3E2Y
 
 | | Crystal structure of mouse kynurenine aminotransferase III in complex with glutamine | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLUTAMINE, GLYCEROL, ... | | 著者 | Han, Q, Robinson, R, Cai, T, Tagle, D.A, Li, J. | | 登録日 | 2008-08-06 | | 公開日 | 2008-12-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Correction for Han et al., "Biochemical and Structural Properties of Mouse Kynurenine Aminotransferase III".
Mol. Cell. Biol., 38, 2018
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6BWD
 | | 3.7 angstrom cryoEM structure of truncated mouse TRPM7 | | 分子名称: | CHOLESTEROL HEMISUCCINATE, MAGNESIUM ION, Transient receptor potential cation channel subfamily M member 7 | | 著者 | Zhang, J, Li, Z, Duan, J, Li, J, Hulse, R.E, Santa-Cruz, A, Abiria, S.A, Krapivinsky, G, Clapham, D.E. | | 登録日 | 2017-12-14 | | 公開日 | 2018-08-15 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3E2Z
 | | Crystal structure of mouse kynurenine aminotransferase III in complex with kynurenine | | 分子名称: | (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, GLYCEROL, ... | | 著者 | Han, Q, Robinson, R, Cai, T, Tagle, D.A, Li, J. | | 登録日 | 2008-08-06 | | 公開日 | 2008-12-30 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Correction for Han et al., "Biochemical and Structural Properties of Mouse Kynurenine Aminotransferase III".
Mol. Cell. Biol., 38, 2018
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6BWI
 | | 3.7 angstrom cryoEM structure of full length human TRPM4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... | | 著者 | Zhang, J, Li, Z, Duan, J, Li, J, Clapham, D.E. | | 登録日 | 2017-12-15 | | 公開日 | 2018-12-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure of full-length human TRPM4.
Proc.Natl.Acad.Sci.USA, 115, 2018
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3E2F
 | | Crystal structure of mouse kynurenine aminotransferase III, PLP-bound form | | 分子名称: | GLYCEROL, Kynurenine-oxoglutarate transaminase 3 | | 著者 | Han, Q, Robinson, R, Cai, T, Tagle, D.A, Li, J. | | 登録日 | 2008-08-05 | | 公開日 | 2008-12-30 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Correction for Han et al., "Biochemical and Structural Properties of Mouse Kynurenine Aminotransferase III".
Mol. Cell. Biol., 38, 2018
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5DQU
 | | Crystal Structure of Cas-DNA-10 complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*TP*TP*TP*T)-3'), ... | | 著者 | Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y. | | 登録日 | 2015-09-15 | | 公開日 | 2015-11-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
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5DQZ
 | | Crystal Structure of Cas-DNA-PAM complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (36-MER), ... | | 著者 | Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y. | | 登録日 | 2015-09-15 | | 公開日 | 2015-11-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
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6KUZ
 | | E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSL01 | | 分子名称: | 3-(1,3-benzothiazol-2-yl)-2-[[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]methoxy]-5-methyl-benzaldehyde, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | | 著者 | Chen, X, Hu, Y.L, Li, X.K, Guo, Y, Li, J. | | 登録日 | 2019-09-03 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | | 主引用文献 | First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated beta-galactosidase.
Chem Sci, 11, 2020
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8HUR
 | | Crystal structure of SARS-Cov-2 main protease in complex with S217622 | | 分子名称: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | | 著者 | Zhou, X.L, Zhang, J, Li, J. | | 登録日 | 2022-12-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
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8HUS
 | | Crystal structure of SARS main protease in complex with S217622 | | 分子名称: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | | 著者 | Lin, C, Zhang, J, Li, J. | | 登録日 | 2022-12-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
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8HUT
 | | Crystal structure of MERS main protease in complex with S217622 | | 分子名称: | 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, ORF1a | | 著者 | Lin, C, Zhang, J, Li, J. | | 登録日 | 2022-12-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
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8HUV
 | | Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with S217622 | | 分子名称: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | | 著者 | Zeng, P, Zhang, J, Li, J. | | 登録日 | 2022-12-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
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8HUU
 | | Crystal structure of HCoV-NL63 main protease with S217622 | | 分子名称: | 3C-like proteinase, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | | 著者 | Zeng, X.Y, Zhang, J, Li, J. | | 登録日 | 2022-12-24 | | 公開日 | 2023-06-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
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5ZZ9
 | | Crystal structure of Homer2 EVH1/Drebrin PPXXF complex | | 分子名称: | Homer protein homolog 2, Peptide from Drebrin | | 著者 | Li, Z, Liu, H, Li, J, Liu, W, Zhang, M. | | 登録日 | 2018-05-31 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Homer Tetramer Promotes Actin Bundling Activity of Drebrin.
