2,6)]docosa-1(20),2,4,6(22),17(21),18-hexaene-10,16-dione, Heat shock protein HSP 90-alpha | 著者 | Fukami, T.A, Ono, N. | 登録日 | 2011-08-24 | 公開日 | 2012-07-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors Bioorg.Med.Chem.Lett., 22, 2012
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5X2V
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![BU of 5x2v by Molmil](/molmil-images/mine/5x2v) | |
5X2Y
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![BU of 5x2y by Molmil](/molmil-images/mine/5x2y) | |
5X2W
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![BU of 5x2w by Molmil](/molmil-images/mine/5x2w) | |
5X2Z
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![BU of 5x2z by Molmil](/molmil-images/mine/5x2z) | |
6SDG
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![BU of 6sdg by Molmil](/molmil-images/mine/6sdg) | |
5X30
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![BU of 5x30 by Molmil](/molmil-images/mine/5x30) | Crystal structure of Pseudomonas putida methionine gamma-lyase C116H mutant with L-homocysteine intermediates. | 分子名称: | (2E)-2-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}but-2-enoic acid, (2~{S})-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-4-sulfanyl-butanoic acid, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, ... | 著者 | Shiba, T, Sato, D, Harada, S. | 登録日 | 2017-02-02 | 公開日 | 2017-04-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and mechanistic insights into homocysteine degradation by a mutant of methionine gamma-lyase based on substrate-assisted catalysis Protein Sci., 26, 2017
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1IYL
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![BU of 1iyl by Molmil](/molmil-images/mine/1iyl) | Crystal Structure of Candida albicans N-myristoyltransferase with Non-peptidic Inhibitor | 分子名称: | (1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRIDIN-3-YLMETHYL)-AMINO]-PROPOXY}-BENZOFURAN-2-YL)-METHANONE, Myristoyl-CoA:Protein N-Myristoyltransferase | 著者 | Sogabe, S, Fukami, T.A, Morikami, K, Shiratori, Y, Aoki, Y, D'Arcy, A, Winkler, F.K, Banner, D.W, Ohtsuka, T. | 登録日 | 2002-08-29 | 公開日 | 2002-12-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal Structures of Candida albicans N-Myristoyltransferase with Two Distinct Inhibitors CHEM.BIOL., 9, 2002
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3WH5
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![BU of 3wh5 by Molmil](/molmil-images/mine/3wh5) | Crystal structure of GH1 beta-glucosidase Td2F2 | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, SODIUM ION, ... | 著者 | Jo, T, Fushinobu, S, Uchiyama, T, Yaoi, K. | 登録日 | 2013-08-21 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure and identification of a key amino acid for glucose tolerance, substrate specificity, and transglycosylation activity of metagenomic beta-glucosidase Td2F2. Febs J., 283, 2016
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4HL8
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![BU of 4hl8 by Molmil](/molmil-images/mine/4hl8) | Re-refinement of the vault ribonucleoprotein particle | 分子名称: | Major vault protein | 著者 | Casanas, A, Querol-Audi, J, Guerra, P, Pous, J, Tanaka, H, Tsukihara, T, Verdaguer, V, Fita, I. | 登録日 | 2012-10-16 | 公開日 | 2013-06-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | New features of vault architecture and dynamics revealed by novel refinement using the deformable elastic network approach. Acta Crystallogr.,Sect.D, 69, 2013
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3WH6
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![BU of 3wh6 by Molmil](/molmil-images/mine/3wh6) | Crystal structure of GH1 beta-glucosidase Td2F2 glucose complex | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SODIUM ION, alpha-D-glucopyranose, ... | 著者 | Jo, T, Fushinobu, S, Uchiyama, T, Yaoi, K. | 登録日 | 2013-08-21 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure and identification of a key amino acid for glucose tolerance, substrate specificity, and transglycosylation activity of metagenomic beta-glucosidase Td2F2. Febs J., 283, 2016
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3WH7
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![BU of 3wh7 by Molmil](/molmil-images/mine/3wh7) | Crystal structure of GH1 beta-glucosidase Td2F2 L-fucose complex | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SODIUM ION, beta-D-fucopyranose, ... | 著者 | Jo, T, Fushinobu, S, Uchiyama, T, Yaoi, K. | 登録日 | 2013-08-21 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Crystal structure and identification of a key amino acid for glucose tolerance, substrate specificity, and transglycosylation activity of metagenomic beta-glucosidase Td2F2. Febs J., 283, 2016
