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1UQR
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BU of 1uqr by Molmil
Type II 3-dehydroquinate dehydratase (DHQase) from Actinobacillus pleuropneumoniae
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-DEHYDROQUINATE DEHYDRATASE, SULFATE ION
著者Maes, D, Gonzalez-Ramirez, L.A, Lopez-Jaramillo, J, Yu, B, De Bondt, H, Zegers, I, Afonina, E, Garcia-Ruiz, J.M, Gulnik, S.
登録日2003-10-16
公開日2003-10-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Study of the Type II 3-Dehydroquinate Dehydratase from Actinobacillus Pleuropneumoniae
Acta Crystallogr.,Sect.D, 60, 2004
2HBQ
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BU of 2hbq by Molmil
Crystal structure of wildtype human caspase-1 in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-06-14
公開日2006-06-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Common Allosteric Site and Mechanism in Caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2GMR
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BU of 2gmr by Molmil
Photosynthetic reaction center mutant from Rhodobacter sphaeroides with Asp L210 replaced with Asn
分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (II) ION, ...
著者Stachnik, J.M, Hermes, S, Gerwert, K, Hofmann, E.
登録日2006-04-07
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Proton uptake in the reaction center mutant L210DN from Rhodobacter sphaeroides via protonated water molecules.
Biochemistry, 45, 2006
1UNV
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BU of 1unv by Molmil
Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles
分子名称: GENERAL CONTROL PROTEIN GCN4
著者Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R.
登録日2003-09-15
公開日2004-10-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides
Biochemistry, 44, 2005
1UQW
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BU of 1uqw by Molmil
Crystal structure of yliB protein from escherichia coi
分子名称: GLYCEROL, PUTATIVE BINDING PROTEIN YLIB, ZINC ION
著者Jeudy, S, Abergel, C, Claverie, J.M.
登録日2003-10-22
公開日2003-10-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Crystal Structure of Ylib Protein from E.Coli
To be Published
2GZV
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BU of 2gzv by Molmil
The cystal structure of the PDZ domain of human PICK1
分子名称: PRKCA-binding protein
著者Debreczeni, J.E, Elkins, J.M, Yang, X, Berridge, G, Bray, J, Colebrook, S, Smee, C, Savitsky, P, Gileadi, O, Turnbull, A, von Delft, F, Doyle, D.A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Structural Genomics Consortium (SGC)
登録日2006-05-12
公開日2006-07-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
1UVK
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The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex
分子名称: GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
登録日2004-01-21
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
2GU8
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Discovery of 2-Pyrimidyl-5-Amidothiophenes as Novel and Potent Inhibitors for AKT: Synthesis and SAR Studies
分子名称: CAMP-dependent protein kinase, alpha-catalytic subunit, N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE, ...
著者Murray, J.M.
登録日2006-04-28
公開日2007-05-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies
Bioorg.Med.Chem.Lett., 16, 2006
1D6H
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BU of 1d6h by Molmil
CHALONE SYNTHASE (N336A MUTANT COMPLEXED WITH COA)
分子名称: CHALCONE SYNTHASE, COENZYME A, SULFATE ION
著者Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P.
登録日1999-10-13
公開日2000-02-03
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry, 39, 2000
2H48
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Crystal structure of human caspase-1 (Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase 1, isoform gamma, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-05-23
公開日2006-06-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A common allosteric site and mechanism in caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2H54
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Crystal structure of human caspase-1 (Thr388->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-05-25
公開日2008-03-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An allosteric circuit in caspase-1.
J.Mol.Biol., 381, 2008
2H72
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Crystal Structure of Thioredoxin mutant E85D in Hexagonal (p61) Space Group
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin
著者Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
登録日2006-06-01
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Thioredoxin mutant E85D in Hexagonal (p61) Space Group
To be Published
2GL0
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Structure of PAE2307 in complex with adenosine
分子名称: ADENOSINE, PHOSPHATE ION, conserved hypothetical protein
著者Lott, J.S, Paget, B, Johnston, J.M, Baker, E.N.
登録日2006-04-04
公開日2006-06-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Structure of an Ancient Conserved Domain Establishes a Structural Basis for Stable Histidine Phosphorylation and Identifies a New Family of Adenosine-specific Kinases.
J.Biol.Chem., 281, 2006
1TGY
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BU of 1tgy by Molmil
Structure of E. coli Uridine Phosphorylase complexed with uracil and ribose 1-phosphate
分子名称: 1-O-phosphono-alpha-D-ribofuranose, POTASSIUM ION, URACIL, ...
著者Bu, W, Settembre, E.C, Sanders, J.M, Begley, T.P, Ealick, S.E.