Structure, 27, 2019
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5DQT
 | | Crystal Structure of Cas-DNA-22 complex | | 分子名称: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (33-MER), ... | | 著者 | Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y. | | 登録日 | 2015-09-15 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
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6W0E
 | | Open-gate KcsA soaked in 10 mM BaCl2 | | 分子名称: | BARIUM ION, Fab Heavy Chain, Fab Light Chain, ... | | 著者 | Rohaim, A, Gong, L, Li, J. | | 登録日 | 2020-02-29 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.512 Å) | | 主引用文献 | Open and Closed Structures of a Barium-Blocked Potassium Channel.
J.Mol.Biol., 432, 2020
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6LPF
 | | The crystal structure of human cytoplasmic LRS | | 分子名称: | 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL, ... | | 著者 | Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D. | | 登録日 | 2020-01-10 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.
Nucleic Acids Res., 48, 2020
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6W0F
 | | Closed-gate KcsA soaked in 0mM KCl/5mM BaCl2 | | 分子名称: | Fab Heavy Chain, Fab Light Chain, POTASSIUM ION, ... | | 著者 | Rohaim, A, Gong, L, Li, J. | | 登録日 | 2020-02-29 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Open and Closed Structures of a Barium-Blocked Potassium Channel.
J.Mol.Biol., 432, 2020
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5DLJ
 | | Crystal Structure of Cas-DNA-N1 complex | | 分子名称: | 39-mer DNA N1-F, 39-mer DNA N1-R, CRISPR-associated endonuclease Cas1, ... | | 著者 | Wang, J, Li, J, Zhao, H, Sheng, G, Wang, M, Yin, M, Wang, Y. | | 登録日 | 2015-09-05 | | 公開日 | 2015-11-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.
Cell, 163, 2015
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6LR6
 | | The crystal structure of human cytoplasmic LRS | | 分子名称: | 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... | | 著者 | Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D. | | 登録日 | 2020-01-15 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.009 Å) | | 主引用文献 | Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.
Nucleic Acids Res., 48, 2020
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8WF7
 | | The Crystal Structure of integrase from Biortus | | 分子名称: | ACETATE ION, Integrase, SULFATE ION | | 著者 | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | | 登録日 | 2023-09-19 | | 公開日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The Crystal Structure of integrase from Biortus
To Be Published
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8X2S
 | | The Crystal Structure of BPGM from Biortus | | 分子名称: | 1,2-ETHANEDIOL, Bisphosphoglycerate mutase | | 著者 | Wang, F, Cheng, W, Yuan, Z, Qi, J, Li, J. | | 登録日 | 2023-11-10 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Crystal Structure of BPGM from Biortus
To Be Published
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6LKA
 | | Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds | | 分子名称: | 3C proteinase, ~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide | | 著者 | Li, P, Wu, S.Q, Xiao, T.Y.C, Li, Y.L, Su, Z.M, Hao, F, Hu, G.P, Hu, J, Lin, F.S, Chen, X.S, Gu, Z.X, He, H.Y, Li, J, Chen, S.H. | | 登録日 | 2019-12-18 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.033 Å) | | 主引用文献 | Design, synthesis, and evaluation of a novel macrocyclic anti-EV71 agent.
Bioorg.Med.Chem., 28, 2020
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3H8K
 | | Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution | | 分子名称: | Autocrine motility factor receptor, isoform 2, Ubiquitin-conjugating enzyme E2 G2 | | 著者 | Kalathur, R.C, Das, R, Li, J, Byrd, R.A, Ji, X. | | 登録日 | 2009-04-29 | | 公開日 | 2009-07-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78.
Mol.Cell, 34, 2009
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8WF4
 | | The Crystal Structure of RSK1 from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, Ribosomal protein S6 kinase alpha-1 | | 著者 | Wang, F, Cheng, W, Lv, Z, Qi, J, Li, J. | | 登録日 | 2023-09-19 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | The Crystal Structure of RSK1 from Biortus.
To Be Published
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