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3WH8
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![BU of 3wh8 by Molmil](/molmil-images/mine/3wh8) | Crystal structure of GH1 beta-glucosidase Td2F2 isofagomine complex | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, GLYCEROL, ... | 著者 | Jo, T, Fushinobu, S, Uchiyama, T, Yaoi, K. | 登録日 | 2013-08-21 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure and identification of a key amino acid for glucose tolerance, substrate specificity, and transglycosylation activity of metagenomic beta-glucosidase Td2F2. Febs J., 283, 2016
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2ZZU
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![BU of 2zzu by Molmil](/molmil-images/mine/2zzu) | Human Factor VIIA-Tissue Factor Complexed with ethylsulfonamide-D-5-(3-carboxybenzyloxy)-Trp-Gln-p-aminobenzamidine | 分子名称: | 3-[[3-[(2R)-3-[[(2S)-5-amino-1-[(4-carbamimidoylphenyl)methylamino]-1,5-dioxo-pentan-2-yl]amino]-2-(ethylsulfonylamino)-3-oxo-propyl]-1H-indol-5-yl]oxymethyl]benzoic acid, CALCIUM ION, Factor VII heavy chain, ... | 著者 | Kadono, S, Sakamoto, A, Kikuchi, Y, Oh-Eda, M, Yabuta, N, Koga, T, Hattori, K, Shiraishi, T, Haramura, M, Sato, H, Ohta, M, Kozono, T. | 登録日 | 2009-02-25 | 公開日 | 2009-03-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Design and synthesis of peptidomimetic factor VIIa inhibitors Chem.Pharm.Bull., 58, 2010
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4U8P
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![BU of 4u8p by Molmil](/molmil-images/mine/4u8p) | Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant Y317A complexed with UDP | 分子名称: | 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | 著者 | Qureshi, I.A, Chaudhary, R, Tanner, J.J. | 登録日 | 2014-08-03 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
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4U8K
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![BU of 4u8k by Molmil](/molmil-images/mine/4u8k) | Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant Q107A | 分子名称: | 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | 著者 | Qureshi, I.A, Chaudhary, R, Tanner, J.J. | 登録日 | 2014-08-03 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
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4U8M
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![BU of 4u8m by Molmil](/molmil-images/mine/4u8m) | Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant Y317A | 分子名称: | 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | 著者 | Qureshi, I.A, Chaudhary, R, Tanner, J.J. | 登録日 | 2014-08-03 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
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4U8N
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![BU of 4u8n by Molmil](/molmil-images/mine/4u8n) | Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant F66A complexed with UDP | 分子名称: | 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | 著者 | Qureshi, I.A, Chaudhary, R, Tanner, J.J. | 登録日 | 2014-08-03 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
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4U8L
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![BU of 4u8l by Molmil](/molmil-images/mine/4u8l) | Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant N207A | 分子名称: | 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | 著者 | Qureshi, I.A, Chaudhary, R, Tanner, J.J. | 登録日 | 2014-08-03 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
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4U8J
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![BU of 4u8j by Molmil](/molmil-images/mine/4u8j) | Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant Y104A | 分子名称: | 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | 著者 | Qureshi, I.A, Chaudhary, R, Tanner, J.J. | 登録日 | 2014-08-03 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
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4U8I
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![BU of 4u8i by Molmil](/molmil-images/mine/4u8i) | Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant F66A | 分子名称: | 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | 著者 | Qureshi, I.A, Chaudhary, R, Tanner, J.J. | 登録日 | 2014-08-03 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
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