登録日2004-05-31
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of E. coli Uridine Phosphorylase
To be Published, 2004
1SRR
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BU of 1srr by Molmil
CRYSTAL STRUCTURE OF A PHOSPHATASE RESISTANT MUTANT OF SPORULATION RESPONSE REGULATOR SPO0F FROM BACILLUS SUBTILIS
分子名称: CALCIUM ION, SPORULATION RESPONSE REGULATORY PROTEIN
著者Madhusudan, Whiteley, J.M, Hoch, J.A, Zapf, J, Xuong, N.H, Varughese, K.I.
登録日1996-04-10
公開日1997-04-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a phosphatase-resistant mutant of sporulation response regulator Spo0F from Bacillus subtilis.
Structure, 4, 1996
2H6Z
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Crystal Structure of Thioredoxin Mutant E44D in Hexagonal (p61) Space Group
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin
著者Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
登録日2006-06-01
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization.
Biophys.J., 89, 2005
2H71
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BU of 2h71 by Molmil
Crystal Structure of Thioredoxin Mutant D47E in Hexagonal (p61) Space Group
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin
著者Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
登録日2006-06-01
公開日2007-05-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Thioredoxin Mutant D47E in Hexagonal (p61) Space Group
To be Published
1AIK
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BU of 1aik by Molmil
HIV GP41 CORE STRUCTURE
分子名称: HIV-1 GP41 GLYCOPROTEIN
著者Chan, D.C, Fass, D, Berger, J.M, Kim, P.S.
登録日1997-04-20
公開日1997-06-16
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Core structure of gp41 from the HIV envelope glycoprotein.
Cell(Cambridge,Mass.), 89, 1997
2H4Y
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BU of 2h4y by Molmil
Crystal structure of human caspase-1 (Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
著者Scheer, J.M, Wells, J.A, Romanowski, M.J.
登録日2006-05-25
公開日2008-03-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An allosteric circuit in caspase-1.
J.Mol.Biol., 381, 2008
1A6S
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BU of 1a6s by Molmil
M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES
分子名称: GAG POLYPROTEIN
著者Mcdonnell, J.M, Fushman, D, Cahill, S.M, Zhou, W, Wolven, A, Wilson, C.B, Nelle, T.D, Resh, M.D, Wills, J, Cowburn, D.
登録日1998-03-02
公開日1998-10-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of the bioactive retroviral M domain from Rous sarcoma virus
J.Mol.Biol., 279, 1998
2KUC
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BU of 2kuc by Molmil
Solution Structure of a putative disulphide-isomerase from Bacteroides thetaiotaomicron
分子名称: Putative disulphide-isomerase
著者Harris, R, Foti, R, Seidel, R.D, Bonanno, J.B, Freeman, J, Bain, K.T, Sauder, J.M, Burley, S.K, Girvin, M.E, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-02-17
公開日2010-03-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Structure of a putative disulphide-isomerase from Bacteroides thetaiotaomicron
To be Published
1UNW
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BU of 1unw by Molmil
Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles
分子名称: GENERAL CONTROL PROTEIN GCN4
著者Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R.
登録日2003-09-15
公開日2004-10-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides
Biochemistry, 44, 2005
2KPN
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Solution NMR structure of a Bacterial Ig-like (Big_3) domain from Bacillus cereus. Northeast Structural Genomics Consortium target BcR147A
分子名称: Bacillolysin, CALCIUM ION
著者Aramini, J.M, Wang, D, Ciccosanti, C.T, Janjua, H, Rost, B, Acton, T.B, Xiao, R, Swapna, G.V.T, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2009-10-16
公開日2010-01-12
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR structure of a Bacterial Ig-like (Big_3) domain from Bacillus cereus. Northeast Structural Genomics Consortium target BcR147A
To be Published
1UPC
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Carboxyethylarginine synthase from Streptomyces clavuligerus
分子名称: CARBOXYETHYLARGININE SYNTHASE, MAGNESIUM ION, SULFATE ION, ...
著者Caines, M.E.C, Elkins, J.M, Hewitson, K.S, Schofield, C.J.
登録日2003-09-29
公開日2003-11-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure and Mechanistic Implications of N2-(2-Carboxyethyl)Arginine Synthase, the First Enzyme in the Clavulanic Acid Biosynthesis Pathway
J.Biol.Chem., 279, 2004
1UPA
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Carboxyethylarginine synthase from Streptomyces clavuligerus (SeMet structure)
分子名称: CARBOXYETHYLARGININE SYNTHASE, MAGNESIUM ION, SULFATE ION, ...
著者Caines, M.E.C, Elkins, J.M, Hewitson, K.S, Schofield, C.J.
登録日2003-09-29
公開日2003-11-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structure and Mechanistic Implications of N2-(2-Carboxyethyl)Arginine Synthase, the First Enzyme in the Clavulanic Acid Biosynthesis Pathway
J.Biol.Chem., 279, 2004